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  • Springer  (97)
  • Wiley-Blackwell  (22)
  • Nature Publishing Group  (5)
  • 2000-2004  (48)
  • 1985-1989  (76)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 53 (2000), S. 732-735 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract  In the estimation of glycosidase activity by dinitrosalicylic acid (DNS) reagent, the stoichiometry of DNS reduction was reported to increase proportionately with the increase in the number of glycosidic linkages present in oligosaccharides liberated by the enzyme. The relationship between increases in DNS reduction and increases in the number of glycosidic bonds was found to be represented by a part of a rectangular hyperbola. The increase was optimum with disaccharide and insignificant when the degree of polymerization (DP) was ≥10. The difference did not arise as a result of the DNSA discriminating between mono- and oligosaccharide oxidation. The relationship stemmed from the acidity of the hydroxyl group adjacent to the reducing group, which repressed DNS reduction. The acidity is likely to decrease with an increase in oligosaccharide chain length. It is suggested that DNS reduction is actually optimum and uniform for all oligosaccharides of DP ≥ 10 and that it is minimum for monosaccharide. Thus the introduction of rectification factors in the estimation of glycosidase activities by the DNS method appears to be justified.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2000-06-13
    Print ISSN: 0175-7598
    Electronic ISSN: 1432-0614
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Springer
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  • 3
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is prevalent in India, where about half of the world's estimated 800,000 cases occur. A role for the genetics of the host in variable susceptibility to leprosy has been indicated by familial clustering, twin studies, complex ...
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature medicine 10 (2004), S. 663-663 
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] To the editor: In their recent article, Ambati and colleagues present important data that provides insight into cell involvement in age-related macular degeneration (AMD). However, they erroneously state that there is “no animal model of drusen deposition or spontaneously occurring CNV ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage. Although the p53 family members p63 and p73 are structurally related to p53, they have not been directly linked to tumour suppression, although they have ...
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  • 6
    ISSN: 1435-1536
    Keywords: Orientation of polymer chains ; mechanical properties ; birefringence ; deformation scheme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The computation of the orientational averages is a great problem in the case of semicrystalline polymers. In a previous communication [1] it has been shown that sinθ=f(λ) sinθ′ describes the orientational changes satisfactorily for a certain class of polymers. In this paper some alternative deformation schemes are also discussed. It has been concluded that birefringence provides a useful guideline in the choice of a deformation scheme.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Photonic network communications 2 (2000), S. 163-184 
    ISSN: 1572-8188
    Keywords: wavelength routed optical network ; dynamic lightpath assignment ; all-optical networks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract In this paper, we have studied a number of algorithms for routing in all-optical wavelength routed networks. We have considered situations where a lightpath is dynamically created in response to a request for communication and the WDM channels constituting the lightpath are reclaimed when the communication is over. We have looked at two schemes for dynamic wavelength allocation. In the first scheme we have assumed the existence of a central agent to maintain a database of existing lightpaths where the central agent attempts to generate a new lightpath in response to a request for communication. In the second scheme, we attempt to generate a new lightpath using a distributed algorithm. In the first scheme we have exploited the existence of multiple paths between any pair of nodes in a network in order to reduce the blocking probability. For the second scheme, we have proposed three distributed strategies to determine, if possible, a lightpath when there is a request for communication. Each of these strategies have their advantages and disadvantages in terms of the expected blocking probability and the set-up time. We have studied the performances of both the schemes using Monte Carlo simulation.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Photonic network communications 2 (2000), S. 185-198 
    ISSN: 1572-8188
    Keywords: all-optical networks (AONs) ; WDM ; lightpath management ; optical layer protocol ; specification ; communicating finite state machine (CFSM) ; validation and reachability analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract In this work, we propose a control protocol for lightpath management in the optical layer of all-optical networks (AONs). AONs follow a layered structure, as used by various network standards, where each layer communicates with its peer through Protocol Data Units (PDUs). In the context of Open System Interconnection (OSI) Reference Model (RM), a new layer, called optical layer, has been introduced in the AON architecture to manage the lightpath related functions. The optical layer lies in between the physical layer and the data link layer. The objective of this paper is to define a specification for an optical layer protocol for managing lightpaths in AONs. In order to study the dynamics of the optical layer protocol system, we first employ the communicating finite state machine model to represent the protocol. Then a reachability analysis of the model is performed to verify the protocol. This paper shows how the optical layer protocol can be specified formally and made error-free by the step-wise refinement of an initial specification, where validation is done after each refinement.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Photonic network communications 2 (2000), S. 369-382 
    ISSN: 1572-8188
    Keywords: all-optical networks ; fault management ; distributed algorithm ; dynamic routing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract This paper presents a distributed algorithm to determine fault avoiding routes between source-destination end-node pairs in an all-optical network. Fault-tolerant routing for WDM routed all-optical networks has not been studied in details in the literature except for using protection switching or loopback recovery. Such schemes use predetermined protection mechanism and hence assume that the protection path is not faulty. This paper considers extensions to a dynamic routing scheme (presented earlier by these authors for fault-free networks) to handle rerouting in case of fault occurrence. The performance degradations of the network because of fault occurrence are then studied in terms of blocking probability and set-up time through simulations.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Lifetime data analysis 6 (2000), S. 281-290 
    ISSN: 1572-9249
    Keywords: contamination model ; optimal tests ; Pivotal Parametric Product ; reliability distributions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Inferences on mixtures of probability distributions, in general,and of life distributions, in particular, are receiving considerableimportance in recent years. The likelihood ratio procedure oftesting for the null hypothesis of no contamination is oftenvery cumbersome and lacks its usual asymptotic properties. Recently,SenGupta (1991) has introduced the notion of an `L-optimal' testfor such testing problems. The idea is to recast the originalseveral parametric hypotheses representation of the null hypothesisin terms of only a single hypothesis involving an appropriatelychosen parametric function. This approach is shown to be bothmathematically elegant and operationally simple for a quite generalclass of mixture distributions which contains, in particular,all mixtures of the one-parameter exponential family and alsoa very rich subclass of mixtures useful in life-testing and reliabilityanalysis. It is also illustrated through two examples—onebased on real-life data and the other on a simulated sample.
    Type of Medium: Electronic Resource
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