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  • Springer  (46)
  • Wiley  (15)
  • Blackwell Publishing Ltd  (6)
  • Nature Publishing Group
  • 2005-2009  (34)
  • 1995-1999  (31)
  • 1965-1969  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    Sensitivity analysis and optimization of thin laminated structures with a nonsmooth eigenvalue based criterion (1997)
    Springer
    Structural and multidisciplinary optimization 14 (1997), S. 219-224 
    Details
    ISSN: 1615-1488
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This paper presents a discrete model for the design sensitivity analysis of thin laminated angle-ply composite structures using a plate shell element based on a Kirchhoff discrete theory for the bending effects. To overcome the nondifferentiability of multiple eigenvalues, which may occur during a structural optimization involving free vibrations or buckling design situations, a nonsmooth eigenvalue based criterion is implemented. Angle-ply design variables and vectorial distances from the laminated midle surface to the upper surface of each layer are considered as design variables. The design sensitivities and the directional derivatives are evaluated analytically. The efficiency and accuracy of the model developed is discussed with two illustrative cases which show the need to compute sensitivities of multiple eigenvalues as directional derivatives for laminated composite structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01197943
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  • 2
    Electronic Resource
    Electronic Resource
    Shape optimization of axisymmetric shells using a higher-order shear deformation theory (1995)
    Springer
    Structural and multidisciplinary optimization 9 (1995), S. 117-127 
    Details
    ISSN: 1615-1488
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract In this paper structural and sensitivity analysis for the optimization of laminated axisymmetric shells subjected to static constraints and arbitrary loading is presented. The shell thickness, radial coordinate of a nodal point, lamina thickness and the angle of orientation of the fibers are the design variables. The objective of the design optimization is the minimization of the volume of the shell or the strain energy. The model is based on a three-node axisymmetric finite element with 24 degrees of freedom. A higher-order theory is developed for the nonlinear distribution of the meridional displacement component through the thickness of the shell. The sensitivities of the discrete model developed are evaluated analytically using a symbolic manipulator. The efficiency and accuracy of the proposed model is discussed with reference to the applications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01758828
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  • 3
    Electronic Resource
    Electronic Resource
    Mucous cell types in the branchial epithelium of the euryhaline fish Poecilia vivipara (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 49 (1996), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Four types of mucous cells of the branchial epithelium of Poecilia are described. Type I in the apical region of the branchial filament; type II in the apical and interlamellar region; type III cells only in the interlamellar region; and type IV cells in the branchial arch.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.1996.tb00051.x
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  • 4
    Electronic Resource
    Electronic Resource
    Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria (2007)
    [s.l.] : Nature Publishing Group
    Nature medicine 13 (2007), S. 703-710 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Cerebral malaria claims more than 1 million lives per year. We report that heme oxygenase-1 (HO-1, encoded by Hmox1) prevents the development of experimental cerebral malaria (ECM). BALB/c mice infected with Plasmodium berghei ANKA upregulated HO-1 expression and activity and did not develop ECM. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nm1586
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  • 5
    Electronic Resource
    Electronic Resource
    Assessment of the diversity of Paenibacillus species in environmental samples by a novel rpoB-based PCR-DGGE method (2005)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology ecology 53 (2005), S. 0 
    Details
    ISSN: 1574-6941
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: A specific PCR system based on the gene encoding the RNA polymerase beta subunit, rpoB, was developed for amplification and denaturing gradient gel electrophoresis (DGGE) fingerprinting of Paenibacillus communities in environmental samples. This gene has been previously proven to be a powerful identification tool for the discrimination of species within the genus Paenibacillus and could avoid the limitations of 16S rRNA-based phylogenetic analysis. Initially, the PCR system based on universal rpoB primers were used to amplify DNAs of different Paenibacillus species. A new reverse primer (rpoBPAEN) was further designed based on an insertion of six nucleotides in the Paenibacillus sequences analyzed. This semi-nested PCR system was evaluated for specificity using DNAs isolated from 27 Paenibacillus species belonging to different 16S rRNA-based phylogenetic groups and seven non-Paenibacillus species. The non-Paenibacillus species were not amplified using this PCR approach and one group of Paenibacillus species consisting of strains without the six-base insert also were not amplified; these latter strains were found to be distinct based on 16S rRNA gene phylogeny. In addition, a clone library was generated from the rpoB fragments amplified from two Brazilian soil types (Cerrado and Forest) and all 62 clones sequenced were closely related to one of the 22 sequences from Paenibacillus previously obtained in this study. To assess the diversity of Paenibacillus species in Cerrado and Forest soils and in the rhizosphere of different cultivars of maize, a PCR-DGGE system was used. The Paenibacillus DGGE fingerprints showed a clear distinction between communities of Paenibacillus in Forest and Cerrado soils and rhizosphere samples clustered along Cerrado soil. Profiles of cultivars CMS22 and CMS36 clustered together, with only 53% of similarity to CMS11 and CMS04. The results presented here demonstrate the potential use of the rpoB-based Paenibacillus-specific PCR-DGGE method for studying the diversity of Paenibacillus populations in natural environments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsec.2005.01.017
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  • 6
    Electronic Resource
    Electronic Resource
