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  • LUNAR AND PLANETARY EXPLORATION  (596)
  • Animals  (448)
  • 1980-1984  (1,043)
  • 1935-1939  (1)
  • 1
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    Pioneer Venus radar results - Geology from images and altimetry (1980)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: An unimodal distribution of relief for Venus was obtained from the Pioneer Venus altimetry measurements. The 'upland' rolling plains constituting 65% of the surface show dark circular lava-filled impact basins; highlands in the 8% of the area comprise Ishtar Terra and Aphrodite Terra; and the lowlands consist of crudely circular surfaces with low relief within the highlands. The complex ridge-and-trough regions east of Ishtar Terra and in the southern Aphrodite Terra may be due to large-scale crustal motions.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Journal of Geophysical Research; 85; Dec. 30
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    Activation of the transforming potential of a normal cell sequence: a molecular model for oncogenesis (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-22
    Description: The molecularly cloned, long terminal repeat (LTR) of the Moloney sarcoma virus (M-MSV) provirus has been covalently linked to c-mos, the cellular homolog of the M-MSV-specific sequence, v-mos. These newly constructed clones lack any M-MSV-derived sequences other than the LTR, but in DNA transfection assays they transform cells as efficiently as cloned subgenomic M-MSV fragments containing both v-mos and LTR. Cells transformed by LTR:c-mos hybrid molecules contain additional copies of mos DNA, and several size classes of polyadenylated RNA's with sequence homology to mos. The activation of the transforming potential of c-mos by the proviral LTR suggests a model whereby LTR-like elements could activate other normal cell sequences with oncogenic potential.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Blair, D G -- Oskarsson, M -- Wood, T G -- McClements, W L -- Fischinger, P J -- Vande Woude, G G -- New York, N.Y. -- Science. 1981 May 22;212(4497):941-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233190" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Transformation, Viral ; Cells, Cultured ; DNA, Recombinant ; Defective Viruses/genetics ; Gene Expression Regulation ; *Genes, Viral ; Mice ; Moloney murine leukemia virus/*genetics ; Nucleic Acid Hybridization ; Operon ; Plasmids
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Radio science investigations of the Saturn system with Voyager 1 - Preliminary results (1981)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Analyses of Voyager 1 radio occultation measurements of the Saturn atmosphere near 75 deg south latitude and of the Titan equatorial atmosphere are presented. Molecular nitrogen appears to be the primary atmospheric constituent of Titan, whose clouds are probably methane ice. Solar abundance considerations of the data suggest large quantities of surface methane near its triple-point temperature, so that the three phases of methane could play a role on Titan analogous to that of water on earth. Ionospheric electron concentration and plasma scale height for the Saturn polar cap and monochromatic attenuation of the Saturn rings are also considered, along with radio tracking figures for the masses of two moons, Rhea and Titan.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Science; 212; Apr. 10
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    NASA TECHNICAL REPORTS
  • 4
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    Radio science with Voyager 2 at Saturn - Atmosphere and ionosphere and the masses of Mimas, Tethys, and Iapetus (1982)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Results of Voyager 2 radio occultation studies of the atmosphere and ionosphere of Saturn and radio tracking determinations of the masses of Mimas, Tethys, and Iapetus are presented. Measurement of received signal frequency for signals of 3.6 and 13 cm wavelength during Voyager occultation immersion at 36.5 deg N and emmersion at 31 deg S reveal atmospheric temperatures of 143 K at the 1.2 bar level, falling to 82 K at the tropopause at about 70 mbar and rising to about 140 K at the tropopause at about 70 mbar and rising to about 140 K at the 1-mbar pressure level in the stratosphere. Peak electron concentrations of 17,000 and 6400/cu cm are found in the predawn and late afternoon locations, respectively, with topside plasma scale heights of 260-1100 km and 1000 km. Direct measurements of the masses of Tethys and Iapetus yield values of 7.55 and 18.8 x 10 to the 20th kg respectively, and an implied mass of 0.455 x 10 to the 20 kg for Mimas. Results suggest that satellite density tends to decrease with increasing orbital radius, and imply that the intermediate-sized satellites of Saturn may represent objects with differing relative amounts of water, ammonia and methane ices. The apparent low density of Iapetus may then be explained by a large hydrocarbon content.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Science; 215; Jan. 29
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    NASA TECHNICAL REPORTS
  • 5
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    Pioneer Venus radar results - Altimetry and surface properties (1980)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: A topographic map of 93% of the Venus globe was depicted by the radar altimeter of the Pioneer Venus orbiter with a resolution better than 150 km. Extremes in relief expressed as a center-of-mass-to-surface radius extend from 6049 to 6062 km; the elevated terrain is dominated by a massive equatorial area equal in size to South America. The distribution of average meter-scale surface slopes is determined for the same regions in the 1 to 10 deg range; elevated areas have higher slopes, so that most features observed in the earth-based images are also evident in the vertical-incidence spacecraft measurements.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Journal of Geophysical Research; 85; Dec. 30
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    NASA TECHNICAL REPORTS
  • 6
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    Functional insertion of an Alu type 2 (B2 SINE) repetitive sequence in murine class I genes (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-23
