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  • Articles  (343)
  • Wiley-Blackwell  (343)
  • American Chemical Society
  • 1980-1984  (186)
  • 1975-1979  (157)
  • Technology  (343)
  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 17 (1983), S. 59-70 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Porous high-density polyethylene specimens were implanted in the femurs of mongrel canines. At the end of the residency period (3 or 6 months), the animals were sacrificed and the implants were retrieved. The work-of-fracture of the implant specimens was then determined using the technique of Tattersall and Tappin. The work required to fracture a specimen in three-point bending by controlled crack propagation through a triangular cross section was obtained directly from the load-deflection curve. The area of the resulting fracture surface was measured by macro-photographic techniques, and the work-of-fracture was calculated as work per unit area. The implants were subsequently sectioned and examined microradiographically to determine the extent of bone ingrowth. Bone specimens adjacent to the implants and porous high-density polyethylene controls (no ingrowth) were also tested to determine their work-of-fracture. The results showed that bone adjacent to the implant specimens had a higher work-of-fracture than normal medial, canine femoral bone and was not appreciably different from the composite. The work-of-fracture of porous high-density polyethylene was not significantly increased by an increase in bone infiltration, and this anomalous behavior was attributed to a degradation of the polyethylene during implant residence. Control studies supported this hypothesis.
    Additional Material: 7 Ill.
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 11 (1977), S. 489-502 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Physical and in vivo (burned rat model) evaluations as wound coverings were performed for 1) a freeze-dried collagen/poly (∊-caprolactone) (PCL) film laminate, 2) a freeze-dried PCL “foam”/PCL film laminate, and 3) a heat-dried collagen/PCL film laminate. Porcine skin and cadaver skin were also evalulated in vivo for the purpose of comparison. Water-vapor transmission rates and Young's moduli were measured. The degrees of adherence of the coverings to the wound were measured. Grafts which became significantly adherent (〉150 dyne/cm2) to the wound within 1 day were most successful in promoting the formation of a viable tissue bed which appeared ready to accept further grafting. The force required to remove the PCL foam laminate from a full-thickness excision wound was found to increase from 170 dyne/cm2 on the first day postgraft to 1500 dyne/cm2 by the tenth day. The force required to remove freeze-dried collagen laminate remained constant at 200 dyne/cm2 over the 10 day test period. For the heat-dried collagen laminate, a force of only 50 dyne/cm2 was required on day 1, increasing to 200 dyne/cm2 on day 6. Insensible water-loss rates of animals grafted with the laminates were found to be similar to those from animals with human cadaver skin grafts and less than that from animals with porcine skin grafts. When moistened, the laminates prepared using the freeze-dried materials were flexible and somewhat transparent permitting observation of the wound.
    Additional Material: 4 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 13 (1979), S. 765-782 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Kinetic and equilibrium studies of blood platelet binding to copolypeptide films show that attachment and serotonin release are not dependent upon the composition of the copolypeptide. Data may be explained by postulating that platelets frequently collide elastically with the surface but leave behind material that modifies subsequent behavior. Similarly, material released from platelets adsorbs at the interface and the extent of attachment and serotonin release are modified and controlled by these adsorbed species. Basically, if the platelet is exposed to a clean surface, its collision with the surface leads to activation and release. In the presence of inert protein, the collision is cushioned by the protein and platelets do not attach or release to any extent. Finally, if protein (or other entities) released from the platelet provide attachment sites, than attachment occurs without release. It is postulated that the behavior of platelets at surfaces is controlled by these interrelated processes.
    Additional Material: 6 Ill.
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 16 (1982), S. 381-398 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Numerous hypotheses exist to explain observed blood-materials interactions. It is the purpose of this article to test two popular hypotheses, namely, the minimum interfacial free energy hypothesis and the optimum polar/apolar ratio hypothesis. Methacrylate polymers and copolymers were characterized using the captive bubble underwater contact angle method; bulk water content was determined by gravimetric methods; streaming potential measurements were made; and surface roughness and possible particulate contamination were evaluated by reflected light microscopy. In vitro blood tests include whole blood clotting time measurements on polymer-coated tubes; centrifugal force platelet adhesion on polymer-coated coverslips; and a measure of the partial thromboplastin time, Russell's viper venom time (Stypven time), and the prothrombin time of native whole blood exposed to polymer-coated microscope slides. Results suggest that platelet adhesion correlates in the opposite direction of whole blood clotting time and partial thromboplastin time, emphasizing the need for a multiparameter approach to blood-materials testing. Based on these tests the minimum interfacial free energy hypothesis is not supported. In fact, the data suggest the opposite to be true. It is apparent that platelet adhesion can be a misleading indicator of blood compatibility. Neither hypotheses can explain the apparent conflict between the platelet adhesion data and the coagulation time data.
    Additional Material: 9 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 14 (1979), S. 531-544 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A high precision triangular thick orthotropic plate bending element on an elastic foundation is developed for the free vibration analysis of thick plates on elastic foundation. The element has three nodes with twelve degrees-of-freedom per node, and takes into account the shear deformation and rotatory inertia. The accuracy of the element is established by comparison of the natural frequencies of certain thick and thin plates, determined from a consistent mass matrix formulation, with available results.
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  • 6
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 18 (1982), S. 1505-1520 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The present paper deals with the theoretical and numerical treatment of dynamic unilateral problems. The governing equations are formulated as an equivalent variational inequality expressing D' Alembert's principle in its inequality form. The discretization with respect to time and space leads to a static nonlinear programming problem which is solved by an appropriate algorithm. Some properties of dynamic unilateral problems are outlined and the influence of several parameters on the solution is investigated by means of numerical examples.
    Additional Material: 9 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 20 (1984), S. 1067-1084 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A linear model for the solidification of a dilute binary alloy is presented. In this model the solidus and liquidus curves are linear. As a consequence internal energy depends linearly upon temperature and concentration. The formulation is a generalization of the well-known enthalpy method to treat a phase change problem involving coupled heat and mass transfer. Both analytic and numerical formulations are given. Results from the latter are presented and compared with an explicit solution of Rubinstein for a Stefan-like problem posed in a semi-infinite slab. Some remarks on the behaviour of the explicit solution are given.
    Additional Material: 5 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 11 (1977), S. 1049-1052 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Additional Material: 1 Ill.
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  • 9
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 597-612 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A general-purpose technique has been developed for solving non-linear partial differential equations. A set of approximating functions with undetermined parameters is used to evaluate the differential equation and boundary conditions at discrete points, forming a set of residuals to be minimized. The parameters which minimize the sum of squared residuals are determined by a non-linear least-squares minimization technique. Initial value problems are solved by integrating the equations with respect to time at the fitting points by a predictor-corrector algorithm. The resulting formulation is independent of the form of the problem and the approximating functions, so that a broad class of problems may be solved with a single computer program. The technique is applied to several boundary and initial value problems in one and two spatial dimensions. The tecnique is applied to several boundary and initial value problems in one and two spatial dimensions.
    Additional Material: 5 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 20 (1984), S. 1169-1174 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Additional Material: 2 Tab.
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