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  • Articles  (64)
  • 1985-1989  (30)
  • 1980-1984  (23)
  • 1965-1969  (11)
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  • 1
    Electronic Resource
    Electronic Resource
    Remarks on a Markov chain example of Kolmogorov (1969)
    Springer
    Probability theory and related fields 13 (1969), S. 315-320 
    Details
    ISSN: 1432-2064
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary It is shown that the stochastic transition matrix P(t), in Kolmogorov's example of a process with an instantaneous state, is uniquely determined by the derivative matrix Q=P′(0), and the most general such substochastic P(t) is also found. The example is used to show that, if 0 is an instantaneous state, then 1-p 00(t) can tend to 0 arbitrarily slowly and on the other hand (1-p 00 (t))/t can tend to +t8 arbitrarily slowly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00539207
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  • 2
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    "The Workingman In American Life". By John Laslett (Book Review) (1969)
    Ithaca, N.Y. : Periodicals Archive Online (PAO)
    Industrial and Labor Relations Review. 22:4 (1969:July) 625 
    Details
    ISSN: 0019-7939
    Topics: Economics
    Description / Table of Contents: Labor Organizations
    Notes: BOOK REVIEWS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3121-1969-022-04-000024
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  • 3
    Electronic Resource
    Electronic Resource
    Functional properties of the heterochromatic sequences inducing w m4 position-effect variegation in Drosophila melanogaster (1985)
    Springer
    Chromosoma 93 (1985), S. 132-139 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In position-effect variegation euchromatic genes are brought into the vicinity of heterochromatic sequences as a result of chromosomal rearrangements. This results in the inactivation of these genes in a proportion of cells causing a variegated phenotype. Tartof et al. (1984) have shown that the flanking heterochromatin in the w m4 variegating rearrangement in Drosophila melanogaster is homologous to the Type I inserts found in some portions of the rDNA repeats. We have studied the functional properties of these sequences using 51 revertant chromosomes, several variant lines of w m4 , strong enhancer mutations of position-effect variegation and X heterochromatin deletions. Our results suggest an array of tandemly repeated sequences showing additive effects and probably subject to magnification and reduction in number. Since only 3 of the 51 revertants isolated do not show variegation if strong enhancer mutations are introduced, only a very short sequence must be essential for the induction of white gene inactivation in w m4 . This suggests that the heterochromatic junction itself is sufficient to initiate the variegation of an adjacent gene. Parental source as well as paternal effects on the activity of these sequences have been detected. Revertant chromosomes of w m4 can be found after P-directed mutagenesis in hybrid dysgenic crosses suggesting mobile genetic elements at the breakpoints of inversion w m4 . These results are discussed with respect to the structural basis of positioneffect variegation as well as the function of certain heterochromatic sequences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293160
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  • 4
    Electronic Resource
    Electronic Resource
    Suppressor mutation of position-effect variegation in Drosophila melanogaster affecting chromatin properties (1986)
    Springer
    Chromosoma 93 (1986), S. 398-403 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The dominant mutation Su-var(2)1 01 which suppresses position-effect variegation and displays recessive butyrate sensitivity was found to result in significant hyperacetylation of histone H4. This biochemical finding, as well as the genetic properties of this mutation, strongly suggest that the wild-type product of the corresponding locus is involved in histone H4 deacetylation. In larvae containing the suppressor mutation the accessibility of chromatin to endogenous nucleases is significantly increased which might be causally connected with histone H4 hyperacetylation. The suppressor mutation Su-var(2)1 01 has, therefore, to be classified as a chromatin condensation mutation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00285820
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  • 5
    Electronic Resource
    Electronic Resource
    Mutants affecting position-effect heterochromatinization in Drosophila melanogaster (1982)
    Springer
    Chromosoma 85 (1982), S. 539-551 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The dominant suppressor Su(var)b 101 and the dominant enhancer En(var)c 101 were found to affect significantly white variegation in a strongly variegating line of the w m4 chromosome (w m4h ) which has been used as standard rearrangement for a genetic dissection of position-effect variegation (Reuter and Wolff, 1981). Both mutations were also shown to affect position-effect heterochromatisation in T(1;4)w m258-21 and variegation in all the rearrangements tested (white, brown, scute and bobbed variegation). These results suggest that the genes identified encode functions essential for the manifestation of gene inactivation in position-effect rearrangements. It seems also reasonable to assume that in all the rearrangements tested identical heterochromatisation processes lead to inactivation of the genes whose phenotype is variegated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00327349
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  • 6
    Electronic Resource
    Electronic Resource
    Characterization of two ornithine carbamoyltransferases from Pseudomonas syringae pv. phaseolicola, the producer of phaseolotoxin (1987)
    Springer
