ISSN:
0947-3440
Keywords:
Synthesis, Stereoselective
;
Oligo(tetrahydrofurans), natural, non-natural
;
Ion channels, artificial
;
Annonaceae acetogenins
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The „dimeric“ and „trimeric“ oligo(tetrahydrofurans) (oligo-THFs) 24, 28, 32, and 38 were synthesized stereoselectively according to a linear and a convergent synthetic strategy. The oligo-THFs thus obtained are important intermediates for the synthesis of artificial ion channels. Furthermore, they can be used in the total synthesis of Annonaceae acetogenins, a class of natural occurring oligo-THFs with promising pharmacological properties.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1995199508192
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