Publication Date:
2015-05-14
Description:
Article FMNL formins polymerize actin filaments to generate cellular protrusions such as lamellipodia and filopodia at the leading edge of a cell. Here the authors provide detailed mechanistic insights into the formation of actin-based protrusions through GTPase dependent activation and membrane localization of FMNL1 and FMNL2. Nature Communications doi: 10.1038/ncomms8088 Authors: Sonja Kühn, Constanze Erdmann, Frieda Kage, Jennifer Block, Lisa Schwenkmezger, Anika Steffen, Klemens Rottner, Matthias Geyer
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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