ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles  (13)
  • Animals  (9)
  • Engineering  (4)
  • Nuclear reactions
  • 1995-1999  (13)
Collection
  • Articles  (13)
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 39 (1996), S. 1635-1657 
    ISSN: 0029-5981
    Keywords: finite element method ; radiation boundary conditions ; absorbing boundary conditions ; discontinuous Galerkin method ; structural acoustics ; wave equation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A time-discontinuous Galerkin space-time finite element method is formulated for the exterior structural acoustics problem in two space dimensions. The problem is posed over a bounded computational domain with local time-dependent radiation (absorbing) boundary conditions applied to the fluid truncation boundary. Absorbing boundary conditions are incorporated as ‘natural’ boundary conditions in the space-time variational equation, i.e. they are enforced weakly in both space and time. Following Bayliss and Turkel, time-dependent radiation boundary conditions for the two-dimensional wave equation are developed from an asymptotic approximation to the exact solution in the frequency domain expressed in negative powers of a non-dimensional wavenumber. In this paper, we undertake a brief development of the time-dependent radiation boundary conditions, establishing their relationship to the exact impedance (Dirichlet-to-Neumann map) for the acoustic fluid, and characterize their accuracy when implemented in our space-time finite element formulation for transient structural acoustics. Stability estimates are reported together with an analysis of the positive form of the matrix problem emanating from the space-time variational equations for the coupled fluid-structure system. Several numerical simulations of transient radiation and scattering in two space dimensions are presented to demonstrate the effectiveness of the space-time method.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 38 (1995), S. 371-397 
    ISSN: 0029-5981
    Keywords: Helmholtz equation ; least squares ; Galerkin method ; Fourier analysis ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: In this paper a Galerkin least-squares (GLS) finite element method, in which residuals in least-squares form are added to the standard Galerkin variational equation, is developed to solve the Helmholtz equation in two dimensions. An important feature of GLS methods is the introduction of a local mesh parameter that may be designed to provide accurate solutions with relatively coarse meshes. Previous work has accomplished this for the one-dimensional Helmholtz equation using dispersion analysis. In this paper, the selection of the GLS mesh parameter for two dimensions is considered, and leads to elements that exhibit improved phase accuracy. For any given direction of wave propagation, an optimal GLS mesh parameter is determined using two-dimensional Fourier analysis. In general problems, the direction of wave propagation will not be known a priori. In this case, an optimal GLS parameter is found which reduces phase error for all possible wave vector orientations over elements. The optimal GLS parameters are derived for both consistent and lumped mass approximations. Several numerical examples are given and the results compared with those obtained from the Galerkin method. The extension of GLS to higher-order quadratic interpolations is also presented.
    Additional Material: 20 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 28 (1998), S. 1217-1239 
    ISSN: 0271-2091
    Keywords: multiphase ; multifluid ; multigrid ; FAS ; local coupled solver ; Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In recent years multigrid algorithms have been applied to increasingly difficult systems of partial differential equations and major improvements in both speed of convergence and robustness have been achieved. Problems involving several interacting fluids are of great interest in many industrial applications, especially in the process and petro-chemical sectors. However, the multifluid version of the Navier-Stokes equations is extremely complex and represents a challenge to advanced numerical algorithms. In this paper, we describe an extension of the full approximation storage (FAS) multigrid algorithm to the multifluid equations. A number of special issues had to be addressed. The first was the development of a customised, non-linear, coupled relaxation scheme for the smoothing step. Automatic differentiation was used to facilitate the coding of a robust, globally convergent quasi-Newton method. It was also necessary to use special inter-grid transfer operators to maintain the realisability of the solution. Algorithmic details are given and solutions for a series of test problems are compared with those from a widely validated, commercial code. The new approach has proved to be robust; it achieves convergence without resorting to specialised initialisation methods. Moreover, even though the rate of convergence is complex, the method has achieved very good reduction factors: typically five orders of magnitude in 50 cycles. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 24 (1997), S. 355-373 
    ISSN: 0271-2091
