ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] AZT, after intracellular phosphorylation to AZT triphosphate, competitively inhibits reverse transcriptase with regard to thymidine triphosphate11, whereas mammalian DNA polymerases do not readily accept AZT triphosphate as substrate. AZT effectively inhibits infectivity and cytopathic effects of ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/323467a0
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