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  • Articles  (60)
  • 2005-2009  (36)
  • 1990-1994  (24)
  • Computer Science  (60)
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  • Articles  (60)
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  • 1
    Electronic Resource
    Electronic Resource
    REAL PHYSICS FOR REAL ENGINEERS: RESPONSE TO “PROLEGOMENA TO ANY FUTURE QUALITATIVE PHYSICS” (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Computational intelligence 8 (1992), S. 0 
    Details
    ISSN: 1467-8640
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Computer Science
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-8640.1992.tb00359.x
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  • 2
    Electronic Resource
    Electronic Resource
    Optical character scanning: A discussion of efficiency and politics (1993)
    Springer
    Computers and the humanities 27 (1993), S. 121-127 
    Details
    ISSN: 1572-8412
    Keywords: optical character recognition ; scanning ; off-shore keyboarding ; efficiency ; ARTFL ; cost analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Notes: Abstract Optical Character Recognition is shown to be significantly more expensive than keyboarding, using off-shore contractors, for entry of large amounts of text where high accuracy is required. Using large test samples in French and English, the paper indicates that OCR applications which require significant post-scan editing are labor intensive projects that can be accomplished more efficiently by keyboarding. Most OCR systems are still not capable of entering large amounts of text accurately enough to avoid an expensive editing step.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01830305
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  • 3
    Electronic Resource
    Electronic Resource
    Technical reviews (1992)
    Springer
    Computers and the humanities 26 (1992), S. 157-168 
    Details
    ISSN: 1572-8412
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00116352
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  • 4
    Electronic Resource
    Electronic Resource
    Book reviews (1990)
    Springer
    Computers and the humanities 24 (1990), S. 495-500 
    Details
    ISSN: 1572-8412
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00186493
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  • 5
    Electronic Resource
    Electronic Resource
    Critical theory and textual computing: Comments and suggestions (1993)
    Springer
    Computers and the humanities 27 (1993), S. 395-400 
    Details
    ISSN: 1572-8412
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Notes: Conclusion Donald Bruce and I do speak the same theoretical metalanguage, though I suspect that he is considerably more fluent than I in that tongue. Given the variety of responses, including Bruce's favorable reaction, to my attempts to provoke theoretical debate concerning the nature of electronic text as a new object of research, I am considerably more optimistic than his “knowing smile and tears of rage.” It is my contention that researchers in textual computing have significant advantages in reconceptualizing text precisely because computing technology shatters the evident surface structures of text. If electronic text is a radically different object of research, then theoretical models of the kind discussed in this volume should have a significant impact on disciplines which are currently debating the nature and limits of textuality. I would like to suggest that we, as specialists in textual computing, should make every effort to combine abstract theoretical considerations with clear efforts towards empirical verification. Maintaining that difficult balance between theory, method, and empirical verification is, in my opinion, one of the central contributions that theory of textual computing can make to critical theory in general. The computing environment provides an ideal testing ground for literary theories by encouraging experimentation and verification using real data, an element that is all too often overlooked by many critical theorists.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01829390
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  • 6
    Electronic Resource
    Electronic Resource
    Signs, symbols and discourses: A new direction for computer-aided literature studies (1993)
    Springer
    Computers and the humanities 27 (1993), S. 309-314 
    Details
    ISSN: 1572-8412
    Keywords: computer-aided literature studies ; literature ; literary theory ; structuralism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Notes: Abstract Computer-aided literature studies have failed to have a significant impact on the field as a whole. This failure is traced to a concentration on how a text achieves its literary effect by the examination of subtle semantic or grammatical structures in single texts or the works of individual authors. Computer systems have proven to be very poorly suited to such refined analysis of complex language. Adopting such traditional objects of study has tended to discourage researchers from using the tool to ask questions to which it is better adapted, the examination of large amounts of simple linguistic features. Theoreticians such as Barthes, Foucault and Halliday show the importance of determining the linguistic and semantic characteristics of the language used by the author and her/his audience. Current technology, and databases like the TLG or ARTFL, facilitate such wide-spectrum analyses. Computer-aided methods are thus capable of opening up new areas of study, which can potentially transform the way in which literature is studied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01829380
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  • 7
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    Triassic vertebrates of gondwanan aspect from the richmond basin of virginia (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-08-31