    Keywords: computational fluid dynamics ; transonic airfoils ; numerical uncertainty ; Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Numerical uncertainties are quantified for calculations of transonic flow around a divergent trailing edge (DTE) supercritical aerofoil. The Reynolds-averaged Navier-Stokes equations are solved using a linearized block implicit solution procedure and mixing-length turbulence model. This procedure has reproduced measurements around supercritical aerofoils with blunt trailing edges that have shock, boundary layer and separated regions. The present effort quantifies numerical uncertainty in these calculations using grid convergence indices which are calculated from aerodynamic coefficients, shock location, dimensions of the recirculating region in the wake of the blunt trailing edge and distributions of surface pressure coefficients. The grid convergence index is almost uniform around the aerofoil, except in the shock region and at the point where turbulence transition was fixed. The grid convergence index indicates good convergence for lift but only fair convergence for moment and drag and also confirms that drag calculations are more sensitive to numerical error. © 1997 by John Wiley and Sons, Ltd.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 1998-12-18
    Description: CTLA-4, a negative regulator of T cell function, was found to associate with the T cell receptor (TCR) complex zeta chain in primary T cells. The association of TCRzeta with CTLA-4, reconstituted in 293 transfectants, was enhanced by p56(lck)-induced tyrosine phosphorylation. Coexpression of the CTLA-4-associated tyrosine phosphatase, SHP-2, resulted in dephosphorylation of TCRzeta bound to CTLA-4 and abolished the p56(lck)-inducible TCRzeta-CTLA-4 interaction. Thus, CTLA-4 inhibits TCR signal transduction by binding to TCRzeta and inhibiting tyrosine phosphorylation after T cell activation. These findings have broad implications for the negative regulation of T cell function and T cell tolerance.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, K M -- Chuang, E -- Griffin, M -- Khattri, R -- Hong, D K -- Zhang, W -- Straus, D -- Samelson, L E -- Thompson, C B -- Bluestone, J A -- P01 AI35294-6/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1998 Dec 18;282(5397):2263-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Ben May Institute for Cancer Research, and Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9856951" target="_blank"〉PubMed〈/a〉
    Keywords: Abatacept ; Animals ; Antigens, CD ; Antigens, Differentiation/*metabolism ; CTLA-4 Antigen ; Cell Line ; Cells, Cultured ; Humans ; *Immunoconjugates ; Intracellular Signaling Peptides and Proteins ; *Lymphocyte Activation ; Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/genetics/metabolism ; Membrane Proteins/*metabolism ; Mice ; Mice, Inbred BALB C ; Models, Immunological ; Phosphorylation ; Phosphotyrosine/metabolism ; Protein Tyrosine Phosphatase, Non-Receptor Type 11 ; Protein Tyrosine Phosphatase, Non-Receptor Type 6 ; Protein Tyrosine Phosphatases/genetics/metabolism ; Receptors, Antigen, T-Cell/*metabolism ; Recombinant Fusion Proteins/metabolism ; SH2 Domain-Containing Protein Tyrosine Phosphatases ; *Signal Transduction ; T-Lymphocytes/*immunology ; Transfection ; src Homology Domains
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Publication Date: 1999-02-05
    Description: The abnormally high number of centrosomes found in many human tumor cells can lead directly to aneuploidy and genomic instability through the formation of multipolar mitotic spindles. To facilitate investigation of the mechanisms that control centrosome reproduction, a frog egg extract arrested in S phase of the cell cycle that supported repeated assembly of daughter centrosomes was developed. Multiple rounds of centrosome reproduction were blocked by selective inactivation of cyclin-dependent kinase 2-cyclin E (Cdk2-E) and were restored by addition of purified Cdk2-E. Confocal immunomicroscopy revealed that cyclin E was localized at the centrosome. These results demonstrate that Cdk2-E activity is required for centrosome duplication during S phase and suggest a mechanism that could coordinate centrosome reproduction with cycles of DNA synthesis and mitosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hinchcliffe, E H -- Li, C -- Thompson, E A -- Maller, J L -- Sluder, G -- New York, N.Y. -- Science. 1999 Feb 5;283(5403):851-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9933170" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Aphidicolin/pharmacology ; Blastomeres/chemistry ; *CDC2-CDC28 Kinases ; *Cell Cycle Proteins ; Cell Extracts ; Centrosome/chemistry/*metabolism ; Cyclin E/analysis/*metabolism ; Cyclin-Dependent Kinase 2 ; Cyclin-Dependent Kinase Inhibitor p27 ; Cyclin-Dependent Kinases/antagonists & inhibitors/*metabolism ; DNA/biosynthesis ; Enzyme Inhibitors/pharmacology ; Microscopy, Confocal ; Microscopy, Fluorescence ; Microscopy, Video ; Microtubule-Associated Proteins/pharmacology ; Ovum ; Protein Kinases/metabolism ; Protein-Serine-Threonine Kinases/antagonists & inhibitors/*metabolism ; Proteins ; Recombinant Proteins/pharmacology ; *S Phase ; *Tumor Suppressor Proteins ; Xenopus ; Xenopus Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    facet.materialart.
