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  • Springer  (53)
  • Institute of Physics  (30)
  • Emerald
  • 2015-2019  (40)
  • 1995-1999  (36)
  • 1985-1989  (10)
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  • 1
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    The @TQM magazine 10 (1998), S. 458-463 
    ISSN: 0954-478X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Regarding preventive quality management, Germany was lagging behind for many years. Managers relied on the famous mark "Made in Germany" for too long. They did not realize that international competition had tightened. However, times have changed. Starting with the boom in ISO certifications, Germany is getting back on track again. Today, total quality management and business excellence concepts are gaining ground. Positive trends regarding both applications for Germany's Ludwig-Erhard-Preis and the use of self-assessment show that the quality movement has got a new impetus.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    The @TQM magazine 9 (1997), S. 217-220 
    ISSN: 0954-478X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Notes the importance of countries beyond Europe in terms of the contribution of valuable ideas to the development of TQM. Looks at the introduction of the Australian Quality Award and its development from 1988 to the present day. Examines in detail the criteria and purpose of the award.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    International journal of quality science 3 (1998), S. 147-170 
    ISSN: 1359-8538
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Self-assessment based on TQM criteria frameworks has become a widespread management tool. Apart from the Malcolm Baldrige National Quality Award in the USA, the European Model for Business Excellence has become the most important framework of this kind for Europe. This article first reflects on how self-assessment basically fits into a total quality management context. It will be shown, that an integration with corporate planning is inevitable to guarantee the success of self-assessment in the long run. Most emphasis is placed on different approaches to self-assessment in a combination of case study evidence and literature review. The approaches include the assessment model of the European Foundation for Quality Management, a workshop approach, a pro forma approach and the so-called peer involvement approach to self-assessment. The presentation of these approaches is enhanced by the personal experiences of the