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  • Lepidoptera  (23)
  • healthy volunteers  (17)
  • Biomagnetism (including magnetocardiography)  (16)
  • Springer  (56)
  • 2005-2009
  • 1980-1984  (56)
  • 1965-1969
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  • 1
    Electronic Resource
    Electronic Resource
    The magnetic field produced by the conduction system of the human heart (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 255-265 
    Details
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto È stata sfruttata la risoluzione spaziale del sensore magnetico per fornire stime numeriche del contributo atriale ai campi magnetici registrati esattamente prima della depolarizzazione ventricolare. Si trova che il contributo è piccolo, e questo rafforza l’interpretazione originale secondo la quale questi campi derivano principalmente dal sistema di conduzione del cuore.
    Notes: Summary We have exploited the spatial resolution of the magnetic sensor to provide numerical estimates of the atrial contribution to magnetic fields recorded just prior to ventricular depolarization. The contribution is found to be small, strenghening our original interpretation that such fields originate mostly in the conduction system of the heart.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02455929
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  • 2
    Electronic Resource
    Electronic Resource
    Adaptive noise cancellation in neuromagnetic measurement systems (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 203-213 
    Details
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è studiato lo spettro del rumore di un gradiometro superconduttore a derivata secon da in un agglomerato urbano. I dati sono stati ottenuti dal gradiometro con tre accelerometri ortogonali e un magnetometro a flussometro elettronico triassiale attaccato al dewar. Questi dati sono stati analizzati usando tecniche di elaborazione dei segnali, soprattutto un cancellatore adattativo di rumori, per ridurre i rumori nei dati del gradiometro. I risultati mostrano qui che il rumore dell’esterno e/o il rumore del movimento del dewar possono essere ridotti di 40 dB in potenza di rumore. Si è anche mostrato che, nel caso di basso rapporto segnale-rumore (S/N∼1), può essere estratta un’onda sunusoidale di 10 Hz. Questa tecnica non solo promette riduzione dei rumori, ma ha anche lo scopo d’identificare i segnali di rumore che potrebbero essere veramente considerati parte del responso evocato. L’analisi dei dati che contengono i responsi evocati è ora in corso.
    Notes: Summary The noise spectrum of a superconducting second-derivative gradiometer has been investigated in an urban environment. Data have been acquired from the gradiometer with three orthogonal accelerometers and a triaxial fluxgate magnetometer attached to the dewar. These data have been analyzed by using signal processing techniques, primarily an adaptive noise canceller, to reduce noise in the gradiometer data. Results shown here indicate that the environmental noise and/or the dewar motion noise can be reduced as much as 40 dB in noise power. It is also shown, in the case of poor signal-to-noise ratio (S/N∼1), that a 10 Hz sine wave can be extracted. This technique not only shows promise for noise reduction, but also aids in the identification of noise signals which might be misconstrued as part of the evoked response. Analysis of data containing evoked response is now underway.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02455924
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  • 3
    Electronic Resource
    Electronic Resource
    Neuromagnetic measurements at hospital: Instrumentation and preliminary tests (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 184-194 
    Details
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è costruito espressamente un sistema SQUID in un ospedale di Parigi, che permette indagini neuromagnetiche attinenti con applicazioni cliniche. Un gradiometro simmetrico di second’ordine lavora entro uno schermo per corrente parassite. Ciò è designato ad ottimizzare il costo e l’efficienza del sistema. Le sue prestazioni sono state sperimentate con dati da pazienti e da soggetti normali.
    Notes: Summary A SQUID system was specially built in a Parisian hospital, allowing neuromagnetic investigations dealing with clinical applications. A second-order symmetrical gradiometer works inside an eddy current shield. This was designed for optimizing the cost and the efficiency of the system. Its performances were tested with data from patients and normal subjects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02455922
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  • 4
    Electronic Resource
    Electronic Resource
    Magnetic fields associated with the brain’s response to infrequent events (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 505-511 
    Details
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è studiato il campo magnetico prodotto dal cervello prendendo in considerazione una varietà di eventi rari. Si riporta il carattere temporale della risposta a un raro stimolo uditivo. Il campo magnetico appare offrire un’utile nuova sonda dell’attività endogena nel cervello umano.
