Publication Date:
1982-09-17
Description:
Melanization was induced in some cells of a goldfish tumor cell line (GEM-81) by cultivating the cells in autologous serum. The melanized cells continued to proliferate in vitro and several clones were isolated that differed with respect to cell morphology and intracellular distribution of pigment. Some of the clones consisted of cells able to translocate their melanosomes in response to epinephrine, melatonin, or adenosine 3', 5'-monophosphate.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matsumoto, J -- Lynch, T J -- Grabowski, S M -- Taylor, J D -- Tchen, T T -- AM13724/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1982 Sep 17;217(4565):1149-51.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6287577" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Cell Differentiation
;
Clone Cells/cytology
;
Cyclic AMP/pharmacology
;
Epinephrine/pharmacology
;
Goldfish
;
Melanins/*biosynthesis
;
Melanophores/drug effects/*ultrastructure
;
Melatonin/pharmacology
;
Movement/drug effects
;
Neoplasms, Experimental/*pathology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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