ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Life Sciences (General)  (2)
  • transient flow fields  (2)
  • Humans
  • 1995-1999  (5)
  • 1
    facet.materialart.
    Unbekannt
    Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1 (1998)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1998-03-21
    Beschreibung: The sphingolipid metabolite sphingosine-1-phosphate (SPP) has been implicated as a second messenger in cell proliferation and survival. However, many of its biological effects are due to binding to unidentified receptors on the cell surface. SPP activated the heterotrimeric guanine nucleotide binding protein (G protein)-coupled orphan receptor EDG-1, originally cloned as Endothelial Differentiation Gene-1. EDG-1 bound SPP with high affinity (dissociation constant = 8.1 nM) and high specificity. Overexpression of EDG-1 induced exaggerated cell-cell aggregation, enhanced expression of cadherins, and formation of well-developed adherens junctions in a manner dependent on SPP and the small guanine nucleotide binding protein Rho.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, M J -- Van Brocklyn, J R -- Thangada, S -- Liu, C H -- Hand, A R -- Menzeleev, R -- Spiegel, S -- Hla, T -- DK45659/DK/NIDDK NIH HHS/ -- GM43880/GM/NIGMS NIH HHS/ -- HL49094/HL/NHLBI NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1998 Mar 6;279(5356):1552-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, University of Connecticut School of Medicine, Farmington, CT 06030, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9488656" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Cadherins/*biosynthesis ; *Cell Aggregation ; Cell Differentiation ; Cell Line ; Cloning, Molecular ; GTP-Binding Proteins/metabolism ; Gene Expression ; Genes, Immediate-Early ; Humans ; Immediate-Early Proteins/genetics/*metabolism ; Intercellular Junctions/*ultrastructure ; Ligands ; *Lysophospholipids ; Mitogen-Activated Protein Kinase 1/metabolism ; Morphogenesis ; Receptors, Cell Surface/genetics/*metabolism ; *Receptors, G-Protein-Coupled ; Receptors, Lysophospholipid ; Signal Transduction ; Sphingosine/*analogs & derivatives/metabolism ; Transfection ; rho GTP-Binding Proteins
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    AKTUELLE ARTIKEL
  • 2
    Digitale Medien
    Digitale Medien
    Digital imaging characterization of the kinematics of water-sediment interaction (1997)
    Springer
    Water, air & soil pollution 99 (1997), S. 173-177 
    Details
    ISSN: 1573-2932
    Schlagwort(e): sediment transport ; transient flow fields ; laboratory measurements ; digital patricle tracking velocimetry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Energietechnik
    Notizen: Abstract Digital imaging techniques especially geared towards the laboratory characterization of the kinematics of water-sediment interaction are presented. More specifically, the methods proposed apply to the motion of cohesionless spherical particles in transient water flow, with the aim of obtaining both particle velocity and concentration fields from sequences of digital images. A special particle identification algorithm is devised in order to deal with densely packed particles (in contrast to the sparase seedings of tracers used in studies of pure fluid kinematics) and to allow application of digital particle tracking velocimetry (DPTV). A procedure for extracting the concentration field from the knowledge of the discrete positions is then detailed. Finally, the various tools are illustrated for the laboratory case of a dambreak wave over a movable bed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02406856
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Digital Imaging Characterization of the Kinematics of Water-Sediment Interaction (1997)
    Springer
    Water, air & soil pollution 99 (1997), S. 173-177 
    Details
    ISSN: 1573-2932
    Schlagwort(e): sediment transport ; transient flow fields ; laboratory measurements ; digital particle tracking velocimetry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Energietechnik
    Notizen: Abstract Digital imaging techniques especially geared towards the laboratory characterization of the kinematics of water-sediment interaction are presented. More specifically, the methods proposed apply to the motion of cohesionless spherical particles in transient water flow, with the aim of obtaining both particle velocity and concentration fields from sequences of digital images. A special particle identification algorithm is devised in order to deal with densely packed particles (in contrast to the sparse seedings of tracers used in studies of pure fluid kinematics) and to allow application of digital particle tracking velocimetry (DPTV). A procedure for extracting the concentration field from the knowledge of the discrete particle positions is then detailed. Finally, the various tools are illustrated for the laboratory case of a dambreak wave over a movable bed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1018305004205
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 4
    facet.materialart.
    Unbekannt
    Effects of microgravity on urinary osteopontin (1999)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-07-13
    Beschreibung: Increased risk of renal stone formation during space flight has been linked primarily to increased calcium excretion from bone demineralization induced by space flight. Other factors contributing to increased risk include increased urinary calcium oxalate supersaturation, while urinary citrate, magnesium and volume are all decreased. The aim of this study was to increase the predictive value of stone risk profiles for crew members during space flight by evaluating the excretion of urinary protein inhibitors of calcium crystallization so that more comprehensive stone risk profiles could relate mineral saturation to the concentrations of inhibitor proteins. Levels of urinary osteopontin (uropontin) are reported in a series of 14 astronauts studied before, during, and after space flights. During space flight, a compensatory increase in uropontin excretion was not observed. However, the uropontin excretion of a majority of astronauts was increased during the period after space flight and was maximal at 2 wk after landing. The downward shift in the molecular size of uropontin observed in samples obtained during space flight was shown to result from storage at ambient temperature during flight, rather than an effect of microgravity on uropontin synthesis.
    Schlagwort(e): Life Sciences (General)
    Materialart: Journal of the American Society of Nephrology : JASN (ISSN 1046-6673); 10 Suppl 14; S389-93
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 5
    facet.materialart.
    Unbekannt
    Composite x-ray image assembly for large-field digital mammography with one- and two-dimensional positioning of a focal plane array (1998)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-07-13
    Beschreibung: To demonstrate the feasibility of a novel large-field digital mammography technique, a 1024 x 1024 pixel Loral charge-coupled device (CCD) focal plane array (FPA) was positioned in a mammographic field with one- and two-dimensional scan sequences to obtain 950 x 1800 pixel and 3600 x 3600 pixel composite images, respectively. These experiments verify that precise positioning of FPAs produced seamless composites and that the CCD mosaic concept has potential for high-resolution, large-field imaging. The proposed CCD mosaic concept resembles a checkerboard pattern with spacing left between the CCDs for the driver and readout electronics. To obtain a complete x-ray image, the mosaic must be repositioned four times, with an x-ray exposure at each position. To reduce the patient dose, a lead shield with appropriately patterned holes is placed between the x-ray source and the patient. The high-precision motorized translation stages and the fiber-coupled-scintillating-screen-CCD sensor assembly were placed in the position usually occupied by the film cassette. Because of the high mechanical precision, seamless composites were constructed from the subimages. This paper discusses the positioning, image alignment procedure, and composite image results. The paper only addresses the formation of a seamless composite image from subimages and will not consider the effects of the lead shield, multiple CCDs, or the speed of motion.
    Schlagwort(e): Life Sciences (General)
    Materialart: Medical physics (ISSN 0094-2405); 25; 2; 172-5
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...