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  • Institute of Physics  (128)
  • Springer  (68)
  • 1
    Electronic Resource
    Electronic Resource
    Book reviews (1996)
    Springer
    Mineralium deposita 31 (1996), S. 250-252 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00204035
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  • 2
    Electronic Resource
    Electronic Resource
    How lesioning the nucleus praeeminentialis affects electrolocation behavior in the weakly electric fish, Apteronotus leptorhynchus (1996)
    Springer
    Journal of comparative physiology 179 (1996), S. 353-361 
    Details
    ISSN: 1432-1351
    Keywords: Behavior ; Electric fish ; Electrolocation ; Feedback pathways ; Nucleus praeeminentialis dorsalis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The ability to orient to and track moving electrolocation targets was assessed in normal Apteronotus leptorhynchus and in those with unilateral lesions of the nucleus praeeminentialis dorsalis. 1. Each fish was trained to hover between two vertical metal rods and track their movement. Two aspects of this behavior were measured: a) the hovering position of the fish relative to stationary rods; b) the latency between the onset of rod motion and the fish's tracking response. Control fish hovered midway between stationary rods, while lesioned fish hovered closer to the rod ipsilateral to the lesion. Response latency varied negatively with rod diameter in both sets of fish, and lesioned fish exhibited shorter latencies than control fish. While the response latencies of control fish were shortest when their starting position was midway between the rods, lesioned animals' latencies were shortest when they hovered closer to the rod ipsilateral to their lesion. 2. Control fish responded to the approach of a single metal ball to either side of the body with nearly equal latencies and fish-to-object distances. After lesioning, response latency increased and fish-to-object distance decreased for approaches to the side ipsilateral to the lesion; opposite changes occurred for contralateral approaches.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00194989
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  • 3
    Electronic Resource
    Electronic Resource
    A 12-Month Prospective Study of the Relationship Between Stress Fractures and Bone Turnover in Athletes (1998)
    Springer
    Calcified tissue international 63 (1998), S. 80-85 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Bone turnover — Bone remodeling — Stress fractures — Exercise.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Bone remodeling may be involved in the pathogenesis of stress fractures in athletes. We conducted a 12-month prospective study to evaluate bone turnover in 46 female and 49 male track and field athletes aged 17–26 years (mean age 20.3; SD 2.0) 20 of whom developed a stress fracture. Baseline levels of bone turnover were evaluated in all athletes and monthly bone turnover levels were evaluated in a subset consisting of the 20 athletes who sustained a stress fracture and a matched comparison group who did not sustain a stress fracture. Bone formation was assessed using serum osteocalcin (OC) measured by human immunoradiometric assay and bone resorption by urinary excretion of pyridinium cross-links (Pyr and D-Pyr); high performance liquid chromatography and N-telopeptides of type 1 collagen (NTx) using ELISA assay. Athletes who developed stress fractures had similar baseline levels of bone turnover compared with their nonstress fracture counterparts (P 〉 0.10). Results of serial measurements showed no differences in average levels of Pyr, D-Pyr, or OC in those who developed stress fractures (P= 0.10) compared with the control group. In the athletes with stress fractures, there was also no difference in bone turnover levels prior to or following the onset of bony pain. Our results show that single and multiple measurements of bone turnover are not clinically useful in predicting the likelihood of stress fractures in athletes. Furthermore, there were no consistent temporal changes in bone turnover associated with stress fracture development. However, our results do not negate the possible pathogenetic role of local changes in bone remodeling at stress fracture sites, given the high biological variability of bone turnover markers and the fact that levels of bone turnover reflect the integration of all bone remodeling throughout the skeleton.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002239900493
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  • 4
    Electronic Resource
    Electronic Resource
    Analysis of exceptionally large tremors in two gold mining districts of South Africa (1989)
    Springer
    Pure and applied geophysics 129 (1989), S. 295-307 
    Details
    ISSN: 1420-9136
    Keywords: Large mine tremors ; source parameters ; ground motion parameters ; Klerksdorp mining district ; Carletonville mining district
