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  • 1
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    Ein frühpleistozänes Kalkartefakt von Würzburg-Schalksberg (2011)
    Geozon Science Media
    Details
    Publication Date: 2021-03-29
    Description: In den Jahren 1966 und 1976 wurden bei Ausschachtungsarbeiten in Würzburg-Schalksberg zahlreiche mauerzeitliche Faunenreste aus alten Ablagerungen des Mains geborgen. Zusammen mit den nichtumgelagerten, z.T. bearbeiteten Knochen wurden Werkzeuge aus Kalk entdeckt, die in altpleistozäner Technik hergestellt wurden.
    Description: research
    Keywords: 551.7 ; VAR 000 ; Glazialgeologie ; excavations ; limestone-implements ; homo heidelhergensis ; animal bones
    Language: German
    Type: article , publishedVersion
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    CITATION GEO-LEO
  • 2
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    Über neue Artefaktfunde aus der Heidelberger Stufe (2011)
    Geozon Science Media
    Details
    Publication Date: 2021-03-29
    Description: Nach der Entdeckung altpleistozäner Artefakte der Heidelberger Stufe in Norddeutschland und bei Mauer ließ sich der erkennbare Lebensraum des Homo heidelbergensis jetzt wesentlich ausweiten. Neue Funde aus den präglazialen Terrassen von Süssenborn bei Weimar erwiesen eine Besiedlung auch Mitteldeutschlands, und gleichartige Funde aus den ältesten Donauterrassen bei Wien werden als Hinweis auf eine weitgehend nach Osten in den Kontinent hineinreichende Besiedlung durch den Heidelberger Menschen aufgefaßt. Artefaktfunde aus den Rheinschottern bei Brüggen führen an die plio-pleistozäne Grenze. Im Nachtrag werden Heidelberger Artefakte aus den oberpliozänen Schottern von Sülzfeld in Thüringen angeführt, die den Artefakten von Mauer typologisch sehr nahestehen.
    Description: research
    Keywords: 551.7 ; VAR 000 ; Glazialgeologie ; norddeutschland ; wien ; heidelberger stufe ; altpleistozän ; niederrhein ; oberpliozän ; homo heidelbergensis ; artefakt ; donauterrasse ; mauer ; ilm-terrassenschotter ; süßenborn ; brüggen ; ältestdiluviale schotter ; altersstellung ; sülzfeld/meiningen ; thüringen ; weimar ; rheinschotter ; plio-pleistozän
    Language: German
    Type: article , publishedVersion
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  • 3
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    Zur relativen und absoluten Geochronologie der Reliefentwicklung an der Küste des mittleren Südwestafrika (2011)
    Geozon Science Media
    Details
    Publication Date: 2021-03-29
    Description: Ergebnisse quartärgeomorphologischer Arbeiten an der Namibküste werden präsentiert. Dort lassen sich zwei Meereshochstände, ein Meerestiefstand nachweisen. Der jüngere Meereshochstand ist nach l4C-Datierungen ins Innerwürm zu stellen (ca. 26 000 B.P.). Er ist eindeutig eustatisch. Jungquartäre Vertikaltektonik im Küstenbereich ist nicht auszuschließen. Die zeitlichen Änderungen des Meeresspiegels werden mit Phasen der terrestrischen Morphogenese verknüpft. Meereshochstände korrelieren mit „trockenen", Meerestiefstände mit „feuchten" „Klima"-Bedingungen.
