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  • 1
    Publication Date: 2013-08-24
    Description: A novel H7N9 influenza A virus first detected in March 2013 has since caused more than 130 human infections in China, resulting in 40 deaths. Preliminary analyses suggest that the virus is a reassortant of H7, N9 and H9N2 avian influenza viruses, and carries some amino acids associated with mammalian receptor binding, raising concerns of a new pandemic. However, neither the source populations of the H7N9 outbreak lineage nor the conditions for its genesis are fully known. Using a combination of active surveillance, screening of virus archives, and evolutionary analyses, here we show that H7 viruses probably transferred from domestic duck to chicken populations in China on at least two independent occasions. We show that the H7 viruses subsequently reassorted with enzootic H9N2 viruses to generate the H7N9 outbreak lineage, and a related previously unrecognized H7N7 lineage. The H7N9 outbreak lineage has spread over a large geographic region and is prevalent in chickens at live poultry markets, which are thought to be the immediate source of human infections. Whether the H7N9 outbreak lineage has, or will, become enzootic in China and neighbouring regions requires further investigation. The discovery here of a related H7N7 influenza virus in chickens that has the ability to infect mammals experimentally, suggests that H7 viruses may pose threats beyond the current outbreak. The continuing prevalence of H7 viruses in poultry could lead to the generation of highly pathogenic variants and further sporadic human infections, with a continued risk of the virus acquiring human-to-human transmissibility.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801098/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801098/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lam, Tommy Tsan-Yuk -- Wang, Jia -- Shen, Yongyi -- Zhou, Boping -- Duan, Lian -- Cheung, Chung-Lam -- Ma, Chi -- Lycett, Samantha J -- Leung, Connie Yin-Hung -- Chen, Xinchun -- Li, Lifeng -- Hong, Wenshan -- Chai, Yujuan -- Zhou, Linlin -- Liang, Huyi -- Ou, Zhihua -- Liu, Yongmei -- Farooqui, Amber -- Kelvin, David J -- Poon, Leo L M -- Smith, David K -- Pybus, Oliver G -- Leung, Gabriel M -- Shu, Yuelong -- Webster, Robert G -- Webby, Richard J -- Peiris, Joseph S M -- Rambaut, Andrew -- Zhu, Huachen -- Guan, Yi -- 092807/Wellcome Trust/United Kingdom -- 095831/Wellcome Trust/United Kingdom -- 260864/European Research Council/International -- BB/E009670/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- HHSN266200700005C/AI/NIAID NIH HHS/ -- HSN266200700005C/PHS HHS/ -- England -- Nature. 2013 Oct 10;502(7470):241-4. doi: 10.1038/nature12515. Epub 2013 Aug 21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Joint Influenza Research Centre (SUMC/HKU), Shantou University Medical College, Shantou 515041, China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23965623" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chickens ; China ; Ducks ; Genes, Viral/genetics ; Humans ; Influenza A Virus, H7N7 Subtype/classification/genetics ; Influenza A Virus, H9N2 Subtype/classification/genetics ; Influenza A virus/*classification/*genetics ; Influenza in Birds/transmission/virology ; Influenza, Human/transmission/*virology ; Molecular Sequence Data ; *Phylogeny ; Reassortant Viruses/classification/genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2013-05-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zhang, Fusuo -- Chen, Xinping -- Vitousek, Peter -- England -- Nature. 2013 May 2;497(7447):33-5. doi: 10.1038/497033a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Resources, Environment and Food Security, China Agricultural University, Beijing, China. zhangfs@cau.edu.cn〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23636381" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture/economics/methods/*statistics & numerical data/*trends ; Biomass ; China ; Crops, Agricultural/metabolism/radiation effects ; Ecosystem ; Fertilizers/adverse effects/utilization ; Food Supply/economics/*methods/*statistics & numerical data ; Food, Genetically Modified ; Models, Biological ; Plants, Genetically Modified ; Research/economics ; Soil/analysis/chemistry ; Sunlight ; Water Supply/statistics & numerical data
