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  • 2010-2014  (58)
  • 1925-1929  (5)
  • 1920-1924  (2)
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  • 1
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    MHD instabilities in accretion mounds - II. 3D simulations (2013)
    Oxford University Press
    Details
    Publication Date: 2013-09-17
    Description: We investigate the onset of pressure-driven toroidal-mode instabilities in accretion mounds on neutron stars by 3D magnetohydrodynamic (MHD) simulations using the pluto MHD code. Our results confirm that for mounds beyond a threshold mass, instabilities form finger-like channels at the periphery, resulting in mass-loss from the magnetically confined mound. Ring-like mounds with hollow interior show the instabilities at the inner edge as well. We perform the simulations for mounds of different sizes to investigate the effect of the mound mass on the growth rate of the instabilities. We also investigate the effect of such instabilities on observables such as cyclotron resonant scattering features and timing properties of such systems.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 2
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    MHD instabilities in accretion mounds - I. 2D axisymmetric simulations (2013)
    Oxford University Press
    Details
    Publication Date: 2013-03-16
    Description: We have performed stability analysis of axisymmetric accretion mounds on neutron stars in high-mass X-ray binaries by 2D magnetohydrodynamic (MHD) simulations with the pluto MHD code. We find that the mounds are stable with respect to interchange instabilities, but the addition of excess mass destabilizes the equilibria. Our simulations confirm that accretion mounds are unstable with respect to MHD instabilities beyond a threshold mass. We investigate both filled and hollow mounds and for the latter also compute the expected profile of cyclotron resonance scattering features (CRSF). In comparison to the CRSF from filled mounds reported in our earlier work, hollow mounds display wider and more complex line profiles.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 3
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    CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization (2012)
    Oxford University Press
    Details
    Publication Date: 2012-12-20
    Description: CTCF is a highly conserved transcriptional regulator protein that performs diverse functions such as regulating gene expression and organizing the 3D structure of the genome. Here, we describe recent updates to a database of CTCF-binding sites, CTCFBSDB ( http://insulatordb.uthsc.edu/ ), which now contains almost 15 million CTCF-binding sequences in 10 species. Since the original publication of the database, studies of the 3D structure of the genome, such as those provided by Hi-C experiments, have suggested that CTCF plays an important role in mediating intra- and inter-chromosomal interactions. To reflect this important progress, we have integrated CTCF-binding sites with genomic topological domains defined using Hi-C data. Additionally, the updated database includes new features enabled by new CTCF-binding site data, including binding site occupancy and the ability to visualize overlapping CTCF-binding sites determined in separate experiments.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 4
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    Bayesian Network Webserver: a comprehensive tool for biological network modeling (2013)
    Oxford University Press
    Details
    Publication Date: 2013-10-19
    Description: : The Bayesian Network Webserver (BNW) is a platform for comprehensive network modeling of systems genetics and other biological datasets. It allows users to quickly and seamlessly upload a dataset, learn the structure of the network model that best explains the data and use the model to understand relationships between network variables. Many datasets, including those used to create genetic network models, contain both discrete (e.g. genotype) and continuous (e.g. gene expression traits) variables, and BNW allows for modeling hybrid datasets. Users of BNW can incorporate prior knowledge during structure learning through an easy-to-use structural constraint interface. After structure learning, users are immediately presented with an interactive network model, which can be used to make testable hypotheses about network relationships. Availability and implementation: BNW, including a downloadable structure learning package, is available at http://compbio.uthsc.edu/BNW . (The BNW interface for adding structural constraints uses HTML5 features that are not supported by current version of Internet Explorer. We suggest using other browsers (e.g. Google Chrome or Mozilla Firefox) when accessing BNW). Contact: ycui2@uthsc.edu Supplementary information: Supplementary data are available at Bioinformatics online.
