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  • 1995-1999  (33)
  • 1990-1994  (16)
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  • 1
    Electronic Resource
    Electronic Resource
    High-Sulfur Protein Gene Expression in a Transgenic Mouse (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 642 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb24377.x
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  • 2
    Electronic Resource
    Electronic Resource
    Saisonale Veränderungen in der Zusammensetzung der Nahrung beim Neuntöter (Lanius collurio) (1993)
    Springer
    Journal of ornithology 134 (1993), S. 1-11 
    Details
    ISSN: 1439-0361
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary The remains of prey in 293 pellets of the Red-backed Shrike, collected 1990 and 1991 in NW-Germany, consisted on average of 51,3% Coleoptera, 37,2% Hymenoptera, 5,0% Saltatoria, 2,7% Diptera, 1,5% Lepidoptera and 0,9% vertebrates. Generally, the part of extremly scleroticized insects was high. Careful and thorough pellet-analyses of the Red-backed Shrike can be used for quantitative studies with tolerable error. The pellets were all found on pasture-ground; thus they are comparable concerning their contents. From May to August the percentage of Coleoptera increased, whereas the part of Hymenoptera decreased constantly. Other arthropods as well as vertebrates could be found in constant parts. The decreasing number of beetles is due to the decline of coprophile species, mainlyAphodius fossor (Scarabaeidae). The inclining number of Hymenoptera may find an explanation in the increasing abundance of eusocial bumble-bees and wasps in the course of summer. The minimal size of the Red-backed Shrike's prey is about 4 mm. Smaller prey is only caught when appearing in large amounts like ants. The Red-backed Shrike is an unspecialized hunter of small prey. The optimal prey is big, abundant and easy to hunt.
    Notes: Zusammenfassung Die Beutetierreste aus 293 Gewöllen des Neuntöters, gesammelt 1990 und 1991 in 10 Jahresrevieren in Nordrhein-Westfalen ergaben im Mittel aller Aufsammlungsorte 51,3 Individuen-% Käfer, 37,2% Hautflügler, 5,0% Springschrecken, 2,7% Zweiflügler, 1,5% Schmetterlinge und 0,9% Wirbeltiere. Der Anteil stark sklerotisierter Insekten war hoch. Die Werte aus Gewölle- und Mageninhalts-Analysen (Literaturangaben) sind prinzipiell vergleichbar. Gewölleanalysen können daher beim Neuntöter mit tolerablem Fehler zur Quantifizierung seiner Nahrung verwendet werden. Von Mai bis August nahm der Anteil der Käfer ab, jener der Hautflügler stetig zu. Die Summe der anderen Arthropodengruppen und die Wirbeltiere konnten in annähernd konstanten Anteilen nachgewiesen werden. Die Abnahme der Käfern ist auf den Rückgang des Anteils koprophiler Arten, insbesondere von Aphodius fossor (Scarabaeidae) zurückzuführen; die Zunahme des Hautflügler-Anteils durch die Abundanzsteigerung der eusozialen Hummeln und Wespen im Verlauf des Sommers zu erklären. Die Minimalbeutegröße des Neuntöters liegt bei etwa 4 mm Körperlänge. Kleinere Beutetiere werden nur bei kummuliertem Auftreten aufgenommen (Ameisen). Der Neuntöter ist ein unspezialisierter Kleintierjäger. Die Optimalbeute ist groß, häufig und dabei leicht zu erjagen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01661128
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  • 3
    Electronic Resource
    Electronic Resource
    Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map more than 130 kb from SOX9 (1996)
    Springer
    Human genetics 〈Berlin〉 97 (1996), S. 186-193 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Campomelic dysplasia (CMPD1) and autosomal XY sex reversal (SRA1) are caused by mutations in the SRY-related gene SOX9 on 17q. Unexpectedly, the 17q breakpoints in four CMPD1 translocation cases previously analyzed by us and others map 50 kb or more from SOX9. Here, we present clinical, cytogenetic, and molecular data from a new CMPD1/SRA1 patient with t(6; 17) (q14; q24). Fluorescence in situ hybridization has shown that the 17q breakpoint in this case maps to the same region as the breakpoints in the other translocation cases, at least 130 kb from SOX9. Likewise, the breakpoints in two of the previously described cases also map more than 130 kb and, as shown by pulsed field gel electrophoresis analysis, at most 400 kb or 690 kb from SOX9. By using a SOX9 coding sequence polymorphism, expression of both SOX9 alleles has been demonstrated by the reverse transcriptase polymerase chain reaction in lymphoblastoid cells from one of the translocation cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02265263
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  • 4
    Electronic Resource
    Electronic Resource
    Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map more than 130 kb from SOX9 (1996)
    Springer
