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  • Springer  (294)
  • Wiley  (23)
  • National Academy of Sciences  (9)
  • Nature Publishing Group  (3)
  • Taylor & Francis
  • 2015-2019  (308)
  • 1980-1984  (14)
  • 1975-1979  (9)
  • 1
    Electronic Resource
    Electronic Resource
    A novel intercistronic regulatory element of prokaryotic operons (1982)
    [s.l.] : Nature Publishing Group
    Nature 298 (1982), S. 760-762 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The histidine transport operon of S. typhimurium consists of four cistrons, coordinately transcribed from a single promoter (see accompanying letter4). Between the first two genes of this operon, hisJ (encoding the periplasmic histidine-binding protein) and hisO (encoding a membrane-bound protein), ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/298760a0
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  • 2
    Electronic Resource
    Electronic Resource
    Plant molecular biology comes of age (1979)
    [s.l.] : Nature Publishing Group
    Nature 280 (1979), S. 719-720 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] PLANT molecular biology is rapidly coming of age, or at least such was the consensus of 160 plant scientists from several dozen countries who attented a recent workshop on Genome Organisation and Expression in Plants. The workshop underscored the number of highly qualified young investigators now ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/280719a0
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of seed size on seedling size in Virola surinamensis; a within and between tree analysis (1982)
    Springer
    Oecologia 53 (1982), S. 347-351 
    Details
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We conducted a greenhouse study of the effects of initial seed mass on seedling characteristics in a Panamanian population of Virola surinamensis, a canopy tree in which mean seed mass of different individuals ranges from 1.34 to 4.04g. The system is of particular interest because birds preferentially eat fruits of small-seeded plants, leaving seedlings of large-seeded individuals under conditions of potentially severe sibling competition (Howe and Vande Kerckhove 1980). Effects of differences of mean seed mass between trees are explored using an analysis of variance, while effects of seed-mass variation within crops are demonstrated with a regression analysis. A two-way analysis of variance decisively shows effects of parental source and light condition on seedling height, leaf length, and dry shoot mass (all P〈0.0001). A posteriori tests show that differences in seedling characteristics reflect differences in initial seed mass, with especially strong differences apparent in shoot mass. Regression of seedling characteristics on initial seed mass shows that variation of seed size within a crop is sufficient to influence shoot mass at 15 weeks (P〈0.0001). Effects of size differences of seeds that land adjacent to each other, either under the parent or in monkey droppings, are documented with growth of pairs of seedlings in pots. Differences in shoot height and mass at 15 weeks are evident when seeds of average size differ by only 0.2 g, and dramatic differences are evident when paired seeds differ by an average of 1.5 g. Seedlings grow more when isolated than when planted with conspecifics. These experimental results offer indirect support for the hypothesis that small-seeded Virola parents secure an advantage in reproduction through differential dispersal, while large-seeded plants produce more competitive seedlings under their own crowns — an advantage most likely to be of importance when frugivores are scarce.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00389011
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  • 4
    Electronic Resource
    Electronic Resource
    Genetic kin recognition: honey bees discriminate between full and half sisters (1983)
    [s.l.] : Nature Publishing Group
    Nature 302 (1983), S. 147-148 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Queen honey bees mate with a number of different drones before they lay their first eggs11. The sperm, to some extent, mix in the spermatheca and the hive contains several distinct patrilineal worker groups of full sisters while the workers are matrilineal half sisters across groups12'13. In ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/302147a0
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  • 5
    Electronic Resource
    Electronic Resource
    Kin structure and the swarming behavior of the honey bee Apis mellifera (1982)
    Springer
    Behavioral ecology and sociobiology 10 (1982), S. 265-270 
    Details
    ISSN: 1432-0762
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Experimental hives obtained from cordovan queens that were instrumentally inseminated with semen from one cordovan and one Italian drone were set up and allowed to swarm. Cordovan provides a resessive genetic marker system (cuticle color) so that the workers from the cordovan and Italian male lines are distinguishable. Our results show that these patrilineal worker groups segregate non-randomly during colony fission and this segregation cannot be explained by observed age structure. Evidence of innate kin recognition in bees has been previously established. We argue that kin recognition could be responsible for the observed non-random grouping of kin during swarming.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00302815
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  • 6
    Electronic Resource
    Electronic Resource
    Solutions of several 3He-A textures bearing surface singularities (1978)
    Springer
    Journal of low temperature physics 32 (1978), S. 301-321 
    Details
    ISSN: 1573-7357
