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  • Aerospace Medicine  (2)
  • Analytical Chemistry and Spectroscopy  (2)
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 5 (1991), S. 299-302 
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The molecular weights of the recombinant proteins interleukin 2 and interferon gamma were determined by electrospray ionization (ESI) mass spectroscopy on the whole molecules. For interleukin 2 an average experimental mass of 15 549.4 u, was observed in excellent agreement with the theoretical average mass of 15 547.2 u. The mass observed for interferon gamma (16 908.4 u) agreed with the theoretical molecular weight of the monomeric species (16 907.3 u). By ESI mass spectrometry it was possible to determine the presence of proteins lacking one or two amino acids.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    X-Ray Spectrometry 5 (1976), S. 175-177 
    ISSN: 0049-8246
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The cheapness of modern minicomputers coupled with the need for rapid and accurate output of X-ray fluorescence analytical data makes the use of computers almost obligatory. The minicomputer has the advantages of immediate availability of results over other methods. In laboratories with an annual output of less than 10 000 determinations the on-line card -punch or magnetic-tape reader coupled through a terminal to a central computer is equally effective though slower.
    Additional Material: 3 Ill.
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  • 3
    Publication Date: 2019-08-16
    Description: Future missions in space (such as a mission to Mars) will involve long-term travel beyond the magnetic field of the Earth. As a result, astronauts will be exposed to radiation qualities and doses that differ from those experienced in low earth orbit, including exposure to heavy particles, such as Fe-56, which are a component of cosmic rays. Although the hazards of exposure to heavy particles are often minimized, they can affect neural functioning, and as a consequence, behavior. Unless the effects of exposure to cosmic rays can somehow be reduced, their effects on the brain throughout long duration flights could be disastrous. In the extreme case, it is possible that the effects of cosmic rays on space travelers could result in symptomatology resembling that of Alzheimer's or Parkinson's diseases or of advancing age, including significant cognitive and/or motor impairments. Because successful operations in space depend in part on the performance capabilities of astronauts, such impairments could jeopardize their ability to satisfy mission requirements, as well as have long-term consequences on the health of astronauts. As such, understanding the nature and extent of this risk may be vital to the effective performance and possibly the survival of astronauts during future missions in space.
    Keywords: Aerospace Medicine
    Type: Proceedings of the First Biennial Space Biomedical Investigators' Workshop; 517-519
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  • 4
    Publication Date: 2019-07-13
    Description: Major risks associated with radiation exposures on deep space missions include carcinogenesis due to heavy-particle exposure of cancer-prone tissues and performance decrements due to neurological damage produced by heavy particles. Because exposure to heavy particles can cause oxidative stress, it is possible that antioxidants can be used to mitigate these risks (and possibly some health risks of microgravity). To assess the capacity of antioxidant diets to mitigate the effects of exposure to heavy particles, rats were maintained on antioxidant diets containing 2% blueberry or strawberry extract or a control diet for 8 weeks prior to exposure to 1.5 or 2.0 Gy of accelerated iron particles at Brookhaven National Laboratory. Following irradiation rats were tested on a series of behavioral tasks: amphetamine-induced taste aversion learning, operant responding and spatial learning and memory. The results indicated that the performance of the irradiated rats maintained on the antioxidant diets was, in general, significantly better than that of the control animals, although the effectiveness of the diets ameliorating the radiation-induced deterioration in performance varied as a function of both the specific diet and the specific endpoint. In addition, animals fed antioxidant diets prior to exposure showed reduced heavy particle-induced tumorigenesis one year after exposure compared to the animals fed the control diet. These results suggest that antioxidant diets have the potential to serve as part of a system designed to provide protection to astronauts against the effects of heavy particles on exploratory missions outside the magnetic field of the earth.
    Keywords: Aerospace Medicine
    Type: Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology (ISSN 1089-988X); 18; 2; 71-7
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