    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-06-26
    Description: Interactions between species are as evolutionarily malleable as the species themselves and have played a central role in the diversification and organization of life. This malleability creates complex geographic mosaics in interspecific interactions that can evolve rapidly over decades, blurring the distinction between evolutionary time and ecological time and making the study of coevolution crucial for human health and welfare.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thompson, J N -- New York, N.Y. -- Science. 1999 Jun 25;284(5423):2116-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departments of Botany and Zoology, Washington State University, Pullman, WA 99164, USA. jnt@wsu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10381869" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Evolution ; Drug Resistance, Microbial ; *Ecosystem ; Humans ; Models, Biological ; Parasites/pathogenicity ; *Selection, Genetic ; Virulence/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    Publication Date: 1999-01-29
    Description: A carbapenem antibiotic, L-786,392, was designed so that the side chain that provides high-affinity binding to the penicillin-binding proteins responsible for bacterial resistance was also the structural basis for ameliorating immunopathology. Expulsion of the side chain upon opening of the beta-lactam ring retained antibacterial activity while safely expelling the immunodominant epitope. L-786,392 was well tolerated in animal safety studies and had significant in vitro and in vivo activities against methicillin- and vancomycin-resistant Staphylococci and vancomycin-resistant Enterococci.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rosen, H -- Hajdu, R -- Silver, L -- Kropp, H -- Dorso, K -- Kohler, J -- Sundelof, J G -- Huber, J -- Hammond, G G -- Jackson, J J -- Gill, C J -- Thompson, R -- Pelak, B A -- Epstein-Toney, J H -- Lankas, G -- Wilkening, R R -- Wildonger, K J -- Blizzard, T A -- DiNinno, F P -- Ratcliffe, R W -- Heck, J V -- Kozarich, J W -- Hammond, M L -- New York, N.Y. -- Science. 1999 Jan 29;283(5402):703-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Merck Research Laboratories, Rahway, NJ 07065, USA. hugh_rosen@merck.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9924033" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies/blood ; *Bacterial Proteins ; Carbapenems/chemistry/*immunology/metabolism/*pharmacology/toxicity ; Carrier Proteins/metabolism ; Dipeptidases/metabolism ; *Drug Design ; Drug Resistance, Microbial ; Drug Resistance, Multiple ; Enterococcus/drug effects ; Erythrocytes/immunology ; Haptens ; *Hexosyltransferases ; Humans ; Immunodominant Epitopes ; Immunoglobulin G/blood ; Lactams/chemical synthesis/chemistry/metabolism/*pharmacology ; Lymphocyte Activation ; Macaca mulatta ; Mice ; Mice, Inbred DBA ; Microbial Sensitivity Tests ; Muramoylpentapeptide Carboxypeptidase/metabolism ; Penicillin-Binding Proteins ; *Peptidyl Transferases ; Staphylococcal Infections/drug therapy ; Staphylococcus/drug effects ; Thiazoles/chemical synthesis/chemistry/metabolism/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    Publication Date: 1998-02-07
    Description: The behavioral phenomenon of blocking indicates that the informational relationship between the conditioned stimulus and the unconditioned stimulus is essential in classical conditioning. The eyeblink conditioning paradigm is used to describe a neural mechanism that mediates blocking. Disrupting inhibition of the inferior olive, a structure that conveys unconditioned stimulus information (airpuff) to the cerebellum prevented blocking in rabbits. Recordings of cerebellar neuronal activity show that the inferior olive input to the cerebellum becomes suppressed as learning occurs. These results suggest that the inferior olive becomes functionally inhibited by the cerebellum during conditioning, and that this negative feedback process might be the neural mechanism mediating blocking.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kim, J J -- Krupa, D J -- Thompson, R F -- AF05142/AF/ACF HHS/ -- New York, N.Y. -- Science. 1998 Jan 23;279(5350):570-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neuroscience Program, University of Southern California, Los Angeles, CA 90089-2520, USA. jeansok.kim@yale.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9438852" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Blinking ; Cerebellum/*physiology ; *Conditioning, Classical ; Evoked Potentials ; Feedback ; Neural Pathways ; Olivary Nucleus/*physiology ; Picrotoxin/pharmacology ; Purkinje Cells/*physiology ; Rabbits ; gamma-Aminobutyric Acid/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    facet.materialart.
    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1995-07-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thompson, C -- New York, N.Y. -- Science. 1995 Jul 21;269(5222):301-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7618098" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carrier Proteins/chemistry/genetics/*immunology ; Child ; Cloning, Molecular ; Complement Activation/*immunology ; Disease Susceptibility ; Humans ; *Immunity, Innate ; Immunologic Deficiency Syndromes/*etiology ; Mannose-Binding Lectins ; Mutation ; Phagocytosis/*immunology ; Protein Conformation ; Protein Structure, Secondary
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...