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  • Springer  (12)
  • Annual Reviews  (6)
  • American Geophysical Union  (3)
  • 2000-2004  (12)
  • 1985-1989  (9)
  • 1950-1954
  • 1
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Anthropology 31 (2002), S. 69-97 
    ISSN: 0084-6570
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Ethnic Sciences , Biology
    Notes: Abstract Because of their deafness, deaf people have been marked as different and treated problematically by their hearing societies. Until 25 years ago, academic literature addressing deafness typically described deafness as pathology, focusing on cures or mitigation of the perceived handicap. In ethnographic accounts, interactions involving deaf people are sometimes presented as examples of how communities treat atypical members. Recently, studies of deafness have adopted more complex sociocultural perspectives, raising issues of community identity, formation and maintenance, and language ideology. Anthropological researchers have approached the study of d/Deaf communities from at least three useful angles. The first, focusing on the history of these communities, demonstrates that the current issues have roots in the past, including the central role of education in the creation and maintenance of communities. A second approach centers on emic perspectives, drawing on the voices of community members themselves and accounts of ethnographers. A third perspective studies linguistic issues and how particular linguistic issues involving deaf people articulate with those of their hearing societies. To use a cultural definition is not only to assert a new frame of reference, but to consciously reject an older one.... But the cultural definition continues to perplex many. If Deaf people are indeed a cultural group, why then don't they seem more like the Pennan of the island of Borneo, or the Huichol of Mexico? Carol Padden (1996a)
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Neuroscience 11 (1988), S. 61-80 
    ISSN: 0147-006X
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 29 (1989), S. 365-402 
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-5535
    Keywords: Fermentation development ; Cholecystokinin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The natural product asperlicin is the first nonpeptide antagonist of cholecystokinin isolated from a microbial source. At discovery, production of asperlicin by the original soil isolate ofAspergillus alliaceus was between 15 and 30 mg/l. Selection of natural variants ofA. alliaceus, use of Plackett & Burman and Simplex experimental designs; formulation of synthetic media; amino acid supplementation of production media; analysis of complex nitrogen sources for their amino acid content; evaluation of promising media in fermentors; substitution of glycerol for glucose as a carbon source and rational mutant selection all contributed to titer increases to 〉900 mg/l.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0762
    Keywords: Keywords Sex allocation ; Differential mortality ; Rearing conditions ; Brood sex composition ; Lesser black-backed gull ; Larus fuscus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Empirical evidence is growing that the offspring sex ratio in birds can be biased in relation to the body condition of parents during breeding. The sex ratio bias may come about because (1) the actual production of the two sexes may be skewed and/or (2) there may be a sex bias in early nestling mortality contingent on parental condition. By manipulating parental condition and giving them a control brood to rear, thereby eliminating effects operating via the eggs, we examined the extent to which parental condition influences the post-hatching survival of male and female lesser black-backed gulls, Larus fuscus. We found that the pre-fledging survival of male chicks was strongly reduced in all-male broods reared by parents in poor condition. Pre-fledging survival of female chicks was, however, unaffected by parental condition or brood sex composition. Thus, independently of any production biases, sex differences in nestling mortality alone can bias the offspring sex ratio at fledging in relation to the prevailing rearing conditions. In other studies on gulls we have, however, also shown that females in poor condition at laying preferentially produce female eggs. Clearly a bias in fledging sex ratio can occur within the same species due to a combination of differential production and differential post-laying mortality; the latter can involve a differential effect of poor egg quality on male and female offspring, differential effects of brood sex composition on their survival and a difference in the capacity of parents to rear males and females. All of these processes need to be taken into account in attempting to understand offspring sex ratios.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0878
