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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 6 (1985), S. 415-425 
    ISSN: 0197-8462
    Keywords: air ions ; DC electric fields ; brain catecholamines ; dopamine ; norepinephrine ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Exposure to air ions has been reported to influence serotonin (5HT), although critical reviews of these studies and previous measurements in our laboratory of the concentration, release, and utilization of brain 5HT indicate that neither the data nor the interpretations of the data are particularly convincing. Measurements of other possibly relevant neuro-transmitter systems - norepinephrine (NE) and dopamine (DA) - were made in brain regions selected because of their importance in the modulation of brain functions relating to motivation, arousal, endocrine function, and motor activity, all responses that have been reported to be influenced by air ion exposure. Results indicate that exposure of male Holtzman rats to high concentrations (5.0 × 105/cm3) of positive or negative air ions or to DC electric fields (3.0 kV/m) for periods up to 66 h failed to affect the concentration of NE or DA significantly in any of the brain regions.
    Additional Material: 6 Tab.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 8 (1987), S. 173-181 
    ISSN: 0197-8462
    Keywords: DC electric fields ; 5-hydroxyindoleacetic acid ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Exposure to electrically charged gas molecules (air ions) has been reported to influence physiological and behavioral functions in animals and humans although there is controversy as to whether these findings are valid. A popular hypothesis concerning the reported effects of air ions is that alterations in serotonin (5HT) metabolism, particularly in the brain, are involved. We measured the concentration and turnover of 5HT in rats exposed to 5.0 × 105 ions/cm3 for up to 66 hours. Contrary to previous reports of other investigators, we were unable to demonstrate any effect of exposure to air ions or associated DC electric fields on the concentration or turnover of 5HT in rats under carefully controlled and characterized exposure conditions.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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