ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Mutation  (6)
  • 04. Solid Earth::04.06. Seismology::04.06.99. General or miscellaneous  (4)
  • 2005-2009  (7)
  • 2000-2004  (3)
  • 1
    Electronic Resource
    Electronic Resource
    A novel HLA-A*6816 allele possibly generated by a point mutation in a Chilean from Punta Arenas (Magellan Strait) (2000)
    Springer
    Immunogenetics 51 (2000), S. 257-260 
    Details
    ISSN: 1432-1211
    Keywords: Key words Amerindians ; Chileans ; HLA-A*6816 ; Mutation ; Gene conversion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002510050618
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    facet.materialart.
    Unknown
    Strigolactone inhibition of shoot branching (2008)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2008-08-12
    Description: A carotenoid-derived hormonal signal that inhibits shoot branching in plants has long escaped identification. Strigolactones are compounds thought to be derived from carotenoids and are known to trigger the germination of parasitic plant seeds and stimulate symbiotic fungi. Here we present evidence that carotenoid cleavage dioxygenase 8 shoot branching mutants of pea are strigolactone deficient and that strigolactone application restores the wild-type branching phenotype to ccd8 mutants. Moreover, we show that other branching mutants previously characterized as lacking a response to the branching inhibition signal also lack strigolactone response, and are not deficient in strigolactones. These responses are conserved in Arabidopsis. In agreement with the expected properties of the hormonal signal, exogenous strigolactone can be transported in shoots and act at low concentrations. We suggest that endogenous strigolactones or related compounds inhibit shoot branching in plants. Furthermore, ccd8 mutants demonstrate the diverse effects of strigolactones in shoot branching, mycorrhizal symbiosis and parasitic weed interaction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gomez-Roldan, Victoria -- Fermas, Soraya -- Brewer, Philip B -- Puech-Pages, Virginie -- Dun, Elizabeth A -- Pillot, Jean-Paul -- Letisse, Fabien -- Matusova, Radoslava -- Danoun, Saida -- Portais, Jean-Charles -- Bouwmeester, Harro -- Becard, Guillaume -- Beveridge, Christine A -- Rameau, Catherine -- Rochange, Soizic F -- England -- Nature. 2008 Sep 11;455(7210):189-94. doi: 10.1038/nature07271.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Universite de Toulouse, UPS, CNRS, Surface Cellulaire et Signalisation chez les Vegetaux, 24 chemin de Borde Rouge, F-31326 Castanet-Tolosan, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18690209" target="_blank"〉PubMed〈/a〉
    Keywords: Arabidopsis/drug effects/genetics/growth & development ; Arabidopsis Proteins/genetics/metabolism ; Dioxygenases ; Genes, Plant/genetics ; Lactones/analysis/chemistry/*metabolism/pharmacology ; Mutation ; Mycorrhizae/physiology ; Oxygenases/genetics/metabolism ; Peas/drug effects/growth & development/*metabolism/parasitology ; Phenotype ; Plant Growth Regulators/analysis/chemistry/*metabolism/pharmacology ; Plant Proteins/genetics/metabolism ; Plant Roots/drug effects/metabolism ; Plant Shoots/drug effects/*growth & development/*metabolism/parasitology ; Symbiosis ; Terpenes/analysis/chemistry/metabolism/pharmacology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Engineering modified Bt toxins to counter insect resistance (2007)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2007-11-03
    Description: The evolution of insect resistance threatens the effectiveness of Bacillus thuringiensis (Bt) toxins that are widely used in sprays and transgenic crops. Resistance to Bt toxins in some insects is linked with mutations that disrupt a toxin-binding cadherin protein. We show that susceptibility to the Bt toxin Cry1Ab was reduced by cadherin gene silencing with RNA interference in Manduca sexta, confirming cadherin's role in Bt toxicity. Native Cry1A toxins required cadherin to form oligomers, but modified Cry1A toxins lacking one alpha-helix did not. The modified toxins killed cadherin-silenced M. sexta and Bt-resistant Pectinophora gossypiella that had cadherin deletion mutations. Our findings suggest that cadherin promotes Bt toxicity by facilitating toxin oligomerization and demonstrate that the modified Bt toxins may be useful against pests resistant to standard Bt toxins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Soberon, Mario -- Pardo-Lopez, Liliana -- Lopez, Idalia -- Gomez, Isabel -- Tabashnik, Bruce E -- Bravo, Alejandra -- 1R01 AI066014/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2007 Dec 7;318(5856):1640-2. Epub 2007 Nov 1.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Apartado Postal 510-3, Cuernavaca 62250, Morelos, Mexico. mario@ibt.unam.mx〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17975031" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bacterial Proteins/chemistry/*genetics/metabolism/*toxicity ; Bacterial Toxins/chemistry/*genetics/metabolism/*toxicity ; Cadherins/genetics/metabolism ; Endotoxins/chemistry/*genetics/metabolism/*toxicity ; Genetic Engineering ; Hemolysin Proteins/chemistry/*genetics/metabolism/*toxicity ; *Insecticide Resistance ; Larva ; *Manduca/genetics/metabolism ; *Moths/genetics/metabolism ; Mutation ; *Pest Control, Biological ; RNA Interference