    Archives of microbiology 147 (1987), S. 174-178 
    Details
    ISSN: 1432-072X
    Keywords: Pseudomonas syringae pv. phaseolicola ; Ornithine carbamoyltransferases ; Phaseolotoxin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Two ornithine carbamoyltransferases (OCT 1 and OCT 2) were isolated from Pseudomonas syringae pv. phaseolicola and purified by precipitation with ammonium sulfate, heat denaturation, chromatography on DEAE-Sephadex A-50 and Sephadex G-200. Molecular weights of both enzymes: 110,000; optimal activity: pH 8.5 to 9.5 (OCT 1), pH 8.4 (OCT 2); apparent K m for ornithine: 7·10-4 (both enzymes); apparent K m for carbamoylphosphate: 7·10-4 (OCT 1), 2.8·10-3 (OCT 2). Both enzymes possess only an anabolic function. OCT 1 is highly inhibited by low concentrations of phaseolotoxin and Orn-P(O)(NH2)-NH-SO3H, OCT 2 is insensitive to both compounds. The inhibition of OCT 1 is reversible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00415280
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  • 7
    Electronic Resource
    Electronic Resource
    Sialic acid-containing lipopolysaccharides in purple nonsulfur bacteria (1988)
    Springer
    Archives of microbiology 150 (1988), S. 584-589 
    Details
    ISSN: 1432-072X
    Keywords: Lipopolysaccharide ; Sialic acids ; Core region ; Purple nonsulfur bacteria ; N-Acetylneuraminic acid ; Rhodobacter
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Lipopolysaccharides (LPS) from a number of purple nonsulfur bacteria and of phylogenetically related species were analyzed for the presence of sialic acid by gas chromatography/mass spectrometry. Species and strains of the genera Rhodobacter, Rhodopseudomonas, Rhodomicrobium, Rhodospirillum, Rhodocyclus and Rhodopila were investigated, sialic acid, however, was found only in the genus Rhodobacter. It occurs in strains of Rhodobacter capsulatus, R. sphaeroides, R. sulfidophilus and R. veldkampii. All these species belong to the α-3 subgroup of purple bacteria as defined by 16S rRNA catalogues. Approximately equimolar ratios of sialic acid and of 2-keto-3-deoxy-octonate (KDO) were found in isolated LPSs. Sodium deoxycholate gel electrophoresis of these LPS-samples also suggested a location of sialic acid in the LPS “core” region. Sialic acid was present only in those LPSs, which exhibited a “complete core region”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408254
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  • 8
    Electronic Resource
    Electronic Resource
    Note on resolvents of denumerable submarkovian processe (1967)
    Springer
    Probability theory and related fields 9 (1967), S. 16-19 
    Details
    ISSN: 1432-2064
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00535463
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  • 9
    Electronic Resource
    Electronic Resource
    Third chromosome suppressor of position-effect variegation loci in Drosophila melanogaster (1986)
    Springer
    Molecular genetics and genomics 202 (1986), S. 481-487 
    Details
    ISSN: 1617-4623
    Keywords: Position-effect variegation ; Suppressor mutations ; Chromosome 3 ; Heterochromatin ; Drosophila melanogaster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary As a result of a genetic analysis of 63 third chromosome suppressor mutations of position-effect variegation 12 different loci showing dominant suppression have been identified and their map positions determined. A compilcation of the genetic data available for each suppressor locus is given. The strong suppressor effects of the mutations have been quantified by measurements of white variegation inw m4h /w m4h ,w m4h /Y andw m4h /O flies. Mutant alleles of three loci were found in these studies to dominate over the strong enhancer effect of complete loss of the Y chromosome. Most of the identified loci suppressing position-effect variegation represent essential genetic funtions; only three loci represent nonessential functions. Mutations of two loci display recessive butyrate sensitivity and lethal interaction with the heterochromatic Y chromosome suggesting that these genes affect chromosomal condensation. Studies with deficiencies and triploids revealed that most of the loci represent haplo-abnormal suppressor functions. The use of the isolated mutant material for genetic, developmental and molecular studies of processes connected with gene inactivation in position-effect variegation is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00333281
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  • 10
    Electronic Resource
    Electronic Resource
    Butyrate sensitive suppressor of position-effect variegation mutations in drosophila melanogaster (1982)
    Springer
    Molecular genetics and genomics 188 (1982), S. 480-485 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Mutations at a locus on chromosome II of D. melanogaster suppressing position-effect variegation mutations have been identified which display recessive butyrate sensitivity. Survival of homozygous mutant flies is significantly reduced on medium containing sodium n-butyrate. The butyrate sensitive suppressor mutations are further characterized by recessive female sterility and reduced survival of homozygotes. Complementation analysis showed their allelism. The locus of these mutations, Su-var (2) 1, has been localized to 40.5±0.2 and, by using interstitial duplications, to region 31CD on the cytogenetic map. Moreover, the mutant alleles of the Su-var (2) 1 locus display a lethal interaction with the heterochromatic Y chromosome. The presence or absence of a Y chromosome in males or females has a strong influence on the viability of homozygous or transheterozygous suppressor flies. All the genetic properties of Su-var (2) 1 mutants suggest strongly that this locus affects chromosome condensation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00330052
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