    Print ISSN: 1367-4803
    Electronic ISSN: 1460-2059
    Topics: Biology , Computer Science , Medicine
    Published by Oxford University Press
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  • 5
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    Single-cell genomics reveals organismal interactions in uncultivated marine protists (2011)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2011-05-10
    Description: Whole-genome shotgun sequence data from three individual cells isolated from seawater, followed by analysis of ribosomal DNA, indicated that the cells represented three divergent clades of picobiliphytes. In contrast with the recent description of this phylum, we found no evidence of plastid DNA nor of nuclear-encoded plastid-targeted proteins, which suggests that these picobiliphytes are heterotrophs. Genome data from one cell were dominated by sequences from a widespread single-stranded DNA virus. This virus was absent from the other two cells, both of which contained non-eukaryote DNA derived from marine Bacteroidetes and large DNA viruses. By using shotgun sequencing of uncultured marine picobiliphytes, we revealed the distinct interactions of individual cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yoon, Hwan Su -- Price, Dana C -- Stepanauskas, Ramunas -- Rajah, Veeran D -- Sieracki, Michael E -- Wilson, William H -- Yang, Eun Chan -- Duffy, Siobain -- Bhattacharya, Debashish -- New York, N.Y. -- Science. 2011 May 6;332(6030):714-7. doi: 10.1126/science.1203163.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Bigelow Laboratory for Ocean Sciences, West Boothbay Harbor, ME 04575, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21551060" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Aquatic Organisms/classification/*genetics/*physiology/virology ; Bacteria/classification/genetics/isolation & purification ; Cell Communication ; Cell Separation ; DNA Viruses/classification/genetics/isolation & purification ; DNA, Bacterial/analysis/genetics ; DNA, Ribosomal/genetics ; DNA, Single-Stranded ; DNA, Viral/analysis/genetics ; Eukaryota/classification/*genetics/*physiology/virology ; *Genome ; Heterotrophic Processes ; Likelihood Functions ; Molecular Sequence Data ; Phylogeny ; Plankton/classification/genetics/physiology/virology ; Plastids/genetics/metabolism ; Proteins/chemistry/genetics ; *Seawater ; Single-Cell Analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Cyanophora paradoxa genome elucidates origin of photosynthesis in algae and plants (2012)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2012-02-22
    Description: The primary endosymbiotic origin of the plastid in eukaryotes more than 1 billion years ago led to the evolution of algae and plants. We analyzed draft genome and transcriptome data from the basally diverging alga Cyanophora paradoxa and provide evidence for a single origin of the primary plastid in the eukaryote supergroup Plantae. C. paradoxa retains ancestral features of starch biosynthesis, fermentation, and plastid protein translocation common to plants and algae but lacks typical eukaryotic light-harvesting complex proteins. Traces of an ancient link to parasites such as Chlamydiae were found in the genomes of C. paradoxa and other Plantae. Apparently, Chlamydia-like bacteria donated genes that allow export of photosynthate from the plastid and its polymerization into storage polysaccharide in the cytosol.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Price, Dana C -- Chan, Cheong Xin -- Yoon, Hwan Su -- Yang, Eun Chan -- Qiu, Huan -- Weber, Andreas P M -- Schwacke, Rainer -- Gross, Jeferson -- Blouin, Nicolas A -- Lane, Chris -- Reyes-Prieto, Adrian -- Durnford, Dion G -- Neilson, Jonathan A D -- Lang, B Franz -- Burger, Gertraud -- Steiner, Jurgen M -- Loffelhardt, Wolfgang -- Meuser, Jonathan E -- Posewitz, Matthew C -- Ball, Steven -- Arias, Maria Cecilia -- Henrissat, Bernard -- Coutinho, Pedro M -- Rensing, Stefan A -- Symeonidi, Aikaterini -- Doddapaneni, Harshavardhan -- Green, Beverley R -- Rajah, Veeran D -- Boore, Jeffrey -- Bhattacharya, Debashish -- MSP-14226/Canadian Institutes of Health Research/Canada -- New York, N.Y. -- Science. 2012 Feb 17;335(6070):843-7. doi: 10.1126/science.1213561.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Ecology, Evolution, and Natural Resources, Rutgers University, New Brunswick, NJ 08901, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22344442" target="_blank"〉PubMed〈/a〉
