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  • Geophysics  (1)
  • coronary thrombolysis  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 4 (1987), S. 375-378 
    ISSN: 1573-904X
    Keywords: thrombolytic ; tissue plasminogen activator ; plasminogen activators ; coronary thrombolysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Thrombolytic therapy has received renewed attention with the demonstration that early treatment of acute myocardial infarction with plasminogen activators can reduce mortality. Tissue plasminogen activator (t-PA) is a protein with attributes that may allow for greater efficacy and safety. Recombinant DNA technology has enabled the production of sufficient t-PA, called rt-PA (Activase), for substantial clinical evaluation. The results suggest that Activase is a significant advance in thrombolytic therapy.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2019-07-13
    Description: Rocks enriched in Ge have been discovered in Gale Crater, Mars, by the Alpha-particle X-ray spectrometer (APXS) on the Mars Science Lab (MSL) rover, Curiosity. The Ge concentrations in Gale Crater (commonly 〉50 ppm) are remarkably high in comparison to Earth, where Ge ranges from 0.5-4.0 ppm in igneous rocks and 0.2-3.3 ppm in siliciclastic sediment. Primary meteoritic input is not likely the source of high Ge because Ge/Ni in chondrites (approx.0.003) and irons (〈0.04) is lower than in Gale rocks (0.08-0.2). Earth studies show Ge is a useful geochemical tracer because it is coherent with Si during magmatic processes and Ge/Si varies less than 20% in basalts. Ge and Si fractionate during soil/regolith weathering, with Ge preferentially sequestered in clays. Ge is also concentrated in Cu- and Zn-rich hydrothermal sulfide deposits and Fe- and Mnrich oxide deposits. Other fluid-mobile elements (K, Zn, Cl, Br, S) are also enriched at Gale and further constrain aqueous alteration processes. Here, we interpret the sediment alteration history and present a possible model for Ge enrichments at Gale involving fluid alteration of the protolith.
    Keywords: Geophysics
    Type: JSC-CN-32857 , Lunar and Planetary Science Conference; Mar 16, 2015 - Mar 20, 2015; The Woodlands, TX; United States
    Format: application/pdf
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