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  • 2010-2014  (10)
  • 1995-1999  (8)
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  • 1
    Call number: PIK N 073-98-0224
    Type of Medium: Monograph available for loan
    Pages: 322 p.
    ISBN: 1853834076
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 2
    Monograph available for loan
    Monograph available for loan
    White River Junction, Vt : Chelsea Green Publishing
    Call number: PIK P 113-12-0079
    Description / Table of Contents: Contents: Defossilizing fuels -- Transportation : fitter vehicles, smarter use -- Buildings : designs for better living -- Industry : remaking how we make things -- Electricity : repowering prosperity -- Many choices, one future
    Type of Medium: Monograph available for loan
    Pages: XVII, 334 S. : Ill., graph. Darst.
    Edition: 1. print.
    ISBN: 9781603583718
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 3
    Publication Date: 2013-08-31
    Description: The auto industry -- one-seventh of the GNP, and the highest expression of the Iron Age -- is about to trigger the biggest transformation in industrial structure since the microchip. Ultralight cars molded from net-shape advanced composites can be several-fold lighter than present steel cars, yet safer, sportier, and more comfortable, durable, and beautiful. Modern hybrid-electric drives boost efficiency approximately 1.3-1.5x in heavy steel cars, but approximately 5-20x in ultralight, very slippery plafforms. Synergistically combined into ultralight-hybrid 'hypercars,' these elements can yield state-of-the-shelf family cars that average 150-300+ mi/gal -- twice that with state-of-the-art technologies -- yet can also be superior in all other respects, probably including cost: carbon-fiber monocoques can actually be cheaper to mass-produce that steel unibodies. Designing cars more like aircraft and less like tanks requires not only an approximately 400-500 kg curb mass and very low air and road drag, but also an aerospace philosophy of engineering integration. Mass, cost, and complexity turn out to compound with heavy hybrids but to decompound with ultralight hybrids, owing partly to radical simplification. Excellent aerodynamics, preferable including advanced techniques for passive boundary-layer control, will be the key to successful design integration. Transforming automaking is a competitive and environmental imperative, could form the nucleus of a green industrial Renaissance, and would enhance national security by, among other things, saving as much oil as OPEC now extracts. However, this transformation faces serious cultural barriers. For example, hypercars will be more like computers with wheels than like cars with chips -- they'll have an order of magnitude more code than today's cars -- but Detroit is not a software culture. Just the transition from stamped and welded steel to integrated and adhesive-joined synthetics is difficult enough. Nonetheless, hypercars are rapidly heading to market in the late 1990s, because approximately 25 current and intending automakers are eager to capture their potentially decisive competitive advantages -- including order-of-magnitude reductions in product cycle time, tooling cost, assembly effort, and parts count. Hypercars will succeed, and may well sweep the market, not because of mandates or subsidies, but because of manufacturers' quest for competitive advantage and customers' desire for better, smarter cars.
    Keywords: Urban Technology and Transportation
    Type: Transportation Beyond 2000: Technologies Needed for Engineering Design; 155-182; NASA-CP-10184-Pt-1
    Format: application/pdf
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  • 4
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    Barcelona : Galaxia Gutenberg | Wuppertal : Wuppertal Institut für Klima, Umwelt, Energie
    Publication Date: 2018-11-19
    Keywords: ddc:600
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: Spanish
    Type: book , doc-type:book
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  • 5
    Publication Date: 2014-08-15
    Keywords: ddc:330
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
    Type: contributiontoperiodical , doc-type:contributionToPeriodical
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  • 6
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    London : Earthscan | Wuppertal : Wuppertal Institut für Klima, Umwelt, Energie
    Publication Date: 2018-11-19
    Keywords: ddc:600
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: English
    Type: book , doc-type:book
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  • 7
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    München : Droemer Knaur | Wuppertal : Wuppertal Institut für Klima, Umwelt, Energie
    Publication Date: 2018-11-19
    Description: Die Botschaft von Faktor Vier ist neu, einfach und aufregend: neu, weil sie nichts Geringeres ankündigt als eine neue Richtung des technischen Fortschritts, einfach, weil sie dafür eine einfache Formel anbietet, und aufregend, weil sie Profite verspricht. Es geht darum, weniger Natur zu verbrauchen und mit dem Wenigen wirksamer zu arbieten. Wir müssen eine Effizienzrevolution in Gang setzen, die dazu führt, daß wir trotz halbierter Naturnutzung den verteilbaren Wohlstand verdoppeln können.
    Keywords: ddc:600
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
    Type: book , doc-type:book
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  • 8
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-09-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lovins, A B -- New York, N.Y. -- Science. 1999 Sep 3;285(5433):1489-91; author reply 1492.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10498532" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture/*methods ; Crops, Agricultural/*genetics ; Directed Molecular Evolution ; *Food ; *Plants, Genetically Modified ; United States ; United States Department of Agriculture ; United States Environmental Protection Agency ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2014-01-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Costanza, Robert -- Kubiszewski, Ida -- Giovannini, Enrico -- Lovins, Hunter -- McGlade, Jacqueline -- Pickett, Kate E -- Ragnarsdottir, Kristin Vala -- Roberts, Debra -- De Vogli, Roberto -- Wilkinson, Richard -- England -- Nature. 2014 Jan 16;505(7483):283-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24436983" target="_blank"〉PubMed〈/a〉
    Keywords: Conservation of Natural Resources/statistics & numerical data ; Environment ; Gross Domestic Product/statistics & numerical data/*trends ; Humans ; Life Expectancy ; Personal Satisfaction ; *Quality of Life ; Socioeconomic Factors ; Sociology/*methods
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2013-05-22
    Description: Background: Ciliary neurotrophic factor (CNTF) expression is repressed in astrocytes by neuronal contact in the CNS and is rapidly induced by injury. Here, we defined an inhibitory integrin signaling pathway. Results: The integrin substrates laminin, fibronectin and vitronectin, but not collagen, thrombospondin or fibrinogen, reduced CNTF expression in C6 astroglioma cells. Antibodies against alphav and beta5, but not alpha6 or beta1, integrin induced CNTF. Together, the ligand and antibody specificity suggests that CNTF is repressed by alphavbeta5 integrin. Antibodies against Thy1, an abundant neuronal surface protein whose function is unclear, induced CNTF in neuron-astrocyte co-cultures indicating that it is a neuroglial CNTF repressor. Inhibition of the integrin signaling molecule Focal Adhesion Kinase (FAK) or the downstream c-Jun N-terminal kinase (JNK), but not extracellular regulated kinase (ERK) or p38 MAPK, greatly induced CNTF mRNA and protein expression within 4 hours. This selective inhibitory pathway phosphorylated STAT3 on its inhibitory ser-727 residue interfering with activity of the pro-transcription Tyr-705 residue. STAT3 can activate CNTF transcription because it bound to its promoter and FAK antagonist-induced CNTF was reduced by blocking STAT3. Microinjection of FAK inhibitor directly into the brain or spinal cord in adult mice rapidly induced CNTF mRNA and protein expression. Importantly, systemic treatment with FAK inhibitors over 3 days induced CNTF in the subventricular zone and increased neurogenesis. Conclusions: Neuron-astroglia contact mediated by integrins serves as a sensor to enable rapid neurotrophic responses and provides a new pharmacological avenue to exploit the neuroprotective properties of endogenous CNTF.
    Electronic ISSN: 1478-811X
    Topics: Biology , Medicine
    Published by BioMed Central
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