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  • COMPUTER OPERATIONS AND HARDWARE  (2)
  • Polyphosphoinositides  (2)
  • Ethanol  (1)
  • Signal transduction
  • 1990-1994  (5)
  • 1
    Publikationsdatum: 2019-06-28
    Beschreibung: The Advanced Control Technology Branch of the NASA Lewis Research Center performs research in the area of advanced digital controls for aeronautic and space propulsion systems. This work requires the real-time implementation of both control software and complex dynamical models of the propulsion system. We are implementing these systems in a distributed, multi-vendor computer environment. Therefore, a need exists for real-time communication and synchronization between the distributed multi-vendor computers. A shared memory network is a potential solution which offers several advantages over other real-time communication approaches. A candidate shared memory network was tested for basic performance. The shared memory network was then used to implement a distributed simulation of a ramjet engine. The accuracy and execution time of the distributed simulation was measured and compared to the performance of the non-partitioned simulation. The ease of partitioning the simulation, the minimal time required to develop for communication between the processors and the resulting execution time all indicate that the shared memory network is a real-time communication technique worthy of serious consideration.
    Schlagwort(e): COMPUTER OPERATIONS AND HARDWARE
    Materialart: NASA-TM-106239 , E-7969 , NAS 1.15:106239 , AVSCOM-TR-92-C-020 , AD-A268827
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    facet.materialart.
    Unbekannt
    In:  CASI
    Publikationsdatum: 2019-07-13
    Beschreibung: A laboratory testbed facility which was constructed at NASA LeRC for the development of an Intelligent Control System (ICS) for reusable rocket engines is described. The framework of the ICS consists of a hierarchy of various control and diagnostic functions. The traditional high speed, closed-loop controller resides at the lowest level of the ICS hierarchy. Above this level resides the diagnostic functions which identify engine faults. The ICS top level consists of the coordination function which manages the interaction between an expert system and a traditional control system. The purpose of the testbed is to demonstrate the feasibility of the OCS concept by implementing the ICS as the primary controller in a simulation of the Space Shuttle Main Engine (SSME). The functions of the ICS which are implemented in the testbed are as follows: an SSME dynamic simulation with selected fault mode models, a reconfigurable controller, a neural network for sensor validation, a model-based failure detection algorithm, a rule based failure detection algorithm, a diagnostic expert system, an intelligent coordinator, and a user interface which provides a graphical representation of the event occurring within the testbed. The diverse nature of the ICS has led to the development of a distributed architecture consisting of specialized hardware and software for the implementation of the various functions. This testbed is made up of five different computer systems. These individual computers are discussed along with the schemes used to implement the various ICS components. The communication between computers and the timing and synchronization between components are also addressed.
    Schlagwort(e): COMPUTER OPERATIONS AND HARDWARE
    Materialart: NASA-TM-105795 , E-7225 , NAS 1.15:105795 , AVSCOM-TR-92-C-014 , AD-A255413 , 1992 Advanced Earth-to-Orbit Propulsion Technology Conference; May 19, 1992 - May 21, 1992; Huntsville, AL; United States
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Planta 193 (1994), S. 89-98 
    ISSN: 1432-2048
    Schlagwort(e): Dianthus ; Phosphatidylinositol 3-phosphate ; Phospholipid turnover ; Polyphosphoinositides ; Signal transduction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Carnation (Dianthus caryophyllus L. cv. White Sim) petal discs were radiolabelled with [32P]orthophosphate and the lipids were extracted and analysed by thin-layer chromatography and autoradiography. Phospholipids were identified by co-migration with standards using thin-layer chromatography with different solvent systems. Results showed that [32P]orthophosphate was rapidly incorporated into the minor lipids phosphatidic acid (PtdOH), phosphatidylinositol monophosphate (PtdInsP) and phosphatidylinositol bisphosphate (PtdInsP2), and relatively slowly into the structural lipids phosphatidylcholine, -ethanolamine, -glycerol and -inositol. Pulse-chase experiments revealed that the label was rapidly lost from PtdOH, PtdInsP and PtdInsP2 while the structural lipids remained radiolabelled. The amount of PtdInsP and PtdInsP2 was found to constitute 0.45% and 0.013%, respectively, of the total phospholipids, on a molar basis. Together these results show that the turnover of the chemically low-abundant polyphosphoinositides is relatively high compared with the major structural phospholipids. Phosphatidylinositol monophosphate was further characterized by showing that it incorporates myo[3H]inositol and that its major fatty-acid constituents are palmitic acid and linoleic acid. Furthermore, we present evidence for the presence of both phosphatidylinositol 3-phosphate and phosphatidylinositol 4-phosphate isomers. The significance of these results is discussed with respect to plant phosphoinositide signal transduction.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    ISSN: 1432-2048
    Schlagwort(e): Chlamydomonas ; Gamete (activation) ; Ethanol ; Inositol 1,4,5-trisphosphate ; Phospholipid turnover ; Signalling
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Alcohols induce mating-structure activation in Chlamydomonas eugametos gametes. From the effect of ethanol on the 32P-labelling of polyphosphoinositides, we conclude that the synthesis of these lipids is stimulated. Biologically inactive concentrations of ethanol (〈6%) had no effect on synthesis, but 6–8% ethanol stimulated synthesis for upto 60 min. The 32P incorporated into polyphosphoinositides and phosphatidic acid during ethanol treatment was readily chased out when 1 mM unlabelled Na3PO4 was added. Using a binding assay for inositol 1,4,5-trisphosphate, we show that the production of this phospholipid constituent is dramatically increased after ethanol treatment. This effect, coupled to a rise in intracellular calcium concentration, could explain gamete activation. The significance of these results in explaining other ethanol-induced phenomena in algae is discussed.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    ISSN: 1432-2048
    Schlagwort(e): Chlamydomonas ; Fertilization ; Gamete fusion ; Inositol 1,4,5-trisphospate ; Plant cell-signalling ; Polyphosphoinositides
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Within the first 2 h of sexual reproduction, gametes of the green alga Chlamydomonas eugametos agglutinate, fuse via their mating structures, de-agglutinate and swim off as vis-à-vis pairs. During this period, increases in intracellular inositol 1,4,5-trisphosphate levels and changes in polyphosphoinositide synthesis were associated with cell fusion. The protein-kinase-C inhibitor staurosporine (0.1–0.2 μM) inhibited the de-agglutination of pairs and therefore prevented them swimming away, while earlier stages of mating such as agglutination or cell fusion were unaffected. The results suggest that inositol 1,4,5-trisphosphate and diacylglycerol are fertilization signals in C. eugametos. The idea that they could also be fertilization signals in higher plants is discussed in relation to in vitro embryogenesis.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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