    Description: research
    Keywords: 551.7 ; VAR 000 ; Glazialgeologie ; geochronologie ; reliefentwicklung ; küste ; südwestafrika ; quartärgeomorphologie ; meeresspiegelschwankung ; namib
    Language: German
    Type: article , publishedVersion
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  • 4
    Electronic Resource
    Electronic Resource
    Chemical heterogeneity of soldier defensive secretions in the desert subterranean termite, Amitermes wheeleri
    Amsterdam : Elsevier
    Biochemical Systematics and Ecology 14 (1986), S. 661-664 
    Details
    ISSN: 0305-1978
    Keywords: Amitermes wheeleri ; Isoptera ; Termitidae ; chemosystematics ; defensive secretions ; intraspecific variation ; sesquiterpenoids ; termite soldiers
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0305-1978(86)90049-9
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Soldier defensive secretions of two rare nearctic desert termite species
    Amsterdam : Elsevier
    Biochemical Systematics and Ecology 16 (1988), S. 213-216 
    Details
    ISSN: 0305-1978
    Keywords: 4,11-epoxy-cis-eudesmane ; Amitermes coachellae ; Amitermes emersoni ; Amitermitinae ; Isoptera ; Termitidae ; biogeography ; phylogeny ; soldier defensive secretions ; terpenes
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0305-1978(88)90099-3
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  • 6
    Electronic Resource
    Electronic Resource
    Drywood termite feeding deterrents in sugar pine and antitermitic activity of related compounds (1983)
    Springer
    Journal of chemical ecology 9 (1983), S. 39-55 
    Details
    ISSN: 1573-1561
    Keywords: Feeding deterrents ; drywood termites ; Incisitermes minor ; Isoptera ; Kalotermitidae ; sugar pine ; Pinus lambertiana ; fatty acids α-halogenated acids ; esters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The feeding deterrent activity of sapwood extracts of sugar pine,Pinus lambertiana Dougl., and related compounds was determined against immatures of the western drywood termite,Incisitermes minor (Hagen). A bioassay was designed to quantify reductions in termite feeding caused by deterrent chemicals. Crude extracts and isolated fractions of sugar pine were deterrent and not preferred byI. minor at 0.5 mg/cm2. Fatty acids occurring in sugar pine extracts had a broad range of deterrent activity. Long-chain saturated fatty acids were deterrent at 0.25 and 0.05 mg/cm2. Unsaturated or intermediate length (C8-C14) acids, many not found in sugar pine wood, were less active than long-chain saturated acids. Related alpha-halogenated compounds were highly deterrent at 0.05 mg/cm2 regardless of chain length or presence of a carboxylic acid moiety. Deposits of 2-iodooctadecanoic acid reduced termite feeding at 5 μg/cm2, while 2-bromooctadecanoic acid had deterrent activity comparable to commercial wood preservatives. None of the halogenated compounds tested were termiticidal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00987769
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  • 7
    Electronic Resource
    Electronic Resource
    Identification of the defensive secretion from soldiers of the North American termite,Amitermes wheeleri (Desneux) (Isoptera: Termitidae) (1983)
    Springer
    Journal of chemical ecology 9 (1983), S. 1293-1305 
    Details
    ISSN: 1573-1561
    Keywords: Amitermes wheeleri ; Isoptera ; Termitidae ; termite soldiers ; defensive secretion ; ant repellents ; α-bisabolene ; β-bisabolene ; α2-bisabolene ; Iridomyrmex humilis ; Pogonomyrmex rugosus ; sesquiterpenes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Head capsule extracts ofAmitermes wheeleri soldiers yielded an isomeric mixture (67 μg/ soldier) of three sesquiterpene hydrocarbons identified by EIMS, [13C]-, and [1H]NMR as (+)-(S,Z)-α-bisabolene (53%), (+)-(R)-β-bisabolene (16%), and (−)-(Z)-α2-bisabolene (31%). When alarmed, the termite soldiers secreted the fluid onto the head surface surrounding the efferent pore of the frontal gland reservoir. A defensive function for the soldier secretion was indicated by the avoidance behavior displayed toward alarmed soldiers by the antagonistic ants,Pogonomyrmex rugosus andIridomyrmex humilis. Laboratory studies demonstrated that the sesquiterpene mixture is repellent to foragingI. humilis workers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00994798
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  • 8
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    A genomic regulatory network for development (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-03-02
    Description: Development of the body plan is controlled by large networks of regulatory genes. A gene regulatory network that controls the specification of endoderm and mesoderm in the sea urchin embryo is summarized here. The network was derived from large-scale perturbation analyses, in combination with computational methodologies, genomic data, cis-regulatory analysis, and molecular embryology. The network contains over 40 genes at present, and each node can be directly verified at the DNA sequence level by cis-regulatory analysis. Its architecture reveals specific and general aspects of development, such as how given cells generate their ordained fates in the embryo and why the process moves inexorably forward in developmental time.