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  • Springer  (48)
  • 2000-2004  (28)
  • 1980-1984  (20)
  • 1945-1949
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  • 1
    Electronic Resource
    Electronic Resource
    Effects of Pregnancy and Lactation on Trabecular Bone and Marrow Adipocytes in Rats (2000)
    Springer
    Calcified tissue international 67 (2000), S. 367-372 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Pregnancy — Lactation — Bone histomorphometry — Marrow adipocyte — Bone formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Changes in the structure and metabolism of trabecular bone and marrow adipocytes in rats during pregnancy and the early stage of postpartum were evaluated by investigating bone mineral density (BMD) and bone and fat histomorphometry. Forty-nine female virgin Sprague-Dawley rats aged 200 days were mated and divided into seven groups: (1) beginning controls; (2) antepartum-on-day-7; (3) antepartum-on-day-21; (4) nonlactating on the fourth postpartum day; (5) nonlactating on the sixth postpartum day; (6) nonlactating on the eighth postpartum day; (7) lactating on the eight postpartum day. The significant decreases occurred in the trabecular bone at the end of pregnancy and lactation, and the bone formation increases and the bone structure is almost recovered in nonlactating rats within 6 days of postpartum. The percent adipocyte volume, adipocyte number, and unit adipocyte volume significantly decreased during postpartum whether lactating or nonlactating, and they significantly showed negative correlation with the osteoid volume values. The serum triglyceride value and body weight of the seven groups correlated significantly with the unit adipocyte volume value (r = 0.49, P= 0.004; r = 0.58, P= 0.0005, respectively). We concluded that bone resorption and formation are regulated separately during late pregnancy and lactation and that the recovery of BMD from lactation appears to rely on an acceleration of bone formation. Furthermore, the metabolism of the marrow adipocyte may be correlated with bone formation rates, serum triglyceride value, and body weight during pregnancy and early stage of puerperium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230001145
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  • 2
    Electronic Resource
    Electronic Resource
    Appearance of brush-border antigens and sucrase in the allantoic endoderm cultured in recombination with digestive-tract mesenchymes (1984)
    Springer
    Development genes and evolution 193 (1984), S. 211-218 
    Details
    ISSN: 1432-041X
    Keywords: Allantoic endoderm ; Heterotypic differentiation ; Intestinal epithelium ; Cloacal epithelium ; Immunofluorescence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Allantoic endoderm of 3.5-day chick embryos was cultured in recombination with digestive-tract mesenchymes of 6-day chick embryos, and the differentiation of the endoderm was studied, with special attention being given to the appearance of brush-border (BB) antigens and sucrase. Irrespective of the origin of the associated digestive-tract mesenchymes, the allantoic endoderm differentiated into a columnar epithelium, expressing BB antigens and sucrase, and also into a BB antigen-negative pseudostratified or stratified epithelium of cuboidal or columnar cells with PAS or alcian blue staining in the apical portion or a BB antigen-negative stratified squamous epithelium. These results suggest that 3.5-day allantoic endoderm has the potency to differentiate into intestinal and cloacal epithelium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01260341
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  • 3
    Electronic Resource
    Electronic Resource
    Interleukin-1β Upregulates PTHrP-mRNA Expression and Protein Production and Decreases TGF-β in Normal Human Osteoblast-Like Cells (2000)
    Springer
    Calcified tissue international 66 (2000), S. 363-369 
    Details
    ISSN: 1432-0827
    Keywords: Key words: IL-1β— PTHrP — TGF-β— Human osteoblasts.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Osteoblasts are regulated by complex interactions among systemic hormones, cytokines, and local growth factors. Bone resorption, at the level of the basic multicellular unit, is initiated by stimulation of osteoblast activity. The stimulatory effect of interleukin-1β (IL-1β) on bone resorption has not been fully clarified. We have therefore studied the influence of IL-1β on the local production and secretion of parathyroid hormone-related protein (PTHrP) and transforming growth factor-β (TGF-β) from normal human osteoblast-like cells (hOB cells). Using a quantitative PCR-assay following reverse transcription of RNA, in situ hybridization, and a two-site immunofluorometric assay for PTHrP, we demonstrate that IL-1β in a dose- and time-dependent manner increases PTHrP-mRNA expression and PTHrP-protein secretion. In addition, IL-1β decreased the TGF-β protein concentration in conditioned medium. Our results suggest that the actions of IL-1β on bone may be mediated by novel mechanisms involving both local increase of PTHrP, a potent stimulator of bone resorption, and a decrease of TGF-β, an important anabolic and coupling factor for bone turnover.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230010074
