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  • LUNAR AND PLANETARY EXPLORATION  (10)
  • Humans  (4)
  • OCEANOGRAPHY  (2)
  • 1985-1989  (10)
  • 1975-1979  (6)
  • 1
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    Molecular defects in insulin action (1989)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1989-07-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kahn, C R -- Goldstein, B J -- New York, N.Y. -- Science. 1989 Jul 7;245(4913):13.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2662406" target="_blank"〉PubMed〈/a〉
    Keywords: Diabetes Mellitus/*physiopathology ; Humans ; Insulin/*physiology ; Insulin Resistance
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Contact-mediated bone resorption by human monocytes in vitro (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-03
    Description: Human circulating monocytes in tissue culture are capable of resorbing devitalized adult and fetal bone. An important component of this process is the adhesion of the cells to the mineralized substrate and the localized removal of matrix from beneath the attached cells. The process appears to involve both release of lysosomal enzymes onto the substrate and intracellular accumulation (transport) of resorbed matrix.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kahn, A J -- Stewart, C C -- Teitelbaum, S L -- New York, N.Y. -- Science. 1978 Mar 3;199(4332):988-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/622581" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bone Matrix/cytology/metabolism/physiology ; *Bone Resorption ; Bone and Bones/embryology/metabolism ; Calcium Radioisotopes ; Cell Adhesion ; Culture Techniques ; Humans ; Monocytes/cytology/metabolism/*physiology ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Radioimmunoassay of the insulin receptor: a new probe of receptor structure and function (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: A sensitive and specific radioimmunoassay for the insulin receptor has been developed employing receptor autoantibodies from the serum of a patient with insulin-resistant diabetes. The assay detects insulin binding sites at concentrations as low as 0.1 nanomolar; distinguishes between receptors originating from human placental membranes, human lymphoblastoid cells, and mouse liver membranes; and measures the receptor independently of its binding function. Down-regulation, or loss of binding after exposure to insulin, is associated with loss of immunoreactive receptor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harrison, L C -- Flier, J -- Itin, A -- Kahn, C R -- Roth, J -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):544-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/83675" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Antibody Reactions ; Binding Sites ; Binding Sites, Antibody ; Epitopes ; Female ; Humans ; Liver/analysis ; Lymphocytes/analysis ; Mice ; Placenta/analysis ; Pregnancy ; Radioimmunoassay/methods ; Receptor, Insulin/analysis/*immunology ; Solubility
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Human aging: usual and successful (1987)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1987-07-10
    Description: Research in aging has emphasized average age-related losses and neglected the substantial heterogeneity of older persons. The effects of the aging process itself have been exaggerated, and the modifying effects of diet, exercise, personal habits, and psychosocial factors underestimated. Within the category of normal aging, a distinction can be made between usual aging, in which extrinsic factors heighten the effects of aging alone, and successful aging, in which extrinsic factors play a neutral or positive role. Research on the risks associated with usual aging and strategies to modify them should help elucidate how a transition from usual to successful aging can be facilitated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rowe, J W -- Kahn, R L -- New York, N.Y. -- Science. 1987 Jul 10;237(4811):143-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3299702" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Aged, 80 and over ; *Aging/metabolism/physiology/psychology ; Carbohydrate Metabolism ; Cognition ; Cross-Sectional Studies ; Grief ; Health Promotion ; Health Services for the Aged ; Humans ; Longitudinal Studies ; Osteoporosis/physiopathology ; Patient Acceptance of Health Care ; Reference Values ; Social Support ; Volition
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    The Evolution of CO2 on Mars (1985)
    In:  CASI
    Details
    Publication Date: 2014-10-08
    Description: The consequences of the hypothesis that the evolution of CO2 is directly linked to the occurrence of at least transitory pockets of moisture were exposed. The current conditions preclude the existence of open bodies of liquid water and the formation of moisture in disequilibrium is not excluded by any known constraints. The water evaporation rate is inversely proportional to PCO2, and the existence of a limiting value (P*) for which liquid water can form in the Mars environment is postulated. The evolution of PCO2 is controlled largely by relatively rapid aqueous chemistry forming carbon-containing sedimentary rocks, perhaps during early history in open water, but more recently in transitory pockets of moisture in the soil. Once the total atmospheric pressure is reduced to near P*, the occurrence of transitory moisture is inhibited, and atmospheric CO2 is no longer depleted by an efficient mechanism. The role of the carbonate reservoir in the current overall carbon budget on Mars, according to this scheme, is illustrated.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA, Washington Repts. of Planetary Geol. and Geophys. Program; p 232-234
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  • 6
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    Ocean gravity and geoid determination (1979)
    In:  Other Sources
    Details
    Publication Date: 2011-08-17
    Description: Gravity anomalies have been recovered in the North Atlantic and the Indian Ocean regions. Comparisons of 63 2 deg x 2 deg mean free air gravity anomalies recovered in the North Atlantic area and 24 5 deg x 5 deg mean free air gravity anomalies in the Indian Ocean area with surface gravimetric measurements have shown agreement to + or - 8 mGal for both solutions. Geoids derived from the altimeter solutions are consistent with altimetric sea surface height data to within the precision of the data, about + or - 2 m.