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davidson, Eric H -- Rast, Jonathan P -- Oliveri, Paola -- Ransick, Andrew -- Calestani, Cristina -- Yuh, Chiou-Hwa -- Minokawa, Takuya -- Amore, Gabriele -- Hinman, Veronica -- Arenas-Mena, Cesar -- Otim, Ochan -- Brown, C Titus -- Livi, Carolina B -- Lee, Pei Yun -- Revilla, Roger -- Rust, Alistair G -- Pan, Zheng jun -- Schilstra, Maria J -- Clarke, Peter J C -- Arnone, Maria I -- Rowen, Lee -- Cameron, R Andrew -- McClay, David R -- Hood, Leroy -- Bolouri, Hamid -- GM-61005/GM/NIGMS NIH HHS/ -- HD-37105/HD/NICHD NIH HHS/ -- RR-06591/RR/NCRR NIH HHS/ -- RR-15044/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 2002 Mar 1;295(5560):1669-78.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA. davidson@caltech.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11872831" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Lineage ; Computational Biology ; Embryonic Development ; Endoderm/cytology/*physiology ; Gene Expression Profiling ; *Gene Expression Regulation, Developmental ; Genes, Regulator ; *Genome ; Mesoderm/cytology/*physiology ; Models, Biological ; Models, Genetic ; Morphogenesis ; Regulatory Sequences, Nucleic Acid ; Sea Urchins/*embryology/*genetics ; Stem Cells/physiology ; Systems Theory
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    A great-appendage arthropod with a radial mouth from the Lower Devonian Hunsruck Slate, Germany (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-02-07
    Description: Great-appendage arthropods, characterized by a highly modified anterior limb, were previously unknown after the Middle Cambrian. One fossil from the Lower Devonian Hunsruck Slate, Germany, extends the stratigraphic range of these arthropods by approximately 100 million years. Schinderhannes bartelsi shows an unusual combination of anomalocaridid and euarthropod characters, including a highly specialized swimming appendage. A cladistic analysis indicates that the new taxon is basal to crown-group euarthropods and that the great-appendage arthropods are paraphyletic. This new fossil shows that features of the anomalocaridids, including the multisegmented raptorial appendage and circular plated mouth, persisted long after the initial radiation of the euarthropods.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kuhl, Gabriele -- Briggs, Derek E G -- Rust, Jes -- New York, N.Y. -- Science. 2009 Feb 6;323(5915):771-3. doi: 10.1126/science.1166586.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Palaeontology, Steinmann Institute, University of Bonn, Nussallee 8, 53115 Bonn, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19197061" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arthropods/*anatomy & histology/*classification ; Extremities/anatomy & histology ; *Fossils ; Germany ; Mouth/anatomy & histology ; Phylogeny
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses (2012)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2012-09-18
    Description: Antiviral responses must be tightly regulated to defend rapidly against infection while minimizing inflammatory damage. Type 1 interferons (IFN-I) are crucial mediators of antiviral responses and their transcription is regulated by a variety of transcription factors; principal among these is the family of interferon regulatory factors (IRFs). The IRF gene regulatory networks are complex and contain multiple feedback loops. The tools of systems biology are well suited to elucidate the complex interactions that give rise to precise coordination of the interferon response. Here we have used an unbiased systems approach to predict that a member of the forkhead family of transcription factors, FOXO3, is a negative regulator of a subset of antiviral genes. This prediction was validated using macrophages isolated from Foxo3-null mice. Genome-wide location analysis combined with gene deletion studies identified the Irf7 gene as a critical target of FOXO3. FOXO3 was identified as a negative regulator of Irf7 transcription and we have further demonstrated that FOXO3, IRF7 and IFN-I form a coherent feed-forward regulatory circuit. Our data suggest that the FOXO3-IRF7 regulatory circuit represents a novel mechanism for establishing the requisite set points in the interferon pathway that balances the beneficial effects and deleterious sequelae of the antiviral response.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556990/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556990/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Litvak, Vladimir -- Ratushny, Alexander V -- Lampano, Aaron E -- Schmitz, Frank -- Huang, Albert C -- Raman, Ayush -- Rust, Alistair G -- Bergthaler, Andreas -- Aitchison, John D -- Aderem, Alan -- HHSN272200700038C/AI/NIAID NIH HHS/ -- HHSN272200700038C/PHS HHS/ -- HHSN272200800058C/AI/NIAID NIH HHS/ -- HSN272200800058C/PHS HHS/ -- R01 AI025032/AI/NIAID NIH HHS/ -- R01 AI032972/AI/NIAID NIH HHS/ -- R01AI025032/AI/NIAID NIH HHS/ -- R01AI032972/AI/NIAID NIH HHS/ -- U19 AI100627/AI/NIAID NIH HHS/ -- U54 GM103511/GM/NIGMS NIH HHS/ -- U54 RR022220/RR/NCRR NIH HHS/ -- U54GM103511/GM/NIGMS NIH HHS/ -- England -- Nature. 2012 Oct 18;490(7420):421-5. doi: 10.1038/nature11428. Epub 2012 Sep 16.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Seattle Biomedical Research Institute, Seattle, Washington 98109, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22982991" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Female ; Forkhead Transcription Factors/deficiency/genetics/*metabolism ; Gene Deletion ; Gene Expression Regulation/*immunology ; Inflammation/genetics/*immunology/*pathology ; Interferon Regulatory Factor-7/deficiency/genetics/*metabolism ; Interferon Type I/immunology ; Lung/immunology/pathology/virology ; Macrophages/immunology ; Mice ; Mice, Inbred C57BL ; Reproducibility of Results ; Vesiculovirus/*immunology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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