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  • American Association for the Advancement of Science (AAAS)  (3)
  • 2000-2004  (3)
  • 1
    Publication Date: 2002-01-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Santiago, Mario L -- Rodenburg, Cynthia M -- Kamenya, Shadrack -- Bibollet-Ruche, Frederic -- Gao, Feng -- Bailes, Elizabeth -- Meleth, Sreelatha -- Soong, Seng-Jaw -- Kilby, J Michael -- Moldoveanu, Zina -- Fahey, Babette -- Muller, Martin N -- Ayouba, Ahidjo -- Nerrienet, Eric -- McClure, Harold M -- Heeney, Jonathan L -- Pusey, Anne E -- Collins, D Anthony -- Boesch, Christophe -- Wrangham, Richard W -- Goodall, Jane -- Sharp, Paul M -- Shaw, George M -- Hahn, Beatrice H -- New York, N.Y. -- Science. 2002 Jan 18;295(5554):465.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Alabama at Birmingham, Birmingham, AL 35294-6024, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11799233" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Wild/*virology ; Antibodies, Viral/analysis/urine ; Ape Diseases/*epidemiology ; Cote d'Ivoire/epidemiology ; Feces/virology ; HIV-1/genetics ; Immunoblotting ; Male ; Pan troglodytes/immunology/*virology ; Polymerase Chain Reaction ; Prevalence ; RNA, Viral/analysis ; Simian Acquired Immunodeficiency Syndrome/*epidemiology ; Simian Immunodeficiency Virus/genetics/immunology/*isolation & purification ; Tanzania/epidemiology ; Uganda/epidemiology ; Urine/virology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2004-03-27
    Description: Heterosexual transmission accounts for the majority of human immunodeficiency virus-1 (HIV-1) infections worldwide, yet the viral properties that determine transmission fitness or outgrowth have not been elucidated. Here we show, for eight heterosexual transmission pairs, that recipient viruses were monophyletic, encoding compact, glycan-restricted envelope glycoproteins. These viruses were also uniquely sensitive to neutralization by antibody from the transmitting partner. Thus, the exposure of neutralizing epitopes, which are lost in chronic infection because of immune escape, appears to be favored in the newly infected host. This reveals characteristics of the envelope glycoprotein that influence HIV-1 transmission and may have implications for vaccine design.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Derdeyn, Cynthia A -- Decker, Julie M -- Bibollet-Ruche, Frederic -- Mokili, John L -- Muldoon, Mark -- Denham, Scott A -- Heil, Marintha L -- Kasolo, Francis -- Musonda, Rosemary -- Hahn, Beatrice H -- Shaw, George M -- Korber, Bette T -- Allen, Susan -- Hunter, Eric -- AI-40951/AI/NIAID NIH HHS/ -- AI-51231/AI/NIAID NIH HHS/ -- N01-85338/PHS HHS/ -- U01-AI-41530/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2004 Mar 26;303(5666):2019-22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294 USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15044802" target="_blank"〉PubMed〈/a〉
    Keywords: AIDS Vaccines ; Amino Acid Sequence ; Cohort Studies ; Epitopes/immunology ; Female ; Genes, env ; Glycosylation ; HIV Antibodies/*immunology ; HIV Envelope Protein gp120/chemistry/genetics/*immunology ; HIV Infections/*immunology/*transmission/virology ; HIV-1/genetics/*immunology/physiology ; Heterosexuality ; Humans ; Likelihood Functions ; Male ; Molecular Sequence Data ; Neutralization Tests ; Prospective Studies ; Viral Load ; Zambia
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2003-06-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bailes, Elizabeth -- Gao, Feng -- Bibollet-Ruche, Frederic -- Courgnaud, Valerie -- Peeters, Martine -- Marx, Preston A -- Hahn, Beatrice H -- Sharp, Paul M -- N01 AI85338/AI/NIAID NIH HHS/ -- R01 AI44596/AI/NIAID NIH HHS/ -- R01 AI50529/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2003 Jun 13;300(5626):1713.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Nottingham, Nottingham NG72UH, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12805540" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Ape Diseases/transmission/*virology ; Cercocebus/virology ; Cercopithecinae/*virology ; Cercopithecus/virology ; Genetic Variation ; Likelihood Functions ; Pan troglodytes/classification/physiology/*virology ; Phylogeny ; Predatory Behavior ; Proteome ; *Recombination, Genetic ; Simian Acquired Immunodeficiency Syndrome/transmission/*virology ; Simian Immunodeficiency Virus/classification/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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