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  • SPACE RADIATION  (432)
  • Life and Medical Sciences
  • 1980-1984  (463)
  • 1965-1969  (342)
  • 1955-1959  (37)
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Publisher
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 112 (1982), S. 10-18 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Intermediate subviral particles (ISVP) derived from reovirus represent a simple model system for the switch-on of transcriptase function. In such particles the endogenous transcriptase is present in a switched-off form, one step removed from the switched-on state. Switch-on of transcriptase function is an active process in this system and can be triggered by K+ ions. A variety of agents which affect gene expression in cells were tested for an effect on switch-on in ISVP. Marked effects on switch-on in ISVP were observed with a diverse group of test agents, including DMSO and other solvents, BUdR, TdR, caffeine, theophylline, and temperature. The correlation in response between ISVP and cells suggests that the ISVP system may be useful as a model for studying the biochemical mechanisms underlying the perturbative effects of such agents on gene expression in cells.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Gamete Research 4 (1981), S. 203-217 
    ISSN: 0148-7280
    Keywords: α-chlorohydrin ; antifertility agent ; ram ; sperm metabolism ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The effects of the male antifertility agent, α-chlorohydrin, six of its derivatives, and glycidol were studied on the metabolism of washed ram spermatozoa in vitro with fructose as substrate. The α-chlorohydrin derivatives were the amino, the phosphorylated, and four glycol-bridge (ketal) compounds. All compounds except glycidol, in a concentration between 0.1 and 100 mM, reduced the aerobic glycolsis and/or oxidation of fructose. However, there was not a high correlation between the ability of these compounds to inhibit the metabolism of ram spermatozoa in vitro and their antifertility activity when administered to male rats. Other factors are clearly involved in their antifertility activity, eg, the concentration of the compounds in the epididymis and their conversion of either more or less spermicidal compounds in the body.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0148-7280
    Keywords: spermatozoa ; flow cytometry ; DNA staining ; nuclear morphology ; ultrastructure ; mammals ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The morphological and ultrastructural changes that occur during preparation of porcine, bovine, and murine spermatozoa for flow cytometric quantification of the relative DNA content of the X- and Y-chromosome-bearing sperm populations were examined. Ejaculated spermatozoa from the boar and bull were washed using a series of dimethyl sulfoxide (DMSO) solutions prior to fixation, whereas the epididymal mouse spermatozoa were washed only in phosphate-buffered saline (PBS). Spermatozoa from all three species were then fixed in ethanol and processed for fluorochrome staining by a treatment regimen consisting of sulfhydryl reduction and proteolysis. The processed sperm nuclei were stained for DNA with the fluorochrome, 4′-6-diamidino-2-phenylindole (DAPI) before quantification by flow cytometry. Scanning and transmission electron micrographs of sperm heads taken at various steps of the preparation and staining procedures show 1) that the rigorous washing procedure disrupted the plasma and outer acrosomal membranes, 2) that ethanol fixation resulted in removal of the outer membranes and disintegration of the nuclear envelope, and 3) that thiol and proteolysis treatment removed the remaining cellular organelles including the tail and rapidly induced partial decondensation of the tightly packed chromatin. Sequential micrographs showed that the nuclear matrix of all three species increased in thickness about twofold during the preparation and staining. Consequently, the harsh procedures currently used for quantitative staining of DNA for high-resolution flow cytometric analyses destroy most cellular organelles and thereby prevent simultaneous characterization of DNA content and other sperm cell constituents.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2014-09-11
    Description: Very long base interferometry measurements of time delay and fringe frequency at 2.29 GHz on baselines of 10,000 km between Deep Space Network stations were used to determine the positions of the milliarcsecond nuclei in 207 extragalactic radio sources. Estimated accuracies generally range from approximately 0.1 to approximately 1.0, in both right ascension and declination, with all sources having uncertainties 4" in both coordinates. The observed sources are part of an all-sky VLBI catalog of milliarcsecond radio sources. Arcsecond positions are now determined for 752 of these sources. Arcsecond positions serve as a useful starting point in the construction of high-precision VLBI reference frames and are also important for unambiguous determination of optical counterparts to compact radio sources.