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  • 4
    Electronic Resource
    Electronic Resource
    Cellular localization and metabolic function of n-butylamine-induced amine oxidases in the fungus Aspergillus niger AKU 3302 (2000)
    Springer
    Archives of microbiology 173 (2000), S. 358-365 
    Details
    ISSN: 1432-072X
    Keywords: Amine oxidase Aspergillus niger Localization Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. Using transmission electron microscopy, the amine oxidase activity in Aspergillus niger AKU 3302 was localized to the outer side of the cell wall but not inside the cell using the cerium perhydroxide deposition method. The presence of cerium in the deposit was confirmed by energy-dispersive microanalysis of X-rays. Interestingly, immunocytochemical localization using gold labeling with a specific antibody indicated the presence of amine oxidase protein inside the cell wall and not only on the outer surface. Besides labeling of the cell wall, a high level of labeling was also observed inside the cell in what seemed to be secretory vesicle structures. It is proposed that the highly active amine oxidase AO-I is located in the cell wall and serves primarily as a detoxifying agent, preventing amines from entering and damaging the cell. The amine oxidation exhibits an interesting spatial orientation involving a release of toxic hydrogen peroxide into the extracellular space. The inactive amine oxidase protein located inside the cell is most probably the amine oxidase AO-II, found in cell homogenates. It is also likely that the less active AO-II is an improperly folded precursor of AO-I, which acquired low-level activity after cell homogenization in the presence of Cu(II) and oxygen due to autooxidative formation of topaquinone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002030000154
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  • 5
    Electronic Resource
    Electronic Resource
    A theoretical study on the photoisomerization of thiophene (1983)
    Springer
    Theoretical chemistry accounts 63 (1983), S. 55-68 
    Details
    ISSN: 1432-2234
    Keywords: Photoisomerization ; Thiophene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The photoisomerization of thiophene (3–5 and 2–4 transpositions of carbon atoms) has been studied with ab initio SCF and CI calculations. A possible reaction mechanism from the lowest excited singlet state 1B2 of thiophene can be proposed from potential surface via Dewar thiophene. The 1B2 state of thiophene would easily convert to the biradical intermediate by almost one step. The internal conversion of this species to the S0 state would cause to the transposition of carbon atoms. The effect of phenyl substituent is also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00549155
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  • 6
    Electronic Resource
    Electronic Resource
    Vapour phase growth of vanadium-doped SnO2 needle crystals (1983)
    Springer
    Journal of materials science 2 (1983), S. 741-743 
    Details
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00720547
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  • 7
    Electronic Resource
    Electronic Resource
    Preparation of ferroelectric PZT films by thermal decomposition of organometallic compounds (1984)
    Springer
    Journal of materials science 19 (1984), S. 595-598 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Transparent PZT thin films with perovskite structure were successfully obtained by thermal decomposition of organometallic compounds at the temperatures of 500 to 700° C. The films deposited on platinum substrates were smooth and uniform, but microcrackings were observed in the films deposited on fused silica substrates. The ratio of metal composition in the PZT film agreed with that in the mixture of starting materials. Films obtained at 700° C on platinum substrate showed a hysteresis loop. A spontaneous polarization was 35.65μC cm−2, a saturation remanent polarization was 30.56μC cm−2 and a coercive field was 45 kV cm−1. Dielectric constant and dielectric loss angle were about 300 and 0.05, respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02403247