    Keywords: Biological Evolution ; Cyanobacteria/genetics ; Cyanophora/*genetics ; *Evolution, Molecular ; Gene Transfer, Horizontal ; Genes, Bacterial ; *Genome, Plant ; Molecular Sequence Data ; Photosynthesis/*genetics ; Phylogeny ; Symbiosis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Antimetastatic nanoparticle [Applied Biological Sciences] (2013)
    National Academy of Sciences
    Details
    Publication Date: 2013-04-24
    Description: Although biomedical applications of nanotechnology, which typically involve functionalized nanoparticles, have taken significant strides, biological characterization of unmodified nanoparticles remains underinvestigated. Herein we demonstrate that unmodified gold nanoparticles (AuNPs) inhibit the proliferation of cancer cells in a size- and concentration-dependent manner by abrogating MAPK-signaling. In addition, these AuNPs reverse epithelial-mesenchymal...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 8
    Electronic Resource
    Electronic Resource
    Spermatogenesis of an Indian Scorpion (1924)
    [s.l.] : Nature Publishing Group
    Nature 113 (1924), S. 858-858 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE Spermatogenesis of the Scopionidæ has been of special interest since E. B. Wilson's description of the remarkable behaviour of the mitochondria in Centrurus exilicauda (Wood). In this species the mitochondria of the spermatocyte form a ring, which is divided out among the spermatids in a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/113858a0
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  • 9
    Electronic Resource
    Electronic Resource
    Golgi Body and Vacuome (1929)
    [s.l.] : Nature Publishing Group
    Nature 124 (1929), S. 692-693 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A SMALL piece of ovary of a very young pigeon was kept for about twenty minutes in a trough of dilute solution of neutral red, just pink in colour (strength—1/25000 physiological salt solution). It was then teased out and examined under an oil immersion lens in artificial light. The young ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/124692b0
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  • 10
    Electronic Resource
    Electronic Resource
    On the infiltration of golgi bodies from the follicular epithelium to the egg (1929)
    Springer
    Cell & tissue research 8 (1929), S. 566-577 
    Details
    ISSN: 1432-0878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. In a well advanced oocyte of the tortoise the egg membranes besides the theca and the single-layered epithelium consist of a zona pellucida often differentiated into zona striata and a homogeneous layer; underlying these two layers is a layer of cortical fibrillae or fibrillar layer, Next to this layer, is the limiting membrane of the egg which is not present in all stages and generally disappears in a well developed oocyte. In certain animals either the homogeneous layer or fibrillar layer is absent. 2. In certain animals,Golgi bodies seem to be extruded into the follicle cells from the theca cells. 3. At a particular stage of development the follicle cells become very active and produce a large number of smallGolgi bodies. TheseGolgi granules filter through canalicular passages of the zona radiata into either the homogeneous layer and from thence into the fibrillar layer or where a homogeneous layer is not present directly to the fibrillar layer. Where a fibrillar layer is not present they are transferred directly to the limiting membrane and from thence to the egg. 4. In certain cases e. g. in Fowl, Calotes and Uromastix, fairly large lumps ofGolgi bodies are extruded from the follicle cells through the zona pellucida into the egg. Here the fine canilicular passages do not seem to form a vehicle for the passage of these comparatively larger bodies. 5. The fine canalicular passages in the zona radiata ofTestudo graeca andKachuga smithii and the fibrillar prolongation of the cytoplasm which we have called the fibrillar layer are marked features of the egg membranes at certain stages of development of the egg. During the period when infiltration ofGolgi bodies through these passages takes place slides prepared by silver nitrate and osmic methods show black beaded chains ofGolgi granules in various stages of descent. 6. It is claimed that the extrusion and infiltration ofGolgi bodies from the follicular epithelium to the egg are established phenomena at least in the Vertebrates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587505
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