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Protection of C. elegans from anoxia by HYL-2 ceramide synthase (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-04-18
    Description: Oxygen deprivation is rapidly deleterious for most organisms. However, Caenorhabditis elegans has developed the ability to survive anoxia for at least 48 hours. Mutations in the DAF-2/DAF-16 insulin-like signaling pathway promote such survival. We describe a pathway involving the HYL-2 ceramide synthase that acts independently of DAF-2. Loss of the ceramide synthase gene hyl-2 results in increased sensitivity of C. elegans to anoxia. C. elegans has two ceramide synthases, hyl-1 and hyl-2, that participate in ceramide biogenesis and affect its ability to survive anoxic conditions. In contrast to hyl-2(lf) mutants, hyl-1(lf) mutants are more resistant to anoxia than normal animals. HYL-1 and HYL-2 have complementary specificities for fatty acyl chains. These data indicate that specific ceramides produced by HYL-2 confer resistance to anoxia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Menuz, Vincent -- Howell, Kate S -- Gentina, Sebastien -- Epstein, Sharon -- Riezman, Isabelle -- Fornallaz-Mulhauser, Monique -- Hengartner, Michael O -- Gomez, Marie -- Riezman, Howard -- Martinou, Jean-Claude -- New York, N.Y. -- Science. 2009 Apr 17;324(5925):381-4. doi: 10.1126/science.1168532.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell Biology, University of Geneva, CH-1211 Geneva 4, Switzerland.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19372430" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apoptosis ; Caenorhabditis elegans/cytology/genetics/*physiology ; Caenorhabditis elegans Proteins/*genetics/*metabolism ; *Cell Hypoxia ; Ceramides/biosynthesis/*physiology ; Gene Deletion ; Genes, Helminth ; Mutation ; Oxidoreductases/*genetics/*metabolism ; Oxygen/*physiology ; Receptor, Insulin/genetics/metabolism ; Saccharomyces cerevisiae/genetics/growth & development/physiology ; Sphingomyelins/biosynthesis/physiology ; Substrate Specificity ; Transformation, Genetic ; Transgenes
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Selective trafficking of non-cell-autonomous proteins mediated by NtNCAPP1 (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-01-18
    Description: In plants, cell-to-cell communication is mediated by plasmodesmata and involves the trafficking of non-cell-autonomous proteins (NCAPs). A component in this pathway, Nicotiana tabacum NON-CELL-AUTONOMOUS PATHWAY PROTEIN1 (NtNCAPP1), was affinity purified and cloned. Protein overlay assays and in vivo studies showed that NtNCAPP1 is located on the endoplasmic reticulum at the cell periphery and displays specificity in its interaction with NCAPs. Deletion of the NtNCAPP1 amino-terminal transmembrane domain produced a dominant-negative mutant that blocked the trafficking of specific NCAPs. Transgenic tobacco plants expressing this mutant form of NtNCAPP1 and plants in which the NtNCAPP1 gene was silenced were compromised in their ability to regulate leaf and floral development. These results support a model in which NCAP delivery to plasmodesmata is both selective and regulated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, Jung-Youn -- Yoo, Byung-Chun -- Rojas, Maria R -- Gomez-Ospina, Natalia -- Staehelin, L Andrew -- Lucas, William J -- GM18639/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2003 Jan 17;299(5605):392-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Section of Plant Biology, Division of Biological Sciences, University of California, 1 Shields Avenue, Davis, CA 95616, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12532017" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Cell Communication ; Cell Line ; Cloning, Molecular ; Cytoplasm/metabolism ; Endoplasmic Reticulum/metabolism ; Flowers/growth & development ; Gene Silencing ; Green Fluorescent Proteins ; Immunohistochemistry ; Luminescent Proteins/metabolism ; Molecular Sequence Data ; Mutation ; Phenotype ; Plant Leaves/growth & development ; Plant Proteins/chemistry/genetics/*isolation & purification/*metabolism ; Plants, Genetically Modified ; Plasmodesmata/*metabolism ; Protein Transport ; Recombinant Fusion Proteins/metabolism ; Tobacco/genetics/growth & development/*metabolism ; Tobacco Mosaic Virus ; Viral Proteins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-07-13
