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  • 1
    Publication Date: 2022-06-13
    Description: The determination of the natural remanent magnetization (NRM) of archaeological features can be used for magnetic modelling, joining of shards, archaeomagnetic dating or the investigation of the firing–cooling–collapsing order of ancient buildings. The measurement of NRM is normally conducted on cylindrical or cubic samples in the laboratory. Nevertheless, archaeological finds should preferably not be destroyed, and laboratory instruments are high in costs. Therefore, we propose a lightweight and portable measurement set-up including already available field magnetometers (preferably caesium magnetometers) in which the archaeological sample of arbitrary shape, in our case a piece of daub, is mounted inside a gimbal to be rotated in all directions. The magnetic field of the sample is measured at a large number of rotational positions with the magnetometer kept at fixed position. In these measurements, the unknown direction of the NRM vector of the sample is rotated, whereas the average magnetic susceptibility of the sample and the ambient magnetic field are constant and known. Hence, the vector of NRM can be determined through least-squares inversion. For the inversion computation, the sample volume is discretized either as voxel model or approximated as an equivalent sphere. Under certain conditions depending on sample–sensor distance, dipole moment and radius of the sample, the approximation by a sphere is valid without effect on the accuracy of results. Empirically determined functions quantifying these conditions for different sensor sensitivities and noise levels are provided. Validation with laboratory measurements on palaeomagnetic subsamples from the destroyed daub samples indicate that the NRM can be determined by our proposed method with a maximum error in inclination of 2°, in declination of 20° and in magnetization of ±0.6 A/m. This is accurate enough, for example, to determine from daub pieces of burnt house remains whether the building was burnt and cooled before or after it collapsed.
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 2
    Publication Date: 2017-04-04
    Description: In the last twelve years, Mt. Etna, located in eastern Sicily, has produced a great number of explosive eruptions. Volcanic plumes have risen to several km above sea level and created problems for aviation and the communities living near the volcano. A reduction of hazards may be accomplished using remote sensing techniques to evaluate important features of volcanic plumes. Since 2000, the Multiangle Imaging SpectroRadiometer (MISR) on board NASA’s Terra spacecraft has been extensively used to study aerosol dispersal and to extract the three-dimensional structure of plumes coming from anthropogenic or natural sources, including volcanoes. In the present work, MISR data from several explosive events occurring at Etna are analyzed using a program named MINX (MISR INteractive eXplorer). MINX uses stereo matching techniques to evaluate the height of the volcanic aerosol with a precision of a few hundred meters, and extracts aerosol properties from the MISR Standard products. We analyzed twenty volcanic plumes produced during the 2000, 2001, 2002–03, 2006 and 2008 Etna eruptions, finding that volcanic aerosol dispersal and column height obtained by this analysis is in good agreement with ground-based observations. MISR aerosol type retrievals: (1) clearly distinguish volcanic plumes that are sulphate and/or water vapor dominated from ash-dominated ones; (2) detect even low concentrations of volcanic ash in the atmosphere; (3) demonstrate that sulphate and/or water vapor dominated plumes consist of smaller-sized particles compared to ash plumes. This work highlights the potential of MISR to detect important volcanic plume characteristics that can be used to constrain the eruption source parameters in volcanic ash dispersion models. Further, the possibility of discriminating sulphate and/or water vapor dominated plumes from ash-dominated ones is important to better understand the atmospheric impact of these plumes
    Description: Published
    Description: D06210
    Description: 1.5. TTC - Sorveglianza dell'attività eruttiva dei vulcani
    Description: JCR Journal
    Description: restricted
    Keywords: volcanic ash plume ; MISR ; 01. Atmosphere::01.01. Atmosphere::01.01.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 19 (1981), S. 11-18 
    ISSN: 1432-1041
    Keywords: disopyramide ; cardiac arrhythmias ; lidocaine ; torsade de pointe ; efficacy ; side effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The efficacy of intravenous disopyramide was studied during 200 episodes of supraventricular and ventricular arrhythmias in 160 patients, mainly presenting with acute myocardial infarction or cardiac failure. Disopyramide 50 mg was administered in a few seconds and any remaining dose within 2 to 5 min. The overall success rate was 80.5%. Intravenous disopyramide was more effective in patients with ventricular arrhythmias (85%) than in those with supraventricular arrhythmias (76%). Dose dependent prolongation of the PR interval, QRS time and the QT interval occurred in 16.32 and 20% of the cases, respectively. The adverse effects were aggravation of the arrhythmias, decrease of blood pressure and anticholinergic activity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 91 (1989), S. 5097-5102 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The diffusion of hydrogen in NaA zeolite was studied by incoherent neutron scattering. An experiment was carried out on samples loaded with 1.2 to 3.4 molecules per cavity and at several temperatures from 70 to 150 K. The angular (θ) dependence of the elastic and quasielastic intensities shows that the H2 molecule has a translational motion in a nonrestricted volume. A diffusion model where the molecule undergoes isotropic jumps of mean length l¯=3.9 A(ring) independent of temperature and is at rest for a time τ0 between two jumps accounts for the width of the quasielastic scattering in the entire (θ,T) range (τ0=10.8 ps at T=100 K). This leads to a diffusion coefficient D(cm2/s)=6×10−4 exp(E/RT) with E=2 kJ/mol for the less loaded samples. The diffusion coefficient increases slightly with the loading.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 90 (1989), S. 7482-7491 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A molecular dynamical study of one methane molecule in a cavity of NaA zeolite is performed in order to compare calculated to experimental data obtained by infrared spectroscopy and neutron scattering experiments in the temperature range 300–30 K. The calculation shows the trajectory of the molecule in the cavity and then the occupied volume as a function of energy. It allows the calculation of average quantities and correlation functions: (i) the mean field felt by the molecule comparable to the field responsible for the induced infrared band ν1, (ii) the average of the potential energy (to be compared to the heat of adsorption) and of the velocity squared, (iii) the external frequency distribution, and (iv) the position autocorrelation function which is related to the dynamical structure factor seen by neutron scattering.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 55 (1999), S. 157-167 
