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  • COMPOSITE MATERIALS  (6)
  • Animals  (5)
  • ASTRODYNAMICS  (3)
  • 1980-1984  (8)
  • 1975-1979  (6)
  • 1970-1974
  • 1
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    Fractional factorial analysis of growth and weaning success in Peromyscus maniculatus (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-24
    Description: Fractional factorial designs were used to explore simultaneously the effects of eight variables on survival and growth of neonatal deer mice, Peromyscus maniculatus. Two of the variables had significant effects on weaning success. The magnitudes of their effects are illustrated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Porter, W P -- Busch, R L -- New York, N.Y. -- Science. 1978 Nov 24;202(4370):907-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715451" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn/physiology ; Animals, Suckling/physiology ; Body Temperature Regulation ; Body Weight ; Food Deprivation ; Maternal Behavior ; Peromyscus/*physiology ; Water Deprivation ; Weaning
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Plasticity of motor behavior in monkeys with crossed forelimb nerves (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-04-22
    Description: Monkeys in which nerves innervating the flexor muscles of the forearm and hand (the ulnar or the median nerve) had been surgically cross-united with the nerve innervating the extensor muscles (the radial nerve), and vice versa, showed excellent (ulnar-radial crosses) to moderate (median-radial crosses) control of movement performance after regeneration. Antagonistic movement responses were seen occasionally, but these were corrected almost immediately. Stimulation of the crossed nerves showed that they had innervated the antagonistic muscle groups. The results reveal the capacity of the primate central nervous system to adapt to gross disturbances imposed on the execution of movements by changes in peripheral innervation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brinkman, C -- Porter, R -- Norman, J -- New York, N.Y. -- Science. 1983 Apr 22;220(4595):438-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836289" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Fingers/physiology ; Forearm/*innervation/physiology ; Hand/innervation/physiology ; Humans ; Macaca fascicularis ; Macaca nemestrina ; Median Nerve/physiology ; *Movement ; *Neuronal Plasticity ; Radial Nerve/physiology ; Thumb/physiology ; Ulnar Nerve/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Corollary discharge provides accurate eye position information to the oculomotor system (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-16
    Description: The saccadic system accurately compensates for perturbations of eye position produced by microstimulation of the superior colliculus. This requires that information about the stimulation-induced change in eye position be provided by an extraretinal source--either proprioceptive endings in extraocular muscles or a centrally generated corollary discharge. It is shown that compensation remains intact after elimination of extraocular muscle proprioception, demonstrating that corollary discharge provides accurate eye position information.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Guthrie, B L -- Porter, J D -- Sparks, D L -- F32 EY05651/EY/NEI NIH HHS/ -- P30 EY03039/EY/NEI NIH HHS/ -- R01 EY01189/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 16;221(4616):1193-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6612334" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Eye Movements ; Macaca mulatta ; Oculomotor Muscles/*physiology ; Photic Stimulation ; Proprioception ; *Saccades ; Superior Colliculi/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Spermidine requirement for cell proliferation in eukaryotic cells: structural specificity and quantitation (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-03-04
    Description: Six structural homologs of spermidine and five of its precursor, putrescine, were studied for their ability to prevent cytostasis of cultured L1210 leukemia cells induced by alpha-difluoromethylornithine (DFMO), a specific inhibitor of putrescine biosynthesis. High-performance liquid chromatography and competition studies with spermidine indicated that the homologs, which vary in the length of the carbon chain separating the amines, penetrated the cells. The structural specificity of the spermidine carrier was defined. Three of the six spermidine homologs supported cell growth during a 48-hour incubation in the presence of DFMO, indicating that a two-carbon extension of spermidine structure was tolerated for biological function. Two of the five putrescine homologs supported growth after being converted by the cells to their respective spermidine homologs. The central nitrogen of spermidine appears to be essential for function since diamines of chain length comparable to that of spermidine did not prevent DFMO cytostasis. No more than 15 percent of the spermidine normally present in L1210 cells was required for cell proliferation in the presence of DFMO.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Porter, C W -- Bergeron, R J -- CA-22153/CA/NCI NIH HHS/ -- CA-24538/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1983 Mar 4;219(4588):1083-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6823570" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Division ; *Cell Physiological Phenomena ; Eukaryotic Cells/*physiology ; Leukemia L1210/pathology ; Mice ; Ornithine Decarboxylase Inhibitors ; Putrescine/physiology ; Spermidine/analogs & derivatives/*physiology ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Toxicant-disease-environment interactions associated with suppression of immune system, growth, and reproduction (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-01
    Description: The effects of marginal malnourishment , infections, and environmental chemicals on growth and reproductive success in Swiss-Webster white mice and wild deer mice were studied with fractional factorial designs. Interaction effects were discovered. For example, malnourished mice were more sensitive to virus exposure and environmental chemicals (a plant growth regulator or polychlorinated biphenyls). Since several commercial plant growth regulators also appear to suppress the immune system, these results cast doubt on the adequacy of current toxicity testing procedures in which factors are studied individually and not in combination.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Porter, W P -- Hinsdill, R -- Fairbrother, A -- Olson, L J -- Jaeger, J -- Yuill, T -- Bisgaard, S -- Hunter, W G -- Nolan, K -- 5-T32-ES07015/ES/NIEHS NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 1;224(4652):1014-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6426058" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Wild ; Chlormequat/adverse effects ; Cyclophosphamide/adverse effects ; Encephalomyelitis, Venezuelan Equine/physiopathology ; Environmental Exposure ; Female ; Food Supply ; Growth/*drug effects ; Humans ; Immunity/*drug effects ; Mice ; Nutrition Disorders/physiopathology ; Peromyscus ; Polychlorinated Biphenyls/adverse effects ; Pregnancy ; Reproduction/*drug effects ; Water Supply
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Estimation of Kalman filter model parameters from an ensemble of tests (1980)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: A methodology for estimating initial mean and covariance parameters in a Kalman filter model from an ensemble of nonidentical tests is presented. In addition, the problem of estimating time constants and process noise levels is addressed. Practical problems such as developing and validating inertial instrument error models from laboratory test data or developing error models of individual phases of a test are generally considered.