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2014-09-05
    Description: Agriculture faces great challenges to ensure global food security by increasing yields while reducing environmental costs. Here we address this challenge by conducting a total of 153 site-year field experiments covering the main agro-ecological areas for rice, wheat and maize production in China. A set of integrated soil-crop system management practices based on a modern understanding of crop ecophysiology and soil biogeochemistry increases average yields for rice, wheat and maize from 7.2 million grams per hectare (Mg ha(-1)), 7.2 Mg ha(-1) and 10.5 Mg ha(-1) to 8.5 Mg ha(-1), 8.9 Mg ha(-1) and 14.2 Mg ha(-1), respectively, without any increase in nitrogen fertilizer. Model simulation and life-cycle assessment show that reactive nitrogen losses and greenhouse gas emissions are reduced substantially by integrated soil-crop system management. If farmers in China could achieve average grain yields equivalent to 80% of this treatment by 2030, over the same planting area as in 2012, total production of rice, wheat and maize in China would be more than enough to meet the demand for direct human consumption and a substantially increased demand for animal feed, while decreasing the environmental costs of intensive agriculture.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, Xinping -- Cui, Zhenling -- Fan, Mingsheng -- Vitousek, Peter -- Zhao, Ming -- Ma, Wenqi -- Wang, Zhenlin -- Zhang, Weijian -- Yan, Xiaoyuan -- Yang, Jianchang -- Deng, Xiping -- Gao, Qiang -- Zhang, Qiang -- Guo, Shiwei -- Ren, Jun -- Li, Shiqing -- Ye, Youliang -- Wang, Zhaohui -- Huang, Jianliang -- Tang, Qiyuan -- Sun, Yixiang -- Peng, Xianlong -- Zhang, Jiwang -- He, Mingrong -- Zhu, Yunji -- Xue, Jiquan -- Wang, Guiliang -- Wu, Liang -- An, Ning -- Wu, Liangquan -- Ma, Lin -- Zhang, Weifeng -- Zhang, Fusuo -- England -- Nature. 2014 Oct 23;514(7523):486-9. doi: 10.1038/nature13609. Epub 2014 Sep 3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉1] College of Resources &Environmental Sciences, China Agricultural University, Beijing 100193, China [2]. ; College of Resources &Environmental Sciences, China Agricultural University, Beijing 100193, China. ; Department of Biology, Stanford University, Stanford, California 94305, USA. ; Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China. ; College of Resources &Environmental Sciences, Agricultural University of Hebei, Baoding 071001, China. ; College of Agronomy, Shandong Agricultural University, Tai'an 271000, China. ; Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China. ; Key Laboratory of Crop Genetics and Physiology of Jiangsu Province, Yangzhou University, Yangzhou 225009, China. ; State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau, Northwest Agriculture and Forestry University, Yangling 712100, China. ; College of Resources &Environmental Sciences, Jilin Agricultural University, Changchun 130118, China. ; Institute of Agricultural Environment and Resource, Shanxi Academy of Agricultural Sciences, Taiyuan 030031, China. ; College of Resources &Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China. ; Research Center of Agricultural Environment &Resources, Jilin Academy of Agricultural Sciences, Changchun 130033, China. ; College of Resources &Environmental Sciences, Henan Agricultural University, Zhengzhou 450000, China. ; Northwest Agriculture and Forestry University, Yangling 712100, China. ; College of Plant Science &Technology, Huazhong Agricultural University, Wuhan 430070, China. ; Crop Physiology, Ecology &Production Center, Hunan Agricultural University, Changsha 410128, China. ; Soil &Fertilizer Research Institute, Anhui Academy of Agricultural Sciences, Hefei 230031, China. ; College of Resources &Environmental Sciences, Northeast Agricultural University, Harbin 150030, China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25186728" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture/*methods ; Animal Feed ; China ; Edible Grain/*growth & development/*supply & distribution ; *Environment ; Fertilizers/utilization ; Greenhouse Effect/statistics & numerical data ; Nitrogen/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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