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  • Adrenal zona glomerulosa  (2)
  • Blood velocity  (2)
  • 18-oxo-cortisol (18-oxo-F)  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Steroid Biochemistry 28 (1987), S. 441-443 
    ISSN: 0022-4731
    Keywords: 11β,17α,21-Trihydroxy-pregn-4-ene-3,18,20-trione ; 18-oxo-cortisol (18-oxo-F)
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 17 (1979), S. 316-322 
    ISSN: 1741-0444
    Keywords: Blood velocity ; Directional Doppler ; Spectrum analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A real-time dual channel time compression spectrum analyser is described, which has been optimised for use in analysis of Doppler-shifted ultrasound. Detailed block diagrams of the circuitry utilised are given.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0878
    Keywords: Pregnancy ; Adrenal zona glomerulosa ; Juxtaglomerular apparatus ; Ultrastructure ; Sheep
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructural changes in the adrenal zona glomerulosa and renal juxtaglomerular apparatus have been examined during normal pregnancy in sheep. As pregnancy progressed, increasing numbers of cells in the adrenal zona glomerulosa displayed mitochondria with straight tubular “rod-like” structures replacing their normal lamelliform cristae; groups of cells showing these mitochondrial changes were predominantly located in the middle and superficial regions of the zona glomerulosa, but at all stages remained interspersed with cells with apparently normal mitochondria. In the same animals, the renal juxtaglomerular index was raised, reflecting an increase in renin storage, and juxtaglomerular myoepithelioid cells showed increased numbers of cytoplasmic granules, but no apparent increase in granular endoplasmic reticulum and Golgi profiles; there were no distinguishing morphological changes in juxtaglomerular peripolar cells. These findings provide morphologic evidence of stimulation of the adrenal zona glomerulosa in association with increased juxtaglomerular renin storage during pregnancy. The mitochondrial changes observed in an increasing proportion of cells in the zona glomerulosa closely resemble those seen in sodium-depleted animals, and may reflect the altered steroidogenic capacity of the adrenal gland in pregnant sheep. The finding of groups of cells displaying altered mitochondria lying next to cells with normal mitochondria suggests the presence of cells with different sensitivities to stimuli for aldosterone production or may indicate the presence of different cell types in the zona glomerulosa responding to different stimuli.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0878
    Keywords: Adrenal zona glomerulosa ; Ultrastructure ; Sodium depletion ; Sodium loading ; Sheep
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of alterations in sodium status upon the morphology of the adrenal zona glomerulosa in sheep have been examined qualitatively and quantitatively, using lightand electron microscopy, and correlated with functionally related biochemical data. With severe sodium depletion induced by parotid-cannula drainage, there was mitotic activity throughout the zona glomerulosa, and glandular cells showed striking ultrastructural changes. These changes particularly affected mitochondria, which were enlarged, rounded and showed replacement of their normal lamelliform cristae by thin elongated cristal elements and bundles of tubular “rod-like” structures. Quantitative morphometric studies showed an increase in the volumes of zona glomerulosa cells, nuclei, mitochondria, smooth and granular endoplasmic reticulum, and Golgi profiles. In contrast, with dietary sodium loading, zona glomerulosa cells appeared shrunken and showed cytoplasmic lipid accumulation; mitochondria and other organelles were not significantly altered. The correlation of the ultrastructural cytological alterations in zona glomerulosa cells in sodium-depleted sheep with raised blood aldosterone levels suggests that such morphologic changes reflect a heightened capacity of these cells for aldosterone biosynthesis and secretion. These changes may also account for the increased sensitivity of the zona glomerulosa to aldosterone-producing stimuli during sodium deficiency.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 16 (1978), S. 549-553 
    ISSN: 1741-0444
    Keywords: Blood velocity ; Directional Doppler ; Spectrum analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Description / Table of Contents: Sommaire Décrit deux dispositifs de traitement préliminaire qui peuvent tous deux être utilisés avant l'analyse spectrale pour afficher sans ambiguïté les formes d'onde directionnelle de vitesse du sang par un appareil d'analyse spectral. Les détails de circuits intéressants sont présentés.
    Abstract: Zusammenfassung Es werden zwei Vorverarbeitungsanlagen beschrieben, von denen jede vor der Spektralanalyse verwendet werden kann, damit der Spektrumanalysator keine unklaren Blutgeschwindigkeitswellenformen anzeigt. Es werden wichtige Einzelheiten des Schaltkreises dargestellt.
    Notes: Abstract Two processors are described, either of which may be used before spectral analysis to allow unambiguous display of directional blood-velocity waveforms by the spectrum analyser. The relevant circuit details are presented.
    Type of Medium: Electronic Resource
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