    Keywords: ASTRODYNAMICS
    Type: NASA. Goddard Space Flight Center Fifth Ann. Flight Mech.(Estimation Theory Symp.; 29 p
    Format: application/pdf
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  • 7
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    Multiple object tracking with non-unique data-to-object association via generalized hypothesis testing (1979)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: A generalized hypothesis testing approach is applied to the problem of tracking several objects where several different associations of data with objects are possible. Such problems occur, for instance, when attempting to distinctly track several aircraft maneuvering near each other or when tracking ships at sea. Conceptually, the problem is solved by first, associating data with objects in a statistically reasonable fashion and then, tracking with a bank of Kalman filters. The objects are assumed to have motion characterized by a fixed but unknown deterministic portion plus a random process portion modeled by a shaping filter. For example, the object might be assumed to have a mean straight line path about which it maneuvers in a random manner. Several hypothesized associations of data with objects are possible because of ambiguity as to which object the data comes from, false alarm/detection errors, and possible uncertainty in the number of objects being tracked. The statistical likelihood function is computed for each possible hypothesized association of data with objects. Then the generalized likelihood is computed by maximizing the likelihood over parameters that define the deterministic motion of the object.
    Keywords: ASTRODYNAMICS
    Type: NASA. Goddard Space Flight Center Flight Mech.(Estimation Theory Symp.; p 169-182
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  • 8
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    Environmental effects on defect growth in composite materials (1981)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: Data for evaluating the effects of moisture and temperature on the integrity of fiber composite components was gathered. In particular, the static and cyclic performance of three composite laminates containing flaws was investigated at room temperature and at 422 K (300 F) in wet and dry conditions.
    Keywords: COMPOSITE MATERIALS
    Type: NASA-CR-165213 , NAS 1.26:165213
    Format: application/pdf
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  • 9
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    Circular earth orbits attainable with fixed two-impulse expendable tug (1975)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: The performance of solid rocket motors in expendable stages as an alternative concept for Shuttle interim upper stage applications is assessed from the standpoint of mission flexibility. The system comprises two stages and a payload, released from a circular Shuttle orbit at 160 naut miles altitude. The stages are sized to deliver a given payload mass to synchronous equatorial orbit. Only nonreturn missions are considered. A parametric sweep was made with small increments of pitch and yaw to compute the possible transfer orbits with an apogee greater than 160 naut miles. At several points on each transfer orbit the possibility of attaining a circular orbit with the second burn impulse of 6000 fps was assessed. Constraints on the vertical component of the second impulse and on the total velocity after firing determine the pitch angle for second burn. Results indicate a fixed two-impulse system designed to place a payload into synchronous equatorial orbit from the Shuttle orbit can deliver the payload mass into any lower circular orbit at any inclination within about 30 deg of the Shuttle orbit. The only apparent disadvantage of the system is an inability to achieve circular orbits above geosynchronous altitudes with the design payload.
    Keywords: ASTRODYNAMICS
    Type: Journal of Spacecraft and Rockets; 12; Oct. 197
    Format: text
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  • 10
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    Effect of preload on the fatigue and static strength of composite laminates with defects (1977)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: The effect of a preload cycle on the structural performance of three graphite/epoxy composite laminates was studied. The layups studied were a laminate typical of general purpose structures (L1), a laminate representative of a filament wound tank (L2), and a laminate representative of turboengine fan blades. The effects of three sizes of simulated initial defects were studied. The tests developed static strength data, fatigue to failure data, and residual static data after application of a predetermined number of fatigue cycles. For L1 specimens, there was a slight trend for the static strength to be greater for preloaded specimens. After application of cyclic loading, however, the influence of preloading was insignificant. In L2 and L3 specimens there was no consistent difference in the static or fatigue results between preloaded and nonpreloaded specimens.
    Keywords: COMPOSITE MATERIALS
    Type: Annual Meeting on Recent advances in engineering science; Nov 14, 1977 - Nov 16, 1977; Bethlehem, PA
    Format: text
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