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract An investigation of ground motion, recorded using broad-band, wide dynamic-range digital seismographs, of large mine tremors from two South African mining districts with different geologic settings, reveals some essential differences in both seismic source and ground motion parameters. In the Klerksdorp district where the strata are offset by major throughgoing normal faults, the largest tremors, with magnitudes ranging as high as 5.2, tend to be associated with slip on these pre-existing faults. Moreover, the seismic source and ground motion parameters are quite similar to those of natural crustal earthquakes. In the Carletonville district, by contrast, where substantial faults do not exist, the large-magnitude tremors appear to result from the failure of relatively intact rock and cause seismic stress drops and ground motion parameters higher than normally observed for natural shocks. Additionally, there appears to be an upper magnitude limit of about 4 in the Carletonville district. Detailed analyses of an exceptionally large event recorded locally from each of these districts serve to highlight these contrasts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00874511
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  • 5
    Electronic Resource
    Electronic Resource
    Changes in the early part of the seismic coda due to localized scatterers: The estimation ofQ in a stope environment (1989)
    Springer
    Pure and applied geophysics 129 (1989), S. 497-511 
    Details
    ISSN: 1420-9136
    Keywords: Seismic coda ; quality factorQ ; localized scatterers ; fractured rock ; stope environment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract A single scattering model was used to analyse the temporary changes in the mean density of scattered waves in a discrete random medium. The model of the mean energy density, originally proposed bySato (1977) for spherical radiation and isotropic scattering, has been modified and applied to a medium in which the scatterers are confined to a specified volume. The time variation of the early part of the mean energy density function for the different source durations was investigated. The dominant effect on the theoretical mean energy density is caused by the specified volume containing scatterers. The duration of the source pulse influences the early part of the coda fort/t 0〈1.2, wheret is the lapse time measured from the source origin time, andt 0is arrival time of the body wave. The analysis of the coda signal of micro-events occurring immediately in front of the face enables us to estimate the size of the fracture zone induced by the stope. The model of the mean energy density of coda for a medium containing scatterers close to the seismic source was used to analyse a large number of events recorded close to an advancing mine face in a deep level gold mine in South Africa. The coda decay rate has two trends: the first, with a steep decay of coda, is produced by a larger deviation of rock parameters and/or larger size of the scatterers; the second trend, which decays more slowly, has the corresponding mean-free path ranging from 20 m to 200 m. The analysis indicates that the rock mass about 15–20 m from the stope contains a large proportion of fractured and blocked rock, which is the source of scattering. The scattering of theS-wave was much stronger and more stable, with the mean-free path varying from 11 m to 45 m. This is due to the shorter wavelength of theS wave in comparison with theP wave. The quality factor for theP coda wave varies from 30 to 100 in the fracture zone of stope and outside this zone it has a value of 300. The quality factor of theS wave varies from 20 to 78 in the equivalent volume. For rock surrounding the stope the ratioQ sp −1 /Q ss −1 varied from 0.31 to 0.69. This suggests that the radii of scatterers are smaller than 3.5 m.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00874521
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  • 6
    Electronic Resource
    Electronic Resource
    The use of the cooling-history of thick intrusive sheets for the study of the secular variation of the earth's magnetic field (1956)
    Springer
    Pure and applied geophysics 35 (1956), S. 49-53 
    Details
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Summary Numerical results are given which show the way in which thc Curie temperature moves inwards from the margin during the cooling of a thick intrusive sheet. The time taken to move from the margin to the centre varies as the square of the thickness of the sheet, being about 6500 years for a sheet 1000 m thick on reasonable assumptions as to the thermal properties of the material. This implies that the secular variation of the Earth's magnetic field over periods of time of 1000 years or more may be studied by measuring the directions of magnetisation at a series of points across the thickness of such a sheet. Some measurements on a Tasmanian sill about 430 m thick of Jurassic or Cretaceous age suggest a change from maximum to minimum inclination in a time of about 200 years. Since the margins of the sill are not available this figure may be considerably in error but the results suggest the general practicability of the method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02122865
