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  • 1980-1984  (3)
  • 1970-1974  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of engineering mathematics 5 (1971), S. 19-32 
    ISSN: 1573-2703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Technology
    Notes: Summary A solution is presented for the determination of thermal stresses in a finite cylinder heated axisymmetrically over the curved surface. The solution is obtained by constructing the thermoelastic displacement potential and the biharmonic Love function to satisfy all the boundary conditions. It considers the steady state stresses as well as the transient stresses.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 1981-04-01
    Description: Human marrow cells were processed sequentially by density centrifugation and by velocity sedimentation in serum-free Percoll gradients in order to purify megakaryocytes and to determine if these cells are the source of the growth factor derived from platelets. Cell homogenates were made from the resulting fractions and tested for growth-promoting activity(ies) in 3T3 cells and in well characterized human marrow fibroblasts. Growth was evaluated by 3H-TdR incorporation and changes in DNA cell content, as measured by flow microfluorometry. The highest mitogenic activity was derived from homogenates of low density (less than 1.050 g/cu cm), rapidly sedimenting cells. This fraction contained the highest percentage of megakaryocytes. The assessment of growth-promoting activity(ies) derived from various megakaryocyte-enriched marrow cell homogenates containing different proportions of megakaryocytes demonstrated a positive correlation between the number of megakaryocytes and their stimulatory capacity as determined by 3H-TdR uptake. The growth-promoting activities elicited from homogenates of platelets and marrow fractions enriched for megakaryocytes were similar. The dose--response curves for both were parallel, and they were both temperature resistant and trypsin sensitive. These findings implicate megakaryocytes as a source of the growth factor derived from platelets and suggest that megakaryocytes may play a role in the pathogenesis of the marrow fibrosis observed in myeloproliferative disorders by stimulating fibroblast proliferation and collagen secretion.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 3
    Publication Date: 1981-04-01
    Description: Human marrow cells were processed sequentially by density centrifugation and by velocity sedimentation in serum-free Percoll gradients in order to purify megakaryocytes and to determine if these cells are the source of the growth factor derived from platelets. Cell homogenates were made from the resulting fractions and tested for growth-promoting activity(ies) in 3T3 cells and in well characterized human marrow fibroblasts. Growth was evaluated by 3H-TdR incorporation and changes in DNA cell content, as measured by flow microfluorometry. The highest mitogenic activity was derived from homogenates of low density (less than 1.050 g/cu cm), rapidly sedimenting cells. This fraction contained the highest percentage of megakaryocytes. The assessment of growth-promoting activity(ies) derived from various megakaryocyte-enriched marrow cell homogenates containing different proportions of megakaryocytes demonstrated a positive correlation between the number of megakaryocytes and their stimulatory capacity as determined by 3H-TdR uptake. The growth-promoting activities elicited from homogenates of platelets and marrow fractions enriched for megakaryocytes were similar. The dose--response curves for both were parallel, and they were both temperature resistant and trypsin sensitive. These findings implicate megakaryocytes as a source of the growth factor derived from platelets and suggest that megakaryocytes may play a role in the pathogenesis of the marrow fibrosis observed in myeloproliferative disorders by stimulating fibroblast proliferation and collagen secretion.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 4
    Publication Date: 2019-07-13
    Description: A continuous-vorticity panel method is developed and utilized to predict the steady aerodynamic loads on lifting surfaces having sharp-edge separation. Triangular panels with linearly varying vorticity are used. The velocity field generated by an individual element is obtained in closed form. An optimization scheme is constructed for finding the vorticity at the nodes of the elements. The method is not restricted by aspect ratios, angles of attack, planforms, or camber. Rectangular and delta wings are presented as numerical examples. The numerical results are in good agreement with the experimental data for incompressible flows.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 81-1895 , Atmospheric Flight Mechanics Conference; Aug 19, 1981 - Aug 21, 1981; Albuquerque, NM
    Format: text
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