Publication Date:
2013-10-27
Description:
Article Immunosequencing enables cost-effective sequencing of repertoires of immune cells, but it often suffers from amplification biases when attempting cell quantification. Here, the authors present a powerful multiplex PCR assay that allows for quantitative and unbiased analysis of frequency of different T cell receptors. Nature Communications doi: 10.1038/ncomms3680 Authors: Christopher S. Carlson, Ryan O. Emerson, Anna M. Sherwood, Cindy Desmarais, Moon-Wook Chung, Joseph M. Parsons, Michelle S. Steen, Marissa A. LaMadrid-Herrmannsfeldt, David W. Williamson, Robert J. Livingston, David Wu, Brent L. Wood, Mark J. Rieder, Harlan Robins
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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