    Keywords: Mammary gland ; Tissue culture ; Collagen gel ; Electron microscopy ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Fragments of human breast epithelium, devoid of all stromal and basal lamina components, which maintain their in vivo topological organisation can be cultured for up to 28 days within a reconstituted rat-tail-derived collagen matrix. These organoids initially undergo a loss of structural and 3-dimensional organisation, typified by loss of lumina formed by epithelial cells, and myosin from myoepithelial cells. Their subsequent reorganisation is dependent on the presence of serum, insulin, hydrocortisone, and cholera toxin in tissue culture medium. After this preliminary phase, a reduction in the concentration of serum, insulin, hydrocortisone, and cholera toxin is necessary to allow the structural differentiation of epithelial and myoepithelial cells. The myoepithelial cells also regain their ability to produce the basal lamina component laminin. The use of bovine-dermal collagen as the matrix, rather than rat-tail-derived collagen is shown to result in more stable organisation and differentiation of the organoids. The successful use of single-cell pellets (derived by trypsinisation of the organoids) in place of organoids in such cultures illustrates that there is no requirement for pre-existing cell/ cell contact or topological organisation of cells prior to embedding within the collagen matrix.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The distribution of γ-aminobutyric acid (GABA) in the human cerebellar cortex was studied using immunohistochemistry for glutamic acid decarboxylase (GAD), the enzyme that catalyses GABA synthesis. Observations by light microscopy revealed, in all layers of the cerebellar cortex, strong, punctate positivity for GAD, related to putative GABAergic nerve terminals, as well as a diffuse cytoplasmic immunoreactivity within neuronal cell bodies. GAD-positive nerve terminals were found in close relationship with the walls of the cerebellar cortex microvessels. Observations by electron microscopy revealed positive nerve terminals in contact with the astrocyte perivascular sheath of capillaries. GAD immunoreactivity was also detected within astroglial perivascular endfeet and endothelial cells. The findings provide further insights into the GABAergic synapses of the circuitry of the human cerebellar cortex. The detection of ‘vascular’ GAD immunoreactivities suggests that GABAergic mechanisms may regulate cerebellar microvessel function.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of science education and technology 9 (2000), S. 311-325 
    ISSN: 1573-1839
    Keywords: Computer simulation ; visualization ; imagery ; conceptual change ; physics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Natural Sciences in General , Technology
    Notes: Abstract Galileo's contemporaries as well as today's students have difficulty understanding relative motion. We hypothesize that the construction of visual models, resolution of these visual models with numeric models, and, in many cases, rejection of commitments such as the belief in one “true” velocity, are necessary for students to form integrated mental models of relative motion events. To investigate students' relative motion problem solving, high school science students were videotaped in classroom and laboratory settings as they performed collaborative predict-observe-explain activities with relative motion computer simulations. Half of the students interacted with simulations that provided animated feedback; the other half received numeric feedback. Learning, as measured by a diagnostic test, occurred following both conditions. There is evidence that many numeric condition students used faulty mechanical algorithms to solve problems, while many animation condition students used mental imagery to solve problems. In this paper, interactions in which student involvement was visual model based will be contrasted with interactions in which involvement was algorithm based. Implications for pedagogy and educational uses of computer simulations will be discussed.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Educational studies in mathematics 42 (2000), S. 179-196 
    ISSN: 1573-0816
    Keywords: language ; mathematics ; secondary ; quadrilaterals ; van Hiele
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract This paper describes an attempt to explore aspects of the language used in children's written work in a secondary mathematics classroom as a means of assessing their mathematical understanding. It focuses on children's conceptualisations of polygons and their attempts to differentiate between them. It also examines the use of database and concordancing software in deepening our understanding of a potentially major source of students' (mis) conceptions: the published materials they engage with. It describes their usefulness in providing a systematic and efficient method of analysis of materials to explore patterns within them. The method is also used to identify possible sources of students' misconceptions about the properties of polygons based on their likely exposure to potentially misleading examples in published materials.
    Type of Medium: Electronic Resource
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  • 10
    Publication Date: 1987-01-01
    Print ISSN: 0302-766X
    Electronic ISSN: 1432-0878
    Topics: Biology , Medicine
    Published by Springer
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