ISSN:
1420-9071
Keywords:
TRH
;
TRH analogues
;
thermogenesis
;
brown adipose tissue
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Acute or chronic injection of RX 77368 (a TRH analogue; 1 mg/kg s.c.) stimulated oxygen consumption (VO2) and brown adipose tissue activity in the rat, and decreased weight gain Other TRH analogues (CG 3509, RGH 2202) and TRH itself also stimulated VO2. These thermogenic actions are probably mediated centrally by stimulation of sympathetic outflow to brown fat.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01960238
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