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  • 7
    Electronic Resource
    Electronic Resource
    A Diagram Calculus for Certain Canonical Bases (1997)
    Springer
    Communications in mathematical physics 183 (1997), S. 521-532 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract: We introduce a certain cellular algebra $ which is a quotient of the q-Schur algebra $ . This is naturally equipped with a canonical basis which is compatible with Lusztig's canonical bases for certain modules for the quantized enveloping algebra $ . We describe a diagram calculus for $ which makes calculations involving the corresponding canonical bases easy to understand.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002200050041
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  • 8
    Electronic Resource
    Electronic Resource
    Relation between wall teichoic acid content of Bacillus subtilis and efficiency of adsorption of bacteriophages SP 50 and Φ 25 (1982)
    Springer
    Archives of microbiology 133 (1982), S. 318-322 
    Details
    ISSN: 1432-072X
    Keywords: Bacillus subtilis ; Phage ; Receptor ; Teichoic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Efficient adsorption of bacteriophages SP 50 and Φ 25 occurred only to bacilli that contained wall teichoic acid and neither phage bound to phosphate limited bacilli that contained teichuronic acid instead of teichoic acid. Though both phages require the presence of teichoic acid, their receptors are not identical. Efficient binding of phage Φ 25 required the presence of greater proportions of teichoic acid in the wall and the receptor for this phage was destroyed when bacteria or isolated walls were heated at pH 4 whereas the ability of these samples to bind phage SP 50 was unaffected by such treatment. Efficient binding of phage SP 50 was not highly dependant on the presence of glucosyl substituents on the teichoic acid. Such substituents were required for phage Φ 25 binding though their anomeric configuration appeared to be unimportant since the phages bound well to both strains W23 and 168, the wall teichoic acids of which carry glucosyl substituents of opposite anomeric configuration. The differeneces in the nature of the receptors may be of value in the use of the phages as probes for the location and distribution of teichoic acid in the wall.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00521298
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  • 9
    Electronic Resource
    Electronic Resource
    The disposition of four tetracyclines in normal subjects (1976)
    Springer
    European journal of clinical pharmacology 10 (1976), S. 245-250 
    Details
    ISSN: 1432-1041
    Keywords: Tetracyclines ; half life ; volume of distribution ; renal clearance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The disposition of minocycline, tetracycline, doxycycline and oxytetracycline was investigated in four male volunteers after multiple dosing. Values for half life, renal clearance and volume of distribution were calculated and corrected for plasma protein binding. Tetracycline and oxytetracycline have a much larger volume of distribution than minocycline and doxycycline but similar half lives. They give higher tissue levels for equivalent plasma levels. Since their cost per unit dose is much lower they should be the tetracyclines of first choice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558336
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  • 10
    Electronic Resource
    Electronic Resource
    The identical 5' splice-site acceptor mutation in five attenuated APC families from Newfoundland demonstrates a founder effect (1999)
    Springer
    Human genetics 〈Berlin〉 105 (1999), S. 388-398 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Inherited mutations of the APC gene predispose carriers to multiple adenomatous polyps of the colon and rectum and to colorectal cancer. Mutations located at the extreme 5' end of the APC gene, however, are associated with a less severe disease known as attenuated adenomatous polyposis coli (AAPC). Many individuals with AAPC develop relatively few colorectal polyps but are still at high risk for colorectal cancer. We report here the identification of a 5' APC germline mutation in five separately ascertained AAPC families from Newfoundland, Canada. This disease-causing mutation is a single base-pair change (G to A) in the splice-acceptor region of APC intron 3 that creates a mutant RNA without exon 4 of APC. The observation of the same APC mutation in five families from the same geographic area demonstrates a founder effect. Furthermore, the identification of this germline mutation strengthens the correlation between the 5' location of an APC disease-causing mutation and the attenuated polyposis phenotype.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004399900153
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