    Notes: Summary We have studied the magnetic field produced by the brain when attending to a variety of rare events. The temporal character of the response to a rare auditory stimulus is reported. The magnetic field appears to offer a useful new probe of endogeneous activity in the human brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02455949
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  • 5
    Electronic Resource
    Electronic Resource
    Studies of the different metabolic pathways of antipyrine in man (1982)
    Springer
    European journal of clinical pharmacology 21 (1982), S. 433-441 
    Details
    ISSN: 1432-1041
    Keywords: antipyrine ; antipyrine metabolites ; drug metabolism ; route of administration ; healthy volunteers ; urinary excretion ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of antipyrine in plasma and saliva, and urinary excretion of its major metabolites, were studied following i.v. and oral administration of antipyrine 500 mg to 6 healthy volunteers. Data from both plasma and saliva showed that the oral bioavailability of antipyrine given as an aqueous solution was complete. The saliva/plasma concentration ratio was constant with time from about 3 h onwards, with a mean value of 0.87 after oral and 0.91 after i.v. administration. It is concluded that the pharmacokinetic parameters of antipyrine can be satisfactorily established on the basis of salivary data, although the volume of distribution and clearance values are then slightly too high. After i.v. administration, 3.8±1.9% of the dose was excreted in urine as unchanged antipyrine in 48h, 24.9±6.3% as 4-hydroxyantipyrine, 16.5±3.2% as norantipyrine, 13.0±2.2% as 3-hydroxymethyl-antipyrine and 5.8±1.0% as 3-carboxy-antipyrine. No significant differences were observed following oral administration. The half-lives calculated from the linear part of the urinary excretion rate curves of the metabolites were about the same for oral and i.v. administration, and were of the same order of magnitude as the elimination half-life of parent drug in plasma and saliva. It is important for determination of the ultimate metabolite ratio that urine is collected for at least 36h, because there is a delay in the excretion of 3-hydroxymethyl-antipyrine in urine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00542332
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  • 6
    Electronic Resource
    Electronic Resource
    Influence of alaproclate on antipyrine metabolite formation in man (1984)
    Springer
    European journal of clinical pharmacology 27 (1984), S. 447-452 
    Details
    ISSN: 1432-1041
    Keywords: alaproclate ; antipyrine clearance ; serotonin reuptake inhibitor ; healthy volunteers ; antipyrine metabolism ; metabolite clearance ; alaproclate kinetics ; inhibition of drug metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Alaproclate, a selective serotonin reuptake inhibitor, presently undergoing clinical trial for the treatment of major depressive disorders, has been shown to inhibit hexobarbital metabolism in mice. In the present study the influence of oral alaproclate on the total plasma clearance of antipyrine and on the formation of its metabolites was investigated in 10 healthy volunteers. The peak level of alaproclate was reached after about 1.5 h, and after a distribution phase, its plasma elimination half-life was between 3.0 and 3.5 h. Antipyrine tests were performed before treatment, during the first four doses and after the seventh dose of alaproclate 200 mg/day. During treatment, total plasma antipyrine clearance and the clearance for production of all antipyrine metabolites were reduced by 30%, indicating non-selective inhibition of oxidative drug-metabolizing enzyme activity in man by alaproclate. After the last dose of alaproclate, antipyrine plasma clearance and the clearance to its metabolites returned to control values. In order to allow more detailed evaluation of the results, the time course of the clearances for production of metabolites was investigated. This revealed that the extent of inhibition of metabolite formation by alaproclate was dependent on the plasma alaproclate level, indicating a rapidly reversible inhibition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00549593
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  • 7
    Electronic Resource
    Electronic Resource
    Repellency of pheromones released by females of Heliothis armigera and H. zea to females of both species (1981)
    Springer
    Entomologia experimentalis et applicata 30 (1981), S. 123-127 
    Details
    ISSN: 1570-7458
    Keywords: Sex Pheromones ; Repellent ; Heliothis armigera ; Heliothis zea ; Lepidoptera ; Noctuidae ; cotton bollworm ; corn earworm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé L'examen en olfactomètre a porté sur les réactions face à d'autres femelles de la même espèce, de femelles vierges ou ayant copulé d'Heliothis armigera Hübner et H. zea Boddie. Le lot comprenait 8 femelles, vierges ou ayant copulé en présence d'une femelle vierge ou ayant copulé. Les 4 combinaisons possibles de femelles vierges et de femelles ayant copulé ont été examinées avec 12 répétitions pour chaque espèce. Un extrait de l'extrémité de l'abdomen de femelles vierges d'une espèce a été présenté aux femelles de l'autre espèce pour examiner les possibilités de réactions interspécifiques aux phéromones. Pour chaque espèce, les réactions interspécifiques de répulsion entre femelles ont été hautement significatives par rapport aux témoins, à l'exception toutefois des réactions de femelle ayant copulé face à des femelles ayant elles aussi copulé. Les répulsions moyennes chez H. armigera et H. zea pour les 8 femelles de chaque expérience ont été: a) vierges en présence d'une vierge: 7,33 et 7,66; b) vierges en présence d'une femelles ayant copulé: 5,76 et 5,58; c) femelles ayant copulé en présence d'une vierge: 4,67 et 4,83. Les différences sont hautement significatives entre chaque paire de moyennes et entre chaque paire et le lot témoin; 3,17; 3,17; 3,42; 4,00 pour H. armigera; 3,17; 3,50; 2,83 et 3,75 pour H. zea. Les femelles vierges des deux espèces, H. armigera et H. zea ont présenté une réaction de répulsion en présence d'un extrait de l'abdomen de l'autre espèce; les répulsions moyennes étant respectivement 5,53 et 5,33 contre 3,83 et 3,58 pour le lot trémoin. On peut en conclure que ces répulsions doivent entraîner une tendance à la répartition uniforme.