    Keywords: SPACE RADIATION
    Type: The Telecommun. and Data Acquisition Rept.; p 1-11
    Format: text
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  • 5
    Publication Date: 2011-08-18
    Description: Searches were made for pulsed high energy (E greater than 35 MeV) gamma radiation from 43 pulsars using the SAS-2 data base and radio parameters. No positive results were found, and the upper limits are consistent with the concept that gamma ray production efficiency increases with increasing apparent age. Two limits suggest that efficiency cannot be a simple function of apparent age beyond 1,000,000 years. Previously announced in STAR as N83-24463
    Keywords: SPACE RADIATION
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 127; 1, Oc
    Format: text
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  • 6
    Publication Date: 2011-08-12
    Description: Solar wind plasma observations in geomagnetospheric wake compared at 1000 and 500 earth radii, considering ion energy spectra and geomagnetic tail
    Keywords: SPACE RADIATION
    Type: ; ADEMIE DES SCIENCES
    Format: text
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  • 7
    Publication Date: 2014-09-12
    Description: A very long base interferometry (VLBI) survey at 2.29 GHz was conducted using a 275 km baseline consisting of the NASA Deep Space Network tracking site in Tidbinbilla, Australia, and the 64 m antenna located at Parkes, Australia. The purpose of the survey was to identify sources in the southern sky possessing strong compact cores ( 0.1 arcseconds). Such sources will be used to form a reference frame for conducting VLBI geodesy experiments in the Southern Hemisphere. The 70 candidate sources were chosen to be south of -39 degrees declination, and only four had been previously observed from the northern hemisphere. Of the observed sources, 49 were found to have compact structure. In addition to determining correlated flux densities, the delay and delay rate observables of several detected sources were used to determine an estimate of the three dimensional location of the Parkes antenna relative to the Tidbinbilla site with a 1-sigma accuracy of 10 meters.
    Keywords: SPACE RADIATION
    Type: The Telecommun. and Data Acquisition Rept.; p 183-187
    Format: text
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  • 8
    Publication Date: 2019-06-28
    Description: Searches were made for pulsed high energy (E 35 MeV) gamma radiation from 43 pulsars using the SAS-2 data base and radio parameters. No positive results were found, and the upper limits are consistent with the concept that gamma ray production efficiency increases with increasing apparent age. Two limits suggest that efficiency cannot be a simple function of apparent age beyond 10,000,000 years.
    Keywords: SPACE RADIATION
    Type: NASA-TM-84970 , NAS 1.15:84970
    Format: application/pdf
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 180 (1984), S. 29-35 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This study describes intercellular bridges in the ovaries of neonatal gerbils. Electron microscopy has revealed the presence of true intercellular bridges, connecting oogonia or oocytes, in ovaries of newborn gerbils. The cytoplasm of the intercellular channels is similar to that of the connected cells, with mitochondria, smooth and rough endoplasmic reticulum, and free ribosomes present. Lysosomes are also occasionally present in the intercellular bridges and they may be involved in early waves of oocyte atresia. An electrondense substance, 350-500 Å thick, is located immediately beneath the unit membrane of the intercellular bridges. Accumulation of electron-dense material increases the thickness of the walls of the intercellular bridges, supporting and maintaining the patency of the channels. It is suggested that the intercellular channels probably allow the interchange of nutrients, organelles, and possibly regulatory materials as well.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 180 (1984), S. 243-252 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A small short muscle frequently acts across a joint in parallel with a vastly larger and longer muscle; therefore it should play a minimal role in the mechanical control of that joint. This study provides evidence suggesting that the small member of such a “parallel muscle combination” (PMC) may serve an important sensory feedback role. The spindle densities of large and small members of PMCs in man and the dog were determined and compared. Epaxial PMCs controlling canine intervertebral joints were dissected and tissue samples were embedded in paraffin, sectioned transversely to the muscles' long axis and, stained with hematoxylin-periodic acid-Schiff (PAS). Representative tissue sections were projected on to stereological grids and the percentage volume of spindles was determined. Data existing in the literature were used to ascertain spindle densities in human PMCs controlling joints in the cervico-occipital region and the extremities. The spindle density for each muscle in a group of PMCs controlling a particular motion was listed, and the mean spindle densities were determined for both the large and the small members of the group. Student's unpaired t test was used to determine the significance of the differences between mean spindle densities. Linear regression was calculated and the data were plotted graphically.In all PMCs examined, the spindle density of the small muscles was significantly higher than that of their large counterparts. It is therefore proposed that the small muscles of PMCs may function as “kinesiological monitors” generating important proprioceptive feedback to the central nervous system.
    Additional Material: 3 Ill.
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