    Human genetics 〈Berlin〉 97 (1996), S. 186-193 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Campomelic dysplasia (CMPD1) and autosomal XY sex reversal (SRA1) are caused by mutations in the SRY-related gene SOX9 on 17q. Unexpectedly, the 17q breakpoints in four CMPD l translocation cases previously analyzed by us and others map 50 kb or more from SOX9. Here, we present clinical, cytogenetic, and molecular data from a new CMPD1/SRA1 patient with t(6; 17) (q14; q24). Fluorescence in situ hybridization has shown that the 17q breakpoint in this case maps to the same region as the breakpoints in the other translocation cases, at least 130 kb from SOX9. Likewise, the breakpoints in two of the previously described cases also map more than 130 kb and, as shown by pulsed field gel electrophoresis analysis, at most 400 kb or 690 kb from SOX9. By using a SOX9 coding sequence polymorphism, expression of both SOX9 alleles has been demonstrated by the reverse transcriptase polymerase chain reaction in lymphoblastoid cells from one of the translocation cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02265263
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  • 5
    Electronic Resource
    Electronic Resource
    Differential in vivo activities of bovine growth hormone analogues (1998)
    Springer
    Transgenic research 7 (1998), S. 61-71 
    Details
    ISSN: 1573-9368
    Keywords: growth hormone ; prolactin ; transgenic mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In rodents, bovine (b) growth hormone (GH) binds only to GH receptors, while human (h) GH binds to both GH and PRL receptors. The phenotypic consequences of expression of bGH and hGH in transgenic mice are different and, in some cases, opposite. In the present study, site-directed in vitro mutagenesis of the bGH gene was used systematically to eliminate its differences from hGH at one, two, three or four sites suspected of conferring lactogenic activity: D11, H18, S57 and T60, respectively (corresponding to sites 12, 19, 57 and 60 of the bGH molecule). The resulting bGH analogues were expressed in cell lines and in transgenic mice. All of the seven bGH analogues produced retained their ability to bind to GH receptors and exhibited somatogenic activity in vitro and in vivo. However, none of them were able to bind to PRL receptors or to elicit detectable lactogenic response in vitro. Transgenic animals expressing any of the generated analogues were characterized by gigantism and splanchnomegaly. The effects of expression of each of the double, triple or quadruple mutants on the seminal vesicle weight resembled the effects of wild-type hGH and differed from the effects of expression of wild-type bGH. There were differences between the effects of the expression of different bGH analogues on plasma PRL levels and on the PRL response to pharmacological blockade of catecholamine synthesis. Plasma LH levels in ovariectomized females were suppressed by several of the analogues tested, an effect not seen in animals expressing wild-type bGH or hGH. Dopamine turnover in the median eminence of male mice was also altered in animals expressing different bGH analogues but not in those expressing wild-type bGH or hGH. In ovariectomized females, the effects of different bGH analogs on the turnover of dopamine and norepine phrine in the median eminence included changes resembling those detected in animals expressing hGH, as well as alterations differing from the effects of bot h bGH and hGH. The results indicate that biological actions of these bGH analogues cannot be characterized simply in terms of enhanced or reduced somatogenic or lactogenic activity and raise a possibility that different sites, domains or features of the tri-dimensional structure of GH are involved in its actions on different cellular targets
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008808106353
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  • 6
    Electronic Resource
    Electronic Resource
    Reefs from space: Satellite imagery, marine ecology, and ethnography in the Dominican Republic (1994)
    Springer
    Human ecology 22 (1994), S. 355-378 
    Details
    ISSN: 1572-9915
    Keywords: remote sensing ; marine ecology ; ethnography ; fisheries ; Dominican Republic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Ethnic Sciences
    Notes: Abstract Coral reef bleaching is an obvious indication that coastal marine ecosystems are being stressed. However, bleached reefs alone are poor indicators because they reflect the final stages of stress. This research project used multidate satellite imagery to look for coral reef changes as indicators of stress. Findings suggest that (1) satellite imagery can be used to identify small-scale changes in coastal marine ecosystems, including coral reefs; (2) remote sensing, marine ecology, and ethnographic data can be integrated to suggest potential causes of coral reef stress; and (3) changes in reef, seagrass, and mangrove ecozones are more closely tied to fishing, tourism, and land use practices than to global warming.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02168857
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  • 7
    Electronic Resource
    Electronic Resource
