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  • 1
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    Long-latency "subthreshold" collicular responses to the constant-frequency components emitted by a bat (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-01
    Description: A previously undescribed response pattern has been observed in certain single units in the posterior colliculus of Pteronotus suapurensis. These units, constituting about one-third of those tuned to the region of the dominant constant-frequency (CF) components of the orientation sounds, respond to a tone pip with a burst of spikes at a latency of 3 to 6 milliseconds, within the frequency-intensity domain of a normal V-shaped response area. In these units, however, as intensity is dropped below threshold for this response, a response of 5-to 10-milliseconds longer latency appears and persists throughout another 10 to 30 decibels of attenuation. These late responses can be very vigorous, are sharply tuned to frequencies at or just above the CF components of the signal, and are often strongest and of lowest threshold at stimulus durations of 1.5 to 3 milliseconds--approximately the duration of the CF component. These properties imply that the late responses are concerned with analysis of the CF components of echoes, apparently in ways not as prominent in other bats.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Grinnell, A D -- Brown, P -- New York, N.Y. -- Science. 1978 Dec 1;202(4371):996-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715456" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Auditory Pathways/*physiology ; Auditory Perception/*physiology ; Auditory Threshold/physiology ; Chiroptera/*physiology ; Echolocation/*physiology ; Inferior Colliculi/*physiology ; Orientation/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Rapid light-induced changes in near infrared transmission of rods in Bufo marinus (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-08
    Description: Rapid transient changes in axial transmission of near infrared light through the outer segments of retinal rods of Bufo marinus are induced by illumination. The reasons for these changes are not clear. The changes in optical transmission may be useful in the study of photoreceptor function. However, the study of photoreceptor functions through the use of indicator dyes may be confounded by the intrinsic light-induced changes of optical properties of the photoreceptor cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harary, H H -- Brown, J E -- Pinto, L H -- New York, N.Y. -- Science. 1978 Dec 8;202(4372):1083-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/102035" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bufo marinus ; Dose-Response Relationship, Radiation ; In Vitro Techniques ; Infrared Rays ; *Light ; Photoreceptor Cells/physiology/*radiation effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    Mitochondrial DNA analyses and the origin and relative age of parthenogenetic lizards (genus Cnemidophorus) (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-23
    Description: Morphological, karyological, and allozyme analyses indicate that the parthenogenetic lizards Cnemidophorus neomexicanus and diploid C. tesselatus are hybrids formed, respectively, by crosses involving the bisexual species C. tigris and C. inornatus, and C. tigris and C. septemvittatus. Mitochondrial DNA, which is inherited maternally, was obtained from each of these species. Analyses of the mitochondrial DNA's and their restriction endonuclease digestion products by electron microscopy and agarose gel electrophoresis support the hybridization hypothesis by indicating that C. tigris (specifically the subspecies marmoratus) was the maternal parent species for both C. neomexicanus and C. tesselatus. Furthermore, these data imply that these two parthenogenetic species are younger than some races of C. tigris.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, W M -- Wright, J W -- New York, N.Y. -- Science. 1979 Mar 23;203(4386):1247-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424751" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; DNA Restriction Enzymes/metabolism ; DNA, Mitochondrial/*genetics ; Lizards/*genetics ; *Parthenogenesis ; Reproduction ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    A direct role of dopamine in the rat subthalamic nucleus and an adjacent intrapeduncular area (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: The subthalamic nucleus, a clinically important component of the extrapyramidal motor system, and a lateral area extending into the peduncle contain catecholamine terminals and dopamine receptors coupled to adenylate cyclase. In addition, dopamine agonists administered in vivo enhance glucose utilization in the region. Thus, neuronal function in this region is directly affected by dopamine and dopaminergic drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, L L -- Markman, M H -- Wolfson, L I -- Dvorkin, B -- Warner, C -- Katzman, R -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1416-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505015" target="_blank"〉PubMed〈/a〉
    Keywords: Adenylyl Cyclases/metabolism ; Animals ; Brain Mapping ; Catecholamines/pharmacology ; Dopamine/pharmacology ; Enzyme Activation/drug effects ; Extrapyramidal Tracts/*metabolism/ultrastructure ; Glucose/metabolism ; Male ; Mesencephalon/*metabolism ; Neurons/metabolism ; Rats ; Receptors, Dopamine/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Localization of primate calls by old world monkeys (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-25
