Publikationsdatum:
1979-10-26
Beschreibung:
A single intrathecal injection of capsaicin depletes substance P from primary sensory neurons and causes a prolonged increase in the thermal and chemical pain thresholds of the rat but no apparent change in responses to noxious mechanical stimuli.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yaksh, T L -- Farb, D H -- Leeman, S E -- Jessell, T M -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):481-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/228392" target="_blank"〉PubMed〈/a〉
Schlagwort(e):
Animals
;
Capsaicin/*pharmacology
;
Fatty Acids, Unsaturated/*pharmacology
;
Hot Temperature
;
Injections, Spinal
;
Movement/drug effects
;
Nociceptors/drug effects
;
Pain/*physiopathology
;
Rats
;
Spinal Cord/*metabolism
;
Substance P/administration & dosage/*metabolism
;
Synaptic Transmission/drug effects
Print ISSN:
0036-8075
Digitale ISSN:
1095-9203
Thema:
Biologie
,
Chemie und Pharmazie
,
Informatik
,
Medizin
,
Allgemeine Naturwissenschaft
,
Physik
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