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Exact solutions are found of three textures for superfluid helium-3 in the A phase: two cylindrically symmetric textures in half-spaces each bearing a point singularity on the surface (which are categorized as the circular and hyperbolic boojum textures by Mermin), and a vortex sheet texture in a slab geometry, which is singular on two straight lines, one on each wall. The dipole interaction between the spin axis % MathType!MTEF!2!1!+-% feaafeart1ev1aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn% hiov2DGi1BTfMBaeXatLxBI9gBaerbd9wDYLwzYbItLDharqqtubsr% 4rNCHbGeaGqiVu0Je9sqqrpepC0xbbL8F4rqaqpepeea0xe9qqVa0l% b9peea0lb9sq-JfrVkFHe9peea0dXdarVe0Fb9pgea0xa9pue9Fve9% Ffc8meGabaqaciGacaGaaeqabaWaaeaaeaaakeaaieqaceWFKbGbaK% aaaaa!387B!\[{\hat d}\] and the orbital axis Î is taken into account to leading order by letting % MathType!MTEF!2!1!+-% feaafeart1ev1aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn% hiov2DGi1BTfMBaeXatLxBI9gBaerbd9wDYLwzYbItLDharqqtubsr% 4rNCHbGeaGqiVu0Je9sqqrpepC0xbbL8F4rqaqpepeea0xe9qqVa0l% b9peea0lb9sq-JfrVkFHe9peea0dXdarVe0Fb9pgea0xa9pue9Fve9% Ffc8meGabaqaciGacaGaaeqabaWaaeaaeaaakeaaieqaceWFKbGbaK% aaaaa!387B!\[{\hat d}\] = Î, assuming temperature T is near the transition temperature T c, and the container size is ≫10\s-3 cm (the dipole characteristic length). Guided by these exact solutions, we then construct an approximate solution for a coreless vortex texture, which was first introduced by Anderson and Toulouse and later modified by Mermin in order for it to fit between two parallel surfaces. It was proposed by Anderson and Toulouse that such coreless vortex textures should replace usual vortex lines in mediating the decay of superfluidity and in transferring angular momentum from the container wall to the superfluid 3He-A. This is found to be true here only if D158.0(ξR)1/2, where D is the thickness of the slab geometry assumed R is the lateral size of this geometry, and ξ is the core size of a usual vortex line in 3He-A. This analysis is good for R ≫ D, but it should remain semiquantitatively valid down to R ~(2—3)D.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00116917
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  • 7
    Electronic Resource
    Electronic Resource
    Isolation and restriction mapping of plasmids containing ribosomal DNA sequences from the rrn B cistron of E. coli (1979)
    Springer
    Molecular genetics and genomics 172 (1979), S. 171-178 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Recombinant plasmids containing the entire 16S RNA gene from the rrn B cistron of E. coli inserted in Col E1 and pBR322 plasmid vectors have been constructed. These plasmids have been mapped using several restriction endonucleases as well as by DNA-RNA hybridization. These maps reveal previously undetected restriction sites in the rrn B cistron and in Col E1 plasmid DNA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00268279
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  • 8
    Electronic Resource
    Electronic Resource
    Composition and abundance of phytoplankton in tributaries of the lower Colorado river, Grand Canyon region (1979)
    Springer
    Hydrobiologia 66 (1979), S. 81-93 
    Details
    ISSN: 1573-5117
    Keywords: algae ; phytoplankton ; Colorado River ; Grand Canyon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Phytoplankton distribution and abundance in eleven tributaries of the Colorado River within the Grand Canyon were investigated from April, 1975 to June, 1976. During this period a total of 56 genera and 156 species of phytoplankton was identified. Phytoplankton species of the individual tributaries were quite distinct, with only four diatom species, Diatoma vulgare, Navicula tripunctata, Nitzschia linearis and Synedra ulna, common to all the tributaries. Bright Angel Creek, Shinumo Creek and Elves Chasm were the tributaries with the most diverse algal flora, whereas Vaseys Paradise, Tapeats Creek, Deer Creek and Havasu Creek showed the lowest species richness. Elves Chasm and Diamond Creek had the highest phytoplankton numbers. Phytoplankton abundance and species richness appeared to be influenced by high turbidity, current velocity, fluctuating water levels and age of the water. Some of the dominant algal species, Biddulphia laevis, Cocconeis pediculus, Cymbella ventricosa, Epithemia sorex, Gomphonema parvulum and Synedra ulna, showed significant correlations with specific physico-chemical characteristics of the tributaries.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00019143
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  • 9
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    Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation (2019)
    National Academy of Sciences
    Details
    Publication Date: 2019-10-01
    Description: Costimulation is required for optimal T cell activation, yet it is unclear whether poxviruses dedicatedly subvert costimulation during infection. Here, we report that the secreted M2 protein encoded by cowpox virus (CPXV) specifically interacts with human and murine B7.1 (CD80) and B7.2 (CD86). We also show that M2 competes with CD28 and CTLA4 for binding to cell surface B7 ligands, with stronger efficacy against CD28. Functionally, recombinant M2 and culture supernatants from wild-type (WT) but not M2-deficient (∆M2) CPXV-infected cells can potently suppress B7 ligand-mediated T cell proliferation and interleukin-2 (IL-2) production. Furthermore, we observed increased antiviral CD4 and CD8 T cell responses in C57BL/6 mice challenged by ∆M2 CPXV compared with WT virus. These differences in immune responses to ∆M2 and WT CPXV were not observed in CD28-deficient mice. Taken together, our findings define a mechanism of viral sabotage of T cell activation that highlights the role of CD28 costimulation in host defense against poxvirus infections.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 10
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    PTEN regulates natural killer cell trafficking in vivo (2015)
    National Academy of Sciences
    Details
    Publication Date: 2015-02-02
    Description: Phosphatase and tensin homolog (PTEN) is a critical negative regulator of the phosphoinositide-3 kinase pathway, members of which play integral roles in natural killer (NK) cell development and function. However, the functions of PTEN in NK cell biology remain unknown. Here, we used an NK cell-specific PTEN-deletion mouse model to define the ramifications of intrinsic NK cell PTEN loss in vivo. In these mice, there was a significant defect in NK cell numbers in the bone marrow and peripheral organs despite increased proliferation and intact peripheral NK cell maturation. Unexpectedly, we observed a significant expansion of peripheral blood NK cells and the premature egress of NK cells from the bone marrow. The altered trafficking of NK cells from peripheral organs into the blood was due to selective hyperresponsiveness to the blood localizing chemokine S1P. To address the importance of this trafficking defect to NK cell immune responses, we investigated the ability of PTEN-deficient NK cells to traffic to a site of tumor challenge. PTEN-deficient NK cells were defective at migrating to distal tumor sites but were more effective at clearing tumors actively introduced into the peripheral blood. Collectively, these data identify PTEN as an essential regulator of NK cell localization in vivo during both homeostasis and malignancy.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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