    Nucleotides. Part LPart IL:[1]. Aglycone protection by the (2-dansylethoxy)carbonyl (= {2-{[5-(dimethylamino)naphthalen-l-yl]sulfonyl}ethoxy}carbonyl; dnseoc) group a new variation in oligodeoxyribonucleotide synthesis (1997)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 80 (1997), S. 200-212 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The (2-dansylethoxy)carbonyl (= {2-{[5-(dimethylamino)naphthalen-l-yl]sulfonyl}ethoxy}carbonyl; dnseoc) group was employed for protection of the amino functions of the aglycone residues. The lactam function of 2′-deoxyguanosine was on the one hand unprotected and on the other hand alkylated at O6 of the aglycone with the 2-(4-nitrophenyl)ethyl (npe) and 2-(phenylsulfonyl)ethyl (pse) group, respectively. The syntheses of monomeric building blocks, both phosphoramidites and nucleoside- functionalized supports, are described for the three common 2′-deoxynucleosides (2′-deoxycytidine, 2′-deoxyadenosine, 2′-deoxyguanosine). As kinetic studies with the tritylated nucleosides showed, the dnseoc group is more labile towards DBU cleavage than the corresponding 2-(4-nitrophenyl)ethyl-(npe) and [2-(4-nitrophenyl)ethoxy]carbonyl(npeoc)-protected analogues (see Table 2). These results were confirmed by the very fast deprotection rate of the dnseoc groups at some oligonucleotides.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19970800118
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  • 8
    Electronic Resource
    Electronic Resource
    Synthesis and characterization of poly[2,3,9,10,16,17,23,24-octakis(dodecyloxycarbonyl)phthalocyaninatogermoxane] (1993)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 194 (1993), S. 493-500 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: In this article we describe the preparation of poly[2,3,9,10,16,17,23,24-octakis(dodecyloxycarbonyl)phthalocyaninatogermoxane] by thermal polycondensation of 2,3,9,10,16,17,23,24-octakis(dodecyloxycarbonyl)phthalocyaninatogermanium dihydroxide, and its characterization. The average molar mass of the resulting polymer was determined. High molar masses are assessible, e.g., M̄w = 360000 g/mol, M̄n = 140000 g/mol, at moderate temperature for the polycondensation (200°C). The polymer shows a liquid-crystalline phase in an extremely large temperature range. Furthermore, Langmuir-Blodgett films (LB films) of the polymer and of the monomer were prepared and characterized. In LB films the phthalocyanine rings are preferentially oriented normal to the dipping direction.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1993.021940212
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  • 9
    Electronic Resource
    Electronic Resource
    Synthesis of high-molecular-weight poly(dimethylsiloxane) of uniform size by anionic polymerization, 1. Initiation by a monofunctional lithium siloxanolate (1992)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 193 (1992), S. 2453-2466 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: An improved procedure for the anionic polymerization of hexamethylcyclotrisiloxane (D3) initiated by a monofunctional lithium derivative is reported. The initiator seeding solution is preferably prepared in benzene, and tetrahydrofuran is used as a cosolvent which makes the presence of additional promoters useless. The main advantage of this procedure is that it delays the appearance of bimodality which is believed to result from a sudden change in aggregate molecularity during the course of the reaction. Applying this method, poly(dimethylsiloxane) samples having a single functional endgroup and possessing high molecular weights and narrow molecular weight distributions (1,03 ≤ M̄w/M̄n ≤ 1,06) were prepared on the 100 g scale.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1992.021930928
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  • 10
    Electronic Resource
    Electronic Resource
    Silylation of poly(vinyl alcohol) with hexamethyldisilazane in liquid ammonia (1995)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 33 (1995), S. 1119-1124 
    Details
    ISSN: 0887-624X
    Keywords: poly(vinyl alcohol) ; silylation ; hexamethyldisilazane ; liquid ammonia ; kinetics ; properties ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Silylation of poly(vinyl alcohol) has been performed with hexamethyldisilazane in liquid ammonia in an autoclave. This novel procedure has the advantage that the educt, the reagent, and the product are soluble in ammonia, which works under homogeneous conditions. No salt like by-products are formed and no tedious purification of the product is necessary. The degree of silylation has been adjusted through the ratio of silylating agent to hydroxy groups. Random incorporation of trimethylsilyl groups was proven by the linear dependence of the glass transition temperature from the degree of silylation and the solubility of the partially silylated material. Quantitative investigation of the silylation reaction showed first-order kinetics for the initial and final stages of the reaction indicative of a reaction where k1 〉 k2 〉 k3. © 1995 John Wiley & Sons, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1995.080330714
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