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  • 8
    Electronic Resource
    Electronic Resource
    Sintering LiTaO3 and KTaO3 with the aid of manganese oxide (1984)
    Springer
    Journal of materials science 19 (1984), S. 1385-1390 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The sintering of LiTaO3 and KTaO3 with the aid of manganese oxide was studied at 1080 to 1300° C by X-ray analysis, scanning electron microscopy (SEM) and X-ray microanalysis (XMA). The sintering of pure LiTaO3 and KTaO3 proceeds concurrently with grain growth, but only achieves a density of 83% at 1300° C and of 72% at 1280° C, respectively. The addition of 3 wt% of MnO2 or Mn3O4 results in rapid densification of LiTaO3 to 90 to 92% within 30 min at 1190° C. In the presence of manganese oxide, KTaO3 densifies to 95% at 1280° C. The action of manganese oxide is attributed to the substitution of Mn3+ for Ta5+ in the LiTaO3 or KTaO3 lattice which enhances the diffusion of the rate-determining species, oxygen, in the oxide. In addition, a liquid phase formed at 1250° C in KTaO3 may significantly contribute to the achievement of 95% densification.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01120051
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  • 9
    Electronic Resource
    Electronic Resource
    Comparative study of grain growth behavior from a supercooled liquid region of Zr65Cu27.5Al7.5 and Zr65Cu35 metallic glasses (2000)
    Springer
    Journal of materials science 35 (2000), S. 3539-3546 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The grain growth behavior of a Zr2Cu crystallinephase from a supercooled liquid region of Zr65Cu27.5Al7.5 and Zr65Cu35 metallic glasses was examined as a function of annealingtime, t a at various temperatures. Since no distinct change ofconstitution and strain in Zr2Cu phase is seen, the grain sizecalculated from a line-broadening of X-ray diffraction peak byScherrer's formula can be used. The calculated grain size is inagreement with that obtained by transmission electron microscopyobservation. The curve of grain size with t a is parabolic. The graingrowth in Zr65Cu35 takes place at lower temperature and its rate isextremely larger as compared with those of Zr65Cu27.5Al7.5. Thesedifferences are originated from the suppression of growth of Zr2Cu byAl atom, which retards the diffusion of Cu owing to the primaryprecipitation of ZrAl in Zr65Cu27.5Al7.5. The formation of ZrAl maybe attributed to the strong chemical affinity between Al and Zr. Theactivation energies for grain growth of 115 kJ mol−1 forZr65Cu27.5Al7.5 and 363 kJ mol−1 for Zr65Cu35 are obtained by theArrhenius plot of grain growth rate against a reciprocal oftemperature. These activation energies reflect the kind and/ormagnitude of diffusion atoms during the grain growth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004805328058
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  • 10
    Electronic Resource
    Electronic Resource
    Grain growth kinetics in a supercooled liquid region of Zr65Cu27.5Al7.5 and Zr65Cu35 metallic glasses (2000)
    Springer
    Journal of materials science 35 (2000), S. 4143-4149 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The grain growth kinetics of a Zr2Cu crystalline phase in a supercooled liquid region of Zr65Cu27.5Al7.5 and Zr65Cu35 metallic glasses was examined at different temperatures. Since no significant changes in the constitution and strain in Zr2Cu phase were seen for the annealed samples, the grain size calculated from a half value width of the X-ray diffraction peak by Scherrer's formula was used. The grain growth is controlled by a single kinetics with a thermal activation process of Arrhenius type, which is described by $$D^3 - D_0^3 = k_0 t_g exp\left( { - \frac{Q}{{RT_a }}} \right).$$ The activation energy for the grain growth of Zr2Cu is 165 ± 10 kJ mol−1 for Zr65Cu27.5Al7.5 and 440 ± 30 kJ mol−1 for Zr65Cu35. The lower activation energy in the ternary glass is attributed to the mechanism of which the crystallization and grain growth are dominated by redistribution of only Al, while the much higher activation energy might reflect the difficulty of the diffusion of Zr with larger atomic size in the binary glass. It is concluded that the difference in the grain growth mechanism is an important factor of stabilizing the glassy state.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004811026610
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