    Keywords: OCEANOGRAPHY
    Type: Journal of Geophysical Research; 84; July 30
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  • 7
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    Cratering and obliteration history of the south polar region of Mars (1987)
    In:  CASI
    Details
    Publication Date: 2013-08-31
    Description: Results are presented from a comprehensive analysis of crater size frequency distributions compiled from Viking Orbiter images of Martian south polar terrains. Depositional histories for the various terrain units are modelled based on deviations of cumulative crater size frequency plots from an assumed production function. Stratigraphic and morphologic data obtained from visual examination of Viking images are also used, primarily to corroborate inferences concerning ages and obliteration histories derived from the crater data.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA, Washington, Reports of Planetary Geology and Geophysics Program, 1986; p 418-419
    Format: application/pdf
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  • 8
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    Mean sea level determination from satellite altimetry (1979)
    In:  Other Sources
    Details
    Publication Date: 2011-08-17
    Description: The primary experiment on the Geodynamics Experimental Ocean Satellite-3 (GEOS-3) is the radar altimeter. This experiment's major objective is to demonstrate the utility of measuring the geometry of the ocean surface; i.e., the geoid. Results obtained from this experiment so far indicate that the planned objectives of measuring the topography of the ocean surface with an absolute accuracy of + or - 5 m can be met and perhaps exceeded. The GEOS-3 satellite altimeter measurements have an instrument precision in the range of + or - 25 cm to + or - 50 cm when the altimeter is operating in the 'short pulse' mode. After one year's operations of the altimeter, data from over 5000 altimeter passes have been collected. With the mathematical models developed and the altimeter data presently available, mapping of local areas of ocean topography has been realized to the planned accuracy levels and better. This paper presents the basic data processing methods employed and some interesting results achieved with the early data. Plots of mean sea surface heights as inferred by the altimeter measurements are compared with a detailed 1 by 1 deg gravimetric geoid.
    Keywords: OCEANOGRAPHY
    Type: Marine Geodesy; 2; 2, 19; 1979
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  • 9
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    Deducing the age of the dense Venus atmosphere (1989)
    In:  Other Sources
    Details
    Publication Date: 2019-01-25
    Description: It is shown how crater size-density counts may be used to help constrain the history of the Venus atmosphere, based on the predictions of simple but reasonable models for crater production, surface erosion, and the effects of atmospheric drag and breakup on incident meteors in the Venus atmosphere. In particular, if the atmosphere is young, the old (uneroded) surfaces will have crater densities upward of 0.0001/sq km and a ratio of small (4 km) craters to large (128 km) craters near 1000. If the atmosphere is old and the breakup mechanism is dominant, absolute crater densities on Venus surfaces will be diminished by several orders of magnitude relative to the young atmosphere case. If atmospheric drag is dominant, the absolute crater density will be lowered by perhaps an order of magnitude relative to the young atmosphere case, and the ratio of small to large craters will be reduced to a value near 10 to the 1.5 power. Once a large fraction of Venus surface has been imaged at kilometer resolution, as the Venus Orbiting Imaging Radar project promises to do, it could be possible to make an early determination of the age of the Venus atmosphere.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Lunar and Planetary Inst., Abstracts for the Venus Geoscience Tutorial and Venus Geologic Mapping Workshop; p 26
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  • 10
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    The evolution of CO2 on Mars (1985)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: At the surface, the atmosphere of Mars contains approximately 95.3 percent CO2 by volume. At the Viking Lander 1 (VL1) site, the total surface pressure varied with the season between about 6.89 and 8.94 mbar. Questions related to the observed CO2 pressure on Mars are explored. Several published estimates of the total amount of CO2 outgassed over the history of Mars, varying between 140 and 3000 mbar, are shown in a table. It is pointed out that the study of likely reservoirs for outgassed CO2 has focused mainly on the polar caps and regolith. Constraints on the formation of transitory pockets of moist soil are discussed, taking into account heat requirements, supply of water, and constraints related to pressure. Attention is also given to chemical considerations, implications for the current status of CO2 reservoirs, and scenarios for the evolution of CO2 pressure.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Icarus (ISSN 0019-1035); 62; 175-190
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