    Description: We describe the efficacy of L-870812, an inhibitor of HIV-1 and SIV integrase, in rhesus macaques infected with the simian-human immunodeficiency virus (SHIV) 89.6P. When initiated before CD4 cell depletion, L-870812 therapy mediated a sustained suppression of viremia, preserving CD4 levels and permitting the induction of virus-specific cellular immunity. L-870812 was also active in chronic infection; however, the magnitude and durability of the effect varied in conjunction with the pretreatment immune response and viral load. These studies demonstrate integrase inhibitor activity in vivo and suggest that cellular immunity facilitates chemotherapeutic efficacy in retroviral infections.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hazuda, Daria J -- Young, Steven D -- Guare, James P -- Anthony, Neville J -- Gomez, Robert P -- Wai, John S -- Vacca, Joseph P -- Handt, Larry -- Motzel, Sherri L -- Klein, Hilton J -- Dornadula, Geethanjali -- Danovich, Robert M -- Witmer, Marc V -- Wilson, Keith A A -- Tussey, Lynda -- Schleif, William A -- Gabryelski, Lori S -- Jin, Lixia -- Miller, Michael D -- Casimiro, Danilo R -- Emini, Emilio A -- Shiver, John W -- New York, N.Y. -- Science. 2004 Jul 23;305(5683):528-32. Epub 2004 Jul 8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Chemistry, Merck Research Laboratories, Post Office Box 4, West Point, PA 19486, USA. daria_hazuda@merck.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15247437" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/*drug therapy/*immunology/virology ; Animals ; Anti-HIV Agents/administration & dosage/blood/pharmacology/therapeutic use ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cells, Cultured ; Drug Resistance, Viral ; HIV Integrase/genetics/metabolism ; HIV Integrase Inhibitors/administration & dosage/blood/pharmacology/therapeutic ; use ; HIV-1/drug effects/enzymology/genetics/*physiology ; Immunity, Cellular ; Integrase Inhibitors/administration & dosage/blood/pharmacology/*therapeutic use ; Integrases/genetics/metabolism ; Leukocytes, Mononuclear/virology ; Macaca mulatta ; Mutation ; Naphthyridines/administration & dosage/blood/pharmacology/*therapeutic use ; Simian Acquired Immunodeficiency Syndrome/*drug therapy/*immunology/virology ; Simian Immunodeficiency Virus/drug effects/enzymology/genetics/*physiology ; Viral Load ; Viremia/drug therapy ; Virus Replication/drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Calibrating the Bakun Wentworth's Method for the Macroseismic Estimation of Earthquake Parameters in Italy (2008)
    Details
    Publication Date: 2017-04-04
    Description: We present the results of a calibration analysis performed on Italian seismicity datasets of the approach proposed by Bakun and Wentworth (1997) to bound earthquakes epicentral area and magnitude from macroseismic data only. The calibration is required as the method derives an intensity magnitude (equal in the mean to moment magnitude Mw) from macroseismic observations by using a regionally suitable attenuation relationship of intensity as a function of Mw and source distance. To this purpose, a training set of earthquakes occurred in Italy since 1980 was selected, for which a large number of intensity observations and reliable instrumental determinations of Mw and epicentral location are available. Following the Bakun-Wentworth’s method, the distribution of intensity data with epicentral distance was analyzed for each one of the events considered and three different functional relations (linear, logarithmic and cubic dependence on distance) were calibrated. We also considered two better constrained (defined on a much larger dataset) intensity attenuation relationships recently proposed for Italy, originally derived as a function of epicentral intensity I0 and, thus, “converted” through an empirical I0-Mw relation. Performance of all the above relationships was then checked both on the training set and on an independent set of recent Italian earthquakes.
    Description: Published
    Description: Hersonissos, Creta island, Greece
    Description: 5.1. TTC - Banche dati e metodi macrosismici
    Description: open
    Keywords: earthquake parameters ; macroseismic ; Bakun and Wentworth method ; macroseismic intensity attenuation relationship ; 04. Solid Earth::04.06. Seismology::04.06.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Abstract
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 8
    facet.materialart.