    Description: A new locality of early Late Triassic age in the Richmond basin of east-central Virginia has yielded abundant remains of a diversified assemblage of small to medium-sized tetrapods that closely resembles Southern Hemisphere (Gondwanan) assemblages in the predominance of certain synapsids. Associated palynomorphs indicate an early middle Carnian age for the fossiliferous strata. The discovery suggests that previously recognized differences between tetrapod assemblages of early Late Triassic age from Gondwana and Laurasia at least in part reflect differences in stratigraphic age, rather than geographic separation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sues, H D -- Olsen, P E -- New York, N.Y. -- Science. 1990 Aug 31;249(4972):1020-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17789610" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Secondary structure is the major determinant for interaction of HIV rev protein with RNA (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-02-16
    Description: A region in the human immunodeficiency virus (HIV) env message, with the potential to form a complex secondary structure (designated RRE), interacts with the rev protein (Rev). This interaction is believed to mediate export of HIV structural messenger RNAs from the nucleus to the cytoplasm. In this report the regions essential for Rev interaction with the RRE are further characterized and the functional significance of Rev-RRE interaction in vivo is examined. A single hairpin loop structure within the RRE was found to be a primary determinant for Rev binding in vitro and Rev response in vivo. Maintenance of secondary structure, rather than primary nucleotide sequence alone, appeared to be necessary for Rev-RNA interaction, which distinguishes it from the mechanism for cis-acting elements in DNA. Limited changes within the 200 nucleotides, which preserved the proper RRE conformational structure, were well tolerated for Rev binding and function. Thus, variation among the RRE elements present in the diverse HIV isolates would have little, if any, effect on Rev responsiveness.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Olsen, H S -- Nelbock, P -- Cochrane, A W -- Rosen, C A -- New York, N.Y. -- Science. 1990 Feb 16;247(4944):845-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Oncology and Virology, Roche Institute of Molecular Biology, Nutley, NJ 07110.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2406903" target="_blank"〉PubMed〈/a〉
    Keywords: Base Composition ; Base Sequence ; Chromosome Deletion ; Gene Products, rev/genetics/*metabolism ; Genes, rev ; HIV/*genetics/metabolism ; Molecular Sequence Data ; Mutation ; Nucleic Acid Conformation ; Plasmids ; Protein Conformation ; RNA, Messenger/*genetics/metabolism ; RNA, Viral/genetics/metabolism ; Trans-Activators/*metabolism ; rev Gene Products, Human Immunodeficiency Virus
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Kinetic characterization of ribonuclease-resistant 2'-modified hammerhead ribozymes (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-07-19
    Description: The incorporation of 2'-fluoro- and 2'-aminonucleotides into a hammerhead ribozyme was accomplished by automated chemical synthesis. The presence of 2'-fluorouridines, 2'-fluorocytidines, or 2'-aminouridines did not appreciably decrease catalytic efficiency. Incorporation of 2'-aminocytidines decreased ribozyme activity approximately by a factor of 20. The replacement of all adenosines with 2'-fluoroadenosines abolished catalysis in the presence of MgCl2 within the limits of detection, but some activity was retained in the presence of MnCl2. This effect on catalysis was localized to a specific group of adenines within the conserved single-stranded region of the ribozyme. The decrease in catalytic efficiency was caused by a decrease in the rate constant; the Michaelis constant was unaltered. The 2'-fluoro and 2'-amino modifications conferred resistance toward ribonuclease degradation. Ribozymes containing 2'-fluoro- or 2'-aminonucleotides at all uridine and cytidine positions were stabilized against degradation in rabbit serum by a factor of at least 10(3) compared to unmodified ribozyme.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pieken, W A -- Olsen, D B -- Benseler, F -- Aurup, H -- Eckstein, F -- New York, N.Y. -- Science. 1991 Jul 19;253(5017):314-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max-Planck-Institut fur Experimentelle Medizin, Abteilung Chemie, Gottingen, Federal Republic of Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1857967" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; *Chlorides ; Kinetics ; Magnesium Chloride/pharmacology ; Manganese/pharmacology ; *Manganese Compounds ; Molecular Sequence Data ; Nucleic Acid Conformation ; RNA, Catalytic/chemical synthesis/*metabolism ; Ribonucleases/*metabolism ; Ribonucleotides ; Substrate Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Chaos versus noisy periodicity: alternative hypotheses for childhood epidemics (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-08-03
    Description: Whereas case rates for some childhood diseases (chickenpox) often vary according to an almost regular annual cycle, the incidence of more efficiently transmitted infections such as measles is more variable. Three hypotheses have been proposed to account for such fluctuations. (i) Irregular dynamics result from random shocks to systems with stable equilibria. (ii) The intrinsic dynamics correspond to biennial cycles that are subject to stochastic forcing. (iii) Aperiodic fluctuations are intrinsic to the epidemiology. Comparison of real world data and epidemiological models suggests that measles epidemics are inherently chaotic. Conversely, the extent to which chickenpox outbreaks approximate a yearly cycle depends inversely on the population size.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Olsen, L F -- Schaffer, W M -- New York, N.Y. -- Science. 1990 Aug 3;249(4968):499-504.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry, Odense University, Denmark.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2382131" target="_blank"〉PubMed〈/a〉
    Keywords: Chickenpox/epidemiology ; Child ; *Epidemiology ; Humans ; Measles/epidemiology ; *Models, Biological ; *Models, Statistical ; *Periodicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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