Publication Date:
2011-01-15
Description:
Circadian regulation of plant-animal endosymbioses is complicated by a diversity of internal and external cues. Here, we show that stress-related genes in corals are coupled to the circadian clock, anticipating major changes in the intracellular milieu. In this regard, numerous chaperones are "hard-wired" to the clock, effectively preparing the coral for the consequences of oxidative protein damage imposed by symbiont photosynthesis (when O(2) 〉 250% saturation), including synexpression of antioxidant genes being light-gated. Conversely, central metabolism appears to be regulated by the hypoxia-inducible factor system in coral. These results reveal the complexity of endosymbiosis as well as the plasticity regulation downstream of the circadian clock.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levy, O -- Kaniewska, P -- Alon, S -- Eisenberg, E -- Karako-Lampert, S -- Bay, L K -- Reef, R -- Rodriguez-Lanetty, M -- Miller, D J -- Hoegh-Guldberg, O -- New York, N.Y. -- Science. 2011 Jan 14;331(6014):175. doi: 10.1126/science.1196419.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21233378" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Anthozoa/*genetics/physiology
;
Biosynthetic Pathways/genetics
;
*Circadian Clocks
;
Circadian Rhythm
;
Dinoflagellida/*physiology
;
*Gene Expression Regulation
;
Glycolysis/genetics
;
Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism
;
Molecular Chaperones/genetics
;
Oligonucleotide Array Sequence Analysis
;
Oxidation-Reduction
;
Stress, Physiological
;
*Symbiosis
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
