Publication Date:
2010-09-11
Description:
Plants and animals produce modular developmental units in a periodic fashion. In plants, lateral roots form as repeating units along the root primary axis; however, the developmental mechanism regulating this process is unknown. We found that cyclic expression pulses of a reporter gene mark the position of future lateral roots by establishing prebranch sites and that prebranch site production and root bending are periodic. Microarray and promoter-luciferase studies revealed two sets of genes oscillating in opposite phases at the root tip. Genetic studies show that some oscillating transcriptional regulators are required for periodicity in one or both developmental processes. This molecular mechanism has characteristics that resemble molecular clock-driven activities in animal species.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976612/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976612/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Moreno-Risueno, Miguel A -- Van Norman, Jaimie M -- Moreno, Antonio -- Zhang, Jingyuan -- Ahnert, Sebastian E -- Benfey, Philip N -- R01 GM043778/GM/NIGMS NIH HHS/ -- R01 GM043778-19/GM/NIGMS NIH HHS/ -- R01 GM043778-20/GM/NIGMS NIH HHS/ -- R01 GM043778-21/GM/NIGMS NIH HHS/ -- R01-GM043778/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2010 Sep 10;329(5997):1306-11. doi: 10.1126/science.1191937.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology and Institute for Genome Sciences and Policy Center for Systems Biology, Duke University, Durham, NC 27708, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20829477" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/cytology/*genetics/*growth & development/metabolism
;
Arabidopsis Proteins/genetics/metabolism
;
Gene Expression Profiling
;
*Gene Expression Regulation, Plant
;
Gene Regulatory Networks
;
Genes, Plant
;
Genes, Reporter
;
Gravitation
;
Indoleacetic Acids/metabolism/pharmacology
;
Meristem/*genetics/*growth & development/metabolism
;
Oligonucleotide Array Sequence Analysis
;
Phthalimides/pharmacology
;
Plant Roots/cytology/genetics/*growth & development
;
Promoter Regions, Genetic
;
Signal Transduction
;
Temperature
;
Time Factors
;
Transcription Factors/genetics/metabolism
;
Transcription, Genetic
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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