    Description: The regulation of expression of the family of MHC (major histocompatibility complex) class I genes is complex. Sequence analysis has revealed that class I genes from the H-2D subregion of the MHC (which includes the D and L genes) differ from the class I gene from the H-2K subregion (the K gene) by the insertion of a type 2 Alu-like repetitive element (the murine B2 sequence) within the 3' noncoding region of the D and L genes. The consequence of this insertion in the D and L genes is the introduction of a novel polyadenylation signal, which is preferentially used over the more distal signal, the analog of that found in the K gene. The insertion of the type 2 Alu-like sequence results in a change in the preferred site for endonucleolytic cleavage which is necessary for generating a correct 3' terminus for polyadenylation. The data demonstrate that the type 2 Alu-like sequence has a function; the data also suggest a possible regulatory role of this sequence in the expression of class I genes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kress, M -- Barra, Y -- Seidman, J G -- Khoury, G -- Jay, G -- AI 19148/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 23;226(4677):974-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6095445" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosome Deletion ; *Cloning, Molecular ; DNA/*metabolism ; DNA Restriction Enzymes ; *DNA Transposable Elements ; Genes, MHC Class II ; Genetic Linkage ; *Major Histocompatibility Complex ; Mice ; Protein Biosynthesis ; Repetitive Sequences, Nucleic Acid
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Reduction of the isoproterenol-induced alterations in cardiac adenine nucleotides and morphology by ribose (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-18
    Description: Continuous intravenous infusion of ribose (200 milligrams per kilogram per hour) for 24 hours induced a marked stimulation of cardiac adenine nucleotide biosynthesis in unanesthetized and unrestrained rats that had been treated with isoproterenol subcutaneously (25 milligrams per kilogram). The diminution of adenine nucleotides characteristic for the action of high doses of isoproterenol was entirely prevented, and the incidence of the isoproterenol-induced myocardial cell damage was significantly reduced when ribose was administered. These results support the view that depletion of adenine nucleotides is involved in the development of cardiac necrosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zimmer, H G -- Ibel, H -- Steinkopff, G -- Korb, G -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):319-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350664" target="_blank"〉PubMed〈/a〉
    Keywords: Adenine Nucleotides/*metabolism ; Animals ; Female ; Heart/*drug effects ; Isoproterenol/*antagonists & inhibitors/toxicity ; Myocardium/*metabolism/pathology ; Rats ; Ribose/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Interference with dimethylhydrazine induction of colon tumors in mice by epsilon-aminocaproic acid (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-05-28
    Description: The antifibrinolytic agent epsilon-aminocaproic acid given in the drinking water to Swiss ICR/Ha mice significantly counteracted the appearance of colorectal tumors induced by 21 weekly infections of 1,2-dimethylhydrazine. The drug affected both the number and the location of the tumors and, in some animals, altogether prevented their appearance. The low concentrations of epsilon-aminocaproic acid in the plasma of four control mice given the agent labeled with carbon-14 for 3 days suggest that the effect may depend not on inhibition of plasminogen activator activity, but on interference with the binding of some substance to the strong lysine binding site of plasminogen.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Corasanti, J G -- Hobika, G H -- Markus, G -- New York, N.Y. -- Science. 1982 May 28;216(4549):1020-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6805074" target="_blank"〉PubMed〈/a〉
    Keywords: Adenocarcinoma/*chemically induced ; Aminocaproates/*pharmacology ; Animals ; Colonic Neoplasms/*chemically induced ; Dimethylhydrazines/*antagonists & inhibitors ; Female ; Male ; Methylhydrazines/*antagonists & inhibitors ; Mice ; Neoplasms, Experimental/chemically induced ; Plasminogen/metabolism ; Plasminogen Activators/antagonists & inhibitors ; Plasminogen Inactivators ; Protein Binding
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Suppressor T cell action inhibits the expression of an excluded immunoglobulin gene (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-24
    Description: Cells of the murine plasmacytoid line MOPC-315 synthesize two distinct immunoglobulin light chains: a normal lambda II protein, which is incorporated into secretory and surface-bound immunoglobulin, and a truncated, nonfunctional lambda I protein found only in the cytoplasm. Idiotype-specific suppressor T lymphocytes selectively inhibit the expression of both lambda II- and lambda I-specific messenger RNA by MOPC-315 cells. This finding demonstrates that phenotypically excluded light chain genes can be subject to immunoregulatory control and suggests that the expression of divergent lambda isotypes may be coordinately regulated in immunoglobulin-secreting cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parslow, T G -- Milburn, G L -- Lynch, R G -- Granner, D K -- AM25295/AM/NIADDK NIH HHS/ -- CA28848/CA/NCI NIH HHS/ -- CA32275/CA/NCI NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1983 Jun 24;220(4604):1389-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6222474" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; *Gene Expression Regulation ; Immunoglobulin Light Chains/genetics ; Immunoglobulin lambda-Chains/genetics ; Immunoglobulins/*genetics ; Mice ; Mice, Inbred BALB C ; Plasmacytoma/genetics/immunology ; RNA, Messenger/biosynthesis ; T-Lymphocytes, Regulatory/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    Endogenous opiates mediate radiogenic behavioral change (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-10
    Description: Exposure of C57BL/6J mice to ionizing radiation caused stereotypical locomotor hyperactivity similar to that produced by morphine. Naloxone administration prevented this radiation-induced behavioral activation. These results support the hypothesis that endorphins are involved in some aspects of radiogenic behavioral change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mickley, G A -- Stevens, K E -- White, G A -- Gibbs, G L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1185-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857244" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/drug effects/physiology/*radiation effects ; Dose-Response Relationship, Radiation ; Endorphins/*physiology ; Male ; Mice ; Mice, Inbred C57BL ; Motor Activity/radiation effects ; Naloxone/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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