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: A previous article [Fourme et al. (1995). J. Synchrotron Rad. 2, 36–48] presented the theoretical foundations of MASC, a new contrast-variation method using multiwavelength anomalous scattering, and reported the first experimental results. New experiments have been conducted both at the ESRF (Grenoble, France) and at LURE-DCI (Orsay, France), using cryocooled crystals of three proteins of known structures and very different molecular weights. Amplitudes of \{\Gamma_T({\bf h})\}, the `normal' structure factors of the anomalously scattering part of the crystal including the solvent zone and the ordered anomalous scattering sites (if any), have been extracted from multiwavelength data. In the very low resolution range (d \ge 20 Å), the agreement between experimental \{|\Gamma_T({\bf h})|\} and model values calculated from the bulk solvent is all the more satisfactory since the molecular weight of the protein is high. For spacings between 10 and 20 Å, the agreement between experimental \{|\Gamma_T({\bf h})|\} and model values is also satisfactory if one takes into account ordered anomalous scatterer sites. Such sites have been found in the three cases.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 56 (2000), S. 1288-1303 
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The basic theory and principles of the multiple-wavelength anomalous solvent-contrast (MASC) method are introduced as a contrast-variation technique for generating low-resolution crystallographic phase information on the envelope of a macromolecule. Experimental techniques and practical considerations concerning the choice of anomalous scatterer, sample preparation and data acquisition are discussed. Test cases of crystals of three proteins of differing molecular weights from 14 kDa through to 173 kDa are illustrated. Methods for extracting the moduli of the anomalous structure factors from the MASC data are briefly discussed and the experimental results are compared with the known macromolecular envelopes. In all cases, the lowest resolution shells exhibit very large anomalous signals which diminish at higher resolution, as expected by theory. However, in each case the anomalous signal persists at high resolution, which is strong evidence for ordered sites of the anomalous scatterers. For the smaller two of these proteins the heavy-atom parameters could be refined for some of these sites. Finally, a novel method for phasing the envelope structure-factor moduli is presented. This method takes into account the relatively low number of observations at low resolution and describes the macromolecular envelope with a small number of parameters by presuming that the envelope is a compact domain of known volume. The parameterized envelope is expressed as a linear combination of independent functions such as spherical harmonics. Phasing starts from solutions of a sphere in the unit cell after positional refinement from random trials and the parameters describing the envelope are then refined against the data of structure-factor moduli. The preliminary results using simulated data show that the method can be used to reconstruct the correct macromolecular envelope and is able to discriminate against some false solutions.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 768-777 
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: We report the cDNA sequence determination and the crystal structure of the Fab fragment of a murine IgG1,λ antibody (HC19), specific for an influenza virus hemagglutinin. The HC19 Fab-fragment structure has been refined; the crystallographic R-factor is 19.5% at 2.3 Å resolution. We have compared the conformation of HC19 complementarity determining regions (CDRs) with those of CDR loops of Fab structures available from the Protein Data Bank. These loops were chosen based on the identity of key residues, following the canonical-structure approach; four CDRs have a main-chain conformation very similar to the canonical structure that had been identified. HC19 L1 CDR adopts a conformation clearly distinct from all L1 CDRs that belong to a chain of a different class or origin; this is determined by the nature of a few residues at positions in the sequence different from those of key residues in other light chains. This canonical structure should be representative of most murine λ-class light chains, as inferred from the very high sequence homologies of these polypeptides.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: A probability distribution of the structure factor is established from the analysis of the effects of errors involved in the multiple-wavelength anomalous diffraction (MAD) method. This probability distribution, derived from those of the intensities, is two-dimensional for acentric reflections and uni-dimensional for centric reflections. It permits, using the centroid of the distribution, the calculation of the modulus and the phase of the `best' structure factor. The procedure for extracting the phase and its figure of merit is presented. Tests performed on simulated data show the contribution of this method with respect to other methods which use a distribution of only the phase as a function of the error of closure.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 55 (1999), S. 1591-1593 
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The catabolic ornithine carbamoyltransferase (OTCase) from Pseudomonas aeruginosa exhibits allosteric behaviour, with two conformational states of the molecule: an active R form and an inactive T form. The enzyme is a dodecamer with a molecular mass of 455700 Da. Three crystal forms have been obtained. Crystals of allosteric state T are rhombohedral, belonging to the R3 space group, with hexagonal unit-cell parameters a = b = 180.6, c = 122.0 Å. They diffract to a resolution of 4.5 Å. Two crystal forms for allosteric state R have been obtained, with hexagonal and cubic symmetries. Hexagonal crystals, which diffract to a resolution of 3.4 Å, belong to the space group P63 with unit-cell parameters a = b = 140.8, c = 145.6 Å. The cubic crystals belong to space group I23, with unit-cell parameter a = 134.32 Å and diffract to a resolution better than 2.5 Å. In all crystal forms, the dodecamer exhibits a 23 point-group symmetry.
    Type of Medium: Electronic Resource
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