    Physiological responses of Tetrahymena pyriformis to copper, zinc, cycloheximide and Triton X-100 (1999)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology ecology 30 (1999), S. 0 
    Details
    ISSN: 1574-6941
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Protozoa, and particularly ciliates, are essential in aerobic purification processes of wastewaters and have proved to be very sensitive to environmental changes. The physiological response of the ciliate Tetrahymena pyriformis was assessed in terms of mortality, growth and grazing capacity after exposure to four toxicants: copper, zinc, cycloheximide and Triton X-100. In the ranges of concentrations used, mortality, inhibition of growth and inhibition of grazing were observed with all toxicants employed, but in different ways. Copper and zinc showed lower toxicity than observed in other studies with protozoa, though some of the present results are in accordance with those reported by other authors. This supports the importance of the organism tested and the experimental conditions of the bioassays.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6941.1999.tb00649.x
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  • 7
    Electronic Resource
    Electronic Resource
    High levels of nitrifying bacteria in intermittently aerated reactors treating high ammonia wastewater (2005)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology ecology 54 (2005), S. 0 
    Details
    ISSN: 1574-6941
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Changes in the fractions of ammonia-oxidizing bacteria and nitrite-oxidizing bacteria in two laboratory-scale reactors were investigated using 16S rRNA probe hybridizations. The reactors were operated in intermittent aeration mode and different aeration cycles to treat anaerobically digested swine wastewater with ammonia concentrations up to 175 mg NH3-N/L. High ammonia removals (〉98.8%) were achieved even with increased nitrogen loads and lower aeration: non-aeration time ratios of 1 h:3 h. Nitrosomonas/Nitrosococcus mobilis were the dominant ammonia-oxidizing bacteria in the reactors. Nitrospira-like organisms were the dominant nitrite-oxidizing bacteria during most of the investigation, but were occasionally outcompeted by Nitrobacter. High levels of nitrifiers were measured in the biomass of both reactors, and ammonia-oxidizing bacteria and nitrite-oxidizing bacterial levels adjusted to changing aeration: non-aeration time ratios. Theoretical ammonia-oxidizer fractions, determined by a mathematical model, were comparable to the measured values, although the measured biomass fractions were different at each stage while the theoretical values remained approximately constant. Stable ammonia removals and no nitrite accumulation were observed even when rRNA levels of ammonia oxidizers and nitrite-oxidizers reached a minimum of 7.2% and 8.6% of total rRNA, respectively. Stable nitrogen removal performance at an aeration: non-aeration ratio of 1 h:3 h suggests the possibility of significant savings in operational costs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsec.2005.05.001
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of ethanol and acetic acid on the transport of malic acid and glucose in the yeast Schizosaccharomyces pombe: implications in wine deacidification (1995)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 126 (1995), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Ethanol and acetic acid, at concentrations which may occur during wine-making, inhibited the transport of l-malic acid in Schizosaccharomyces pombe. The inhibition was non-competitive, the decrease of the maximum initial velocity following exponential kinetics. Glucose transport was not significantly affected either by ethanol (up to 13%, w/v) or by acetic acid (up to 1.5%, w/v). The uptake of labelled acetic acid followed simple diffusion kinetics, indicating that a carrier was not involved in its transport. Therefore, the undissociated acid appears to be the only form that enters the cells and is probably responsible for the toxic effects. Accordingly, deacidification by Ss. pombe during wine fermentation should take place before, rather than after, the main alcoholic fermentation by Saccharomyces cerevisiae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1995.tb07416.x
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  • 9
    Electronic Resource
    Electronic Resource
    Type III secretion: The bacteria-eukaryotic cell express (2005)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 252 (2005), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Type III secretion (T3S) is an export pathway used by Gram-negative pathogenic bacteria to inject bacterial proteins into the cytosol of eukaryotic host cells. This pathway is characterized by (i) a secretion nanomachine related to the bacterial flagellum, but usually topped by a stiff needle-like structure; (ii) the assembly in the eukaryotic cell membrane of a translocation pore formed by T3S substrates; (iii) a non-cleavable N-terminal secretion signal; (iv) T3S chaperones, assisting the secretion of some substrates; (v) a control mechanism ensuring protein delivery at the right place and time. Here, we review these different aspects focusing in open questions that promise exciting findings in the near future.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsle.2005.08.036
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  • 10
    Electronic Resource
    Electronic Resource
    A simulation model of a high-capacity methane adsorptive storage system (1995)
    Springer
    Adsorption 1 (1995), S. 17-27 
    Details
    ISSN: 1572-8757
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A two-dimensional model is developed to describe the hydrodynamics, heat transfer and adsorption phenomena associated with the adsorptive storage of natural gas (NG) in cylindrical reservoirs. Intraparticle and film resistances to both heat and mass transfer are neglected. In the momentum equation, Ergun's law is considered locally valid and is extended to two dimensions. These assumptions are fully justified in the paper. Numerical results are presented concerning the pressurization and blowdown of an ultra-lightweight 50 litre cylinder, commercially available for the storage of compressed NG, if it were filled with an activated carbon having a good adsorptive storage capacity. A simple formula is also proposed to predict the filling times for fast charges. The predicted temperature changes in the packed-bed are in good agreement with those reported in the literature for an experimental charge/discharge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00704143
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