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  • 1975-1979  (9)
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  • 1
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    Results of eye examination (1975)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-16
    Beschreibung: Five pocket mice (Perognathus longimembris) were flown on Apollo XVII, and four survived. All the eyes, except one eye from the dead flight mouse, were examined histologically. In the four surviving mice, a total of five cosmic-ray particles which had registered in the subscalp particle detectors had trajectories that intersected the eyes. Four of them (Z = 6.9 for three of the particles and Z greater than or equal to 10 for the fourth) most likely went through the head before reaching the particle detector, while the thindown direction of the fifth (Z greater than or equal to 10) was not determinable. The retinas of the flight animals were found free from histological alterations such as might have been expected from encounters with cosmic-ray particles.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 2
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    Cosmic ray particle dosimetry and trajectory tracing (1975)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-16
    Beschreibung: Five pocket mice (Perognathus longimembris) were flown on Apollo XVII, each with a solid-state (plastic) nuclear track detector implanted beneath its scalp. The subscalp detectors were sensitive to HZE cosmic ray particles with a LET greater than or approximately equal to 0.15 million electron volts per micrometer (MeV/micron). A critical aspect of the dosimetry of the experiment involved tracing individual particle trajectories through each mouse head from particle tracks registered in the individual subscalp detectors, thereby establishing a one-to-one correspondence between a trajectory location in the tissue and the presence or absence of a lesion. The other major aspect was the identification of each registered particle. An average of 16 particles with Z greater than or equal to 6 and 2.2 particles with Z greater than or equal to 20 were found per detector. The track density, 29 tracks/sq cm, when adjusted for detection volume, was in agreement with the photographic emulsion data from an area dosimeter located next to the flight package.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 3
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    Launch, flight, and recovery (1975)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-16
    Beschreibung: The final phase to fly five pocket mice in the Apollo XVII command module was carried out at the NASA Kennedy Space Center. Upon completion of the 13-d space flight, the package was removed from the spacecraft and, after having been purged with an oxygen-helium gas mixture, was flown to American Samoa. Four of the five mice were recovered alive from the package. Analysis of the mouse that died during the flight revealed several factors that could have contributed to its death, the chief of which was massive hemorrhage in its middle ear cavities.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 4
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    Preflight studies on tolerance of pocket mice to oxygen and heat. III - Effects on eyes (1975)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-16
    Beschreibung: A study was made of the eyes of eight pocket mice exposed to oxygen at partial pressures of 8, 10, or 12 psi over a period of 7 d. At the termination of the exposure, the animals were decompressed to sea-level O2, either immediately or over a period of 30, 60, or 90 min. No pathological changes were found in any of the eyes, except in the retina of one of the animals exposed to 12 psi O2. Here, only a single rod photoreceptor was found damaged, an observation not regarded as significant. Hence, an oxygen partial pressure as high as 12 psi in the canister in which pocket mice were expected to fly on Apollo XVII would probably have no deleterious effect on the eyes of the animals.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 5
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    Ultrastructural changes in tracheal epithelial cells exposed to oxygen (1977)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-17
    Beschreibung: White albino rats were sacrificed after 24, 36, 48, 72, and 96 h of exposure to 100% O2 at 1 atm. Tissue was prepared for the scanning electron microscope (SEM) by Critical Point Drying and for the transmission electron microscope (TEM) by plastic embedding. Scanning microscopy showed a loss of microvilli after 48 h of exposure. Cilia appeared relatively normal with SEM, but TEM revealed changes in the outer membrane. In TEM, nonciliated cells appeared swollen and often encroached on the ciliated cells. A heavy mucous blanket remained even after processing. All the changes observed that are induced by oxygen exposure contribute to mucostasis, reducing and/or halting mucociliary clearance.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 6
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    A study of axonal degeneration in the optic nerves of aging mice (1978)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-17
    Beschreibung: The optic nerves of C57BL/6J mice ranging from 3 to 30 months were examined by electron microscopy. At all ages investigated, optic nerve axons contained enlarged mitochondria with abnormal cristae. With increasing age, a large number of necrotic axons were observed and were in the process of being phagocytized. The abnormal mitochondria may represent preliminary changes that eventually lead to necrosis of the axon.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Materialart: Age; 1; Apr. 197
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 7
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    Modification of a Kowa RC-2 fundus camera for self-photography without the use of mydriatics (1979)
    In:  Other Sources
    Details
    Publikationsdatum: 2011-08-17
    Beschreibung: Research on retinal circulation during space flight required the development of a simple technique to provide self monitoring of blood vessel changes in the fundus without the use of mydriatics. A Kowa RC-2 fundus camera was modified for self-photography by the use of a bite plate for positioning and cross hairs for focusing the subject's retina relative to the film plane. Dilation of the pupils without the use of mydriatics was accomplished by dark-adaption of the subject. Pictures were obtained without pupil constriction by the use of a high speed strobe light. This method also has applications for clinical medicine.
    Schlagwort(e): INSTRUMENTATION AND PHOTOGRAPHY
    Materialart: Brain Research Bulletin; 4; 1979
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 8
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    Effects of high-LET neon /Ne-20/ particle radiation on the brain, eyes and other head structures of the pocket mouse - A histological study (1979)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-06-27
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Materialart: International Journal of Radiation Biology; 35; 1, 19; 1979
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 9
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    Cosmic ray effects on the eyes of rats flown on Cosmos no. 782, Experiment K-007 (1978)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-06-27
    Beschreibung: A study was undertaken to determine if, and to what extent, pathological damage results from high-energy particles (HZE) transversing the eye. Light flashes experienced by space travellers indicate that HZE do indeed pass through and activate the retina, but whether actual biological damage occurs has not been investigated thoroughly. Thus, autopsies were performed on the eyes of rats which has been flown in Cosmos 782 satellite for 19.5 days. Comparisons with a control sample subjected to 1000 rads of Ar and Ne radiation show that pathological damage, when it occurs, affects the nucleus of the retina; simple light flashes are not thought to indicate a pathology, and result from activation of (but not damage to) the retina's outer segments.
    Schlagwort(e): LIFE SCIENCES (GENERAL)
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
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