Publication Date:
1978-06-02
Description:
Inoculation of the buffy coat of blood from guinea pigs infected with Creutzfeldt-Jakob disease resulted in passage of this disease to recipient animals. This demonstrates that there is a viremia in experimental Creutzfeldt-Jakob disease. These findings suggest that the hematogenous route may be implicated in the human infection and that the disease may possibly be transmitted by blood transfusions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Manuelidis, E E -- Gorgacs, E J -- Manuelidis, L -- New York, N.Y. -- Science. 1978 Jun 2;200(4345):1069-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/349691" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Blood/*microbiology
;
Creutzfeldt-Jakob Syndrome/blood/*microbiology/transmission
;
*Disease Models, Animal
;
Guinea Pigs
;
Humans
;
Leukocytes/microbiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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