    Unknown
    The Estimation of Earthquake Parameters in Europe by Using Macroseismic Data: Testing the MEEP Program (2008)
    Details
    Publication Date: 2017-04-04
    Description: In the frame of the NA-4 module of the European project NERIES, a specific task is devoted to the determination of earthquakes parameters from macroseismic data. On this regard, a new methodology, implemented in the program MEEP, has been developed by Musson et al. (see relevant presentation in this session). Here we present and discuss some tests performed by using the MEEP program in order to contribute to the setting up of the code and to validate the methodology itself. To this purpose, a set of earthquakes occurred in different regions of Europe and with different ranges of magnitude have been selected. In particular, the main aspects investigated here are: •reliability of estimates of epicentre location, magnitude and hypocentral depth compared with instrumental determinations; •comparison with epicentral parameters derived by using other methods based on macroseismic data; •sensitivity of the methodology to number and geographic distribution of available intensity data points (IDPs); •sensitivity to the calibration parameters requested by the program. Results of this analysis suggested some modifications of the program
    Description: Published
    Description: Hersonissos, Creta island, Greece
    Description: 5.1. TTC - Banche dati e metodi macrosismici
    Description: open
    Keywords: earthquake parameters ; macroseismic ; 04. Solid Earth::04.06. Seismology::04.06.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Abstract
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 9
    facet.materialart.
    Unknown
    The 2nd Century AD earthquake in Central Italy:a Tentative Parameterization from the Available Archaeosismological Data (2008)
    Details
    Publication Date: 2017-04-04
    Description: The 2nd century AD earthquake in central Italy is only known by an epigraph that mentions restorations at the ancient locality of Pagus Interpromium. The available seismic catalogues report this event with the conventional date of 101 AD, a magnitude Maw of 6.3, and an epicentral location at the village of San Valentino in Abruzzo Citeriore in the province of Pescara. Starting from this sparse information, we gathered all the archaeological data collected during modern excavations at sites which were presumably struck by the earthquake, to improve our knowledge of the damage pattern. The most recent archaeological material found in a collapsed unit is a coin of Antoninus Pius, dated at 147-148 AD. This may represent a post quem date very close to the occurrence of the earthquake. The gathered information has allowed us to roughly delineate an area of possible damage, including the Sulmona Plain and surrounding areas. Comparisons between the possible 2nd century damage distribution and (i) the damage patterns of more recent historical events that have struck the investigated area, (ii) a simulated distribution of intensity, given a certain epicentre (i.e. the Sulmona area) and a related epicentral intensity and (iii) a shaking scenario obtained by assuming the activation of the major active fault of the Sulmona Plain area (the Mt. Morrone fault, Mw 6.6-6.7 based on the fault length), have revealed consistency between the ancient earthquake and the activation of this fault. The comparison between the presumed 2nd century damage and the shaking scenario suggests that also the magnitude mentioned is consistent with the presumed effects of the ancient earthquake. Therefore, we can conclude that: (i) the earthquake occurred shortly after 147-148 AD; (ii) a magnitude Mw 6.6-6.7 can be attributed to it; and (iii) the probable macroseismic epicentral area was Sulmona.
    Description: Published
    Description: Hersonissos, Creta island, Greece
    Description: 3.10. Sismologia storica e archeosismologia
    Description: open
    Keywords: archaeoseismological data ; macroseismic ; earthquake parameters ; 04. Solid Earth::04.06. Seismology::04.06.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Abstract
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 10
    facet.materialart.
    Unknown
    Un Catalogo Sismico Europeo Unificado, NERIES NA4: Progresos en la Peninsula Iberica (2008)
    Details
    Publication Date: 2021-12-15
    Description: Within the European Project NERIES, sponsored by the European Commission in the frame of the Specific Programme "Structuring the European Research Area", the NA4 module is devoted to establish a distributed archive of historical earthquake. NA4 objectives are to establish the required tools leading to the compilation of a comprehensive, digital macroseismic intensity database for the largest European earthquakes (with magnitude 〉=5.8 at least) and a validated and homogeneous European parametric earthquake catalogue for M〉=5, to serve as an authoritative reference for users involved in the assessment of seismic hazard and risk. The main focus is devoted to the time-window before 1900. Some highlights about the whole NA4 project, actual state of the initiatives undertaken in the Iberian Peninsula to contribute to it and future developments are presented.
    Description: Published
    Description: Tomar, Portugal
    Description: 5.1. TTC - Banche dati e metodi macrosismici
    Description: open
    Keywords: earthquake parameters ; macroseismic ; 04. Solid Earth::04.06. Seismology::04.06.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Poster session
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...