    Description: Monkeys (Macaca) were trained by operant conditioning techniques to report the minimum detectable change in location of a sound in space, and were tested with a series of recorded coo or clear call vocalizations. Acuity of localization varied from approximately 4 degrees to 15 degrees and was a function of the magnitude of the change in pitch (frequency modulation) of the different clear calls.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, C H -- Beecher, M D -- Moody, D B -- Stebbins, W C -- New York, N.Y. -- Science. 1978 Aug 25;201(4357):753-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/97785" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Auditory Perception/*physiology ; Haplorhini ; Macaca/*physiology ; Orientation/*physiology ; Pitch Discrimination/physiology ; Vocalization, Animal/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Ethanol embryotoxicity: direct effects on mammalian embryos in vitro (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: Exposure to ethanol retards growth and differentiation in cultured rat embryos during organogenesis. The development of untreated embryos is indistinguishable from growth in utero. These data suggest that the hypoplastic features of children born to chronically alcoholic mothers are due, at least in part, to a direct action of ethanol, which causes reduced embryonic cellular proliferation early in gestation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, N A -- Goulding, E H -- Fabro, S -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):573-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/573922" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Dose-Response Relationship, Drug ; Ectogenesis/*drug effects ; Embryo, Mammalian/*drug effects ; Ethanol/*toxicity ; Female ; Fetal Growth Retardation/chemically induced ; Pregnancy ; Rats ; *Teratogens
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Experimental allergic neuritis induced by sensitization with galactocerebroside (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: Thirteen of 31 rabbits immunized repeatedly with bovine brain galactocerebroside developed experimental allergic neuritis, manifested by flaccid paresis and hypesthesia of four limbs, 2 to 11 months after the initial inoculation. Electrophysiological studies revealed multifocal conduction block of peripheral nerves. Perivenular demyelinative lesions associated with phagocytic mononuclear cells occurred in spinal ganglia, roots, and less frequently in distal nerves.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Saida, T -- Saida, K -- Dorfman, S H -- Silberberg, D H -- Sumner, A J -- Manning, M C -- Lisak, R P -- Brown, M J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1103-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451555" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Autoantibodies/analysis ; Autoimmune Diseases/*immunology ; Cerebrosides/*immunology ; Demyelinating Diseases/*immunology/pathology ; Galactosylceramides/*immunology ; Male ; Myelin Sheath/physiopathology ; Neural Conduction ; Neuritis/*immunology/pathology/physiopathology ; Rabbits
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Cerebral glucose utilization: local changes during and after recovery from spreading cortical depression (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-12
    Description: Cerebral glucose utilization is markedly increased in most areas of the cerebral cortex and reduced in many subcortical structures during spreading cortical depression. During recovery, cortical glucose utilization is still elevated, but the increased metabolic activity is distributed in columns running perpendicularly through the cortex.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shinohara, M -- Dollinger, B -- Brown, G -- Rapoport, S -- Sokoloff, L -- New York, N.Y. -- Science. 1979 Jan 12;203(4376):188-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758688" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*metabolism ; Brain Mapping ; *Cortical Spreading Depression/drug effects ; Deoxyglucose/metabolism ; Energy Metabolism ; Glucose/*metabolism ; Male ; Potassium Chloride/pharmacology ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-31
    Description: Depletion of dopamine in a circumscribed area of association cortex in rhesus monkeys produces an impairment in spatial delayed alternation performance nearly as severe as that caused by surgical ablation of the same area. This behavioral deficit can be pharmacologically reversed with dopamine agonists such as L-dopa and apomorphine. These data provide direct evidence that dopamine plays an important role in a specific cortical function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brozoski, T J -- Brown, R M -- Rosvold, H E -- Goldman, P S -- New York, N.Y. -- Science. 1979 Aug 31;205(4409):929-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/112679" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apomorphine/pharmacology ; Behavior, Animal/drug effects/physiology ; Cerebral Cortex/*physiology ; Cognition/drug effects/*physiology ; Dihydroxyphenylalanine/analogs & derivatives/pharmacology ; Dopamine/*physiology ; Dose-Response Relationship, Drug ; Haplorhini ; Levodopa/pharmacology ; Macaca mulatta ; Norepinephrine/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Cellular applications of 31P and 13C nuclear magnetic resonance (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: High-resolution nuclear magnetic resonance (NMR) studies of cells and purified mitochondria are discussed to show the kind of information that can be obtained in vivo. In suspensions of Escherichia coli both phosphorus-31 and carbon-13 NMR studies of glycolysis and bioenergetics are presented. In rat liver cells the pathways of gluconeogenesis from carbon-13-labeled glycerol are followed by carbon-13 NMR. In the intact liver cells cytosolic and mitochondrial pH's were separately measured by phosphorus-31 NMR. In purified mitochondria the internal and external concentrations of inorganic phosphate, adenosine diphosphate, and adenosine triphosphate were determined by phosphorus-31 NMR while the pH difference across the membrane was measured simultaneously.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shulman, R G -- Brown, T R -- Ugurbil, K -- Ogawa, S -- Cohen, S M -- den Hollander, J A -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):160-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/36664" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Diphosphate/*metabolism ; Adenosine Triphosphate/*metabolism ; Animals ; Carbon Isotopes ; Escherichia coli/metabolism ; Hydrogen-Ion Concentration ; Kinetics ; Liver/metabolism ; Magnetic Resonance Spectroscopy/*methods ; Mitochondria/metabolism ; Phosphates/*metabolism ; Phosphorus Isotopes ; Rats ; Sugar Phosphates/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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