    Notes: Abstract An olfactometer was used to determine the effect of pheromones released by females of the bollworms Heliothis armigera (Hübner) and H. zea (Boddie) on females of the same species. Four combinations of virgin and mated females were tested for repellency of one to the other. Evidence is presented that females of the two bollworms were repelled by females of the same species. In addition, extracts of virgin female abdomens of each species repelled virgin females of the other species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00300876
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  • 8
    Electronic Resource
    Electronic Resource
    Sex attractant for three species of the genusOncocnemis: O. chandleri (Grt.),O. cibalis (Grt.), andO. mackiei (B. & Benj.) (Lepidoptera: Noctuidae) (1984)
    Springer
    Journal of chemical ecology 10 (1984), S. 1701-1706 
    Details
    ISSN: 1573-1561
    Keywords: Lepidoptera ; Noctuidae ; Oncocnemis chandleri ; Oncocnemis cibalis ; Oncocnemis mackiei ; (5E7Z)-5 ; 7-dodecadienyl acetate ; (Z)-7-dodecenyl acetate ; sex attractant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Oncocnemis chandleri, O. cibalis, andO. mackiei were attracted to chemically baited traps in the field. In all three cases, (5E,7Z)-dodecadienyl acetate was a key component for attraction. Attraction ofO. chandleri to traps baited with the (5E,7Z)-dodecadienyl acetate was inhibited by addition of (Z)-7-dodecenyl acetate.O. cibalis required both (5E,7Z)-dodecadienyl acetate and (Z)-7-dodecenyl acetate for attraction. Electroantennogram responses for the three species are also reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00987356
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  • 9
    Electronic Resource
    Electronic Resource
    High-resolution isofield mapping in magnetocardiography (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 291-300 
    Details
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si presentano i risultati preliminari ottenuti costruendo mediante computer mappe di distribuzione di campo magnetico sulla base di registrazioni ad alta risoluzione effettuate con magnetometro superconduttore. La procedura è stata applicata per esaminare i MCG di 16 pazienti affetti da pregresso infarto del miocardio. Sulla base di questa elaborazione è stato possibile dividere i pazienti in due classi, una delle quali contiene tutti i pazienti con depolarizzazioni tardive.
    Notes: Summary A possible clinical application of a high-resolution magnetic isofield contour mapping technique in cardiography is discussed. Preliminary results are presented in applying this technique to patients with recent myocardial infarction. The patients could be divided into two classes; one of them contains patients with electrical late potentials as a subclass.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02455932
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  • 10
    Electronic Resource
    Electronic Resource
    Diagnostic assessment of human iron stores by measurement of hepatic magnetic susceptibility (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 567-581 
    Details
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è sviluppato un metodo magnetico per misurazioni dirette non invasive del ferro di immagazzinamento epatico umano con uno suscettometro SQUID. Le determinazioni magneticain vivo e chimicain vitro del ferro epatico non eme sono strettamente correlate. Le misurazioni magnetiche dei depositi di ferro sono utili, dal punto di vista clinico, nella diagnosi dei disordini nel metabolismo del ferro.
    Notes: Summary A magnetic method for direct noninvasive measurements of human hepatic storage iron with a SQUID susceptometer has been developed.In vivo magnetic andin vitro chemical determinations of liver nonheme iron are closely correlated. Magnetic measurements of iron stores are clinically useful in the diagnosis of disorders of iron metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02455955
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