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  • STRUCTURAL MECHANICS  (3)
  • Female  (1)
  • Biochemistry and Biotechnology
  • FLUID MECHANICS AND HEAT TRANSFER
  • 1975-1979  (4)
  • 1
    Publication Date: 1979-07-13
    Description: Human erythrocytes have specific insulin receptors. When studied in an insulin radioreceptor assay, erythrocytes from adult-onset, nonobese diabetic subjects bound at least 42 percent less insulin than the normal subjects at insulin concentrations from 0.1 to 100 nanograms per milliliter. The diabetic subjects had 190 insulin receptor sites per cell as compared with the 380 insulin receptor sites per cell for the normal subjects. The deficit of insulin binding in the diabetic subject was thus associated with a fewer number of insulin binding sites per cell with little or no change in affinity. The erythrocyte is a readily available cell for the evaluation of cellular insulin receptor activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Robinson, T J -- Archer, J A -- Gambhir, K K -- Hollis, V W Jr -- Carter, L -- Bradley, C -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):200-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451590" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Aged ; Diabetes Mellitus/*blood/metabolism ; Erythrocyte Membrane/*metabolism ; Erythrocytes/*metabolism ; Female ; Humans ; Insulin/metabolism ; Male ; Middle Aged ; Receptor, Insulin/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2006-06-13
    Description: A continuing effort to develop a comprehensive capability for thermal-structural analysis and automated design (sizing) is reviewed. A principal role in the activity is played by the finite element program SPAR which contains both an efficient structural and thermal analysis capability. The benefit of having thermal and structural analyses in the same finite element program is illustrated by the application of SPAR to design calculations for the National Transonic Facility - a cryogenic wind tunnel under construction at Langley. Some experience with large-scale thermal structural analysis problems, particularly the space shuttle orbiter, has led to the identification of some analysis needs. Those needs include automated model generation and data output for lumped parameter thermal analysis, faster solution methods for nonlinear transient heat transfer, automated interpolation of temperature data from a thermal finite element model to a dissimilar structural finite model, and automated techniques to identify the times at which the critical combinations of transient heating and loads occur on a structure.
    Keywords: STRUCTURAL MECHANICS
    Type: Recent Advan. in Structures for Hypersonic Flight, Pt.2; p 897-941
    Format: text
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  • 3
    Publication Date: 2019-06-27
    Description: A multilayered finite element with bending-extensional coupling is evaluated for: (1) buckling of general laminated plates; (2) thermal stresses of laminated plates cured at elevated temperatures; (3) displacements of a bimetallic beam; and (4) displacement and stresses of a single-cell box beam with warped cover panels. Also, displacements and stresses for flat and spherical orthotropic and anisotropic segments are compared with results from higher order plate and shell finite-element analyses.
    Keywords: STRUCTURAL MECHANICS
    Type: NASA-TP-1236 , L-12113
    Format: application/pdf
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  • 4
    Publication Date: 2019-07-13
    Description: Two methods for determining stresses and internal forces in geometrically nonlinear structural analysis are presented. The simplified approach uses the mid-deformed structural position to evaluate strains when rigid body rotation is present. The important feature of this approach is that it can easily be used with a general-purpose finite-element computer program. The refined approach uses element intrinsic or corotational coordinates and a geometric transformation to determine element strains from joint displacements. Results are presented which demonstrate the capabilities of these potentially useful approaches for geometrically nonlinear structural analysis.
    Keywords: STRUCTURAL MECHANICS
    Type: AIAA PAPER 79-0746 , Structures, Structural Dynamics, and Materials Conference; Apr 04, 1979 - Apr 06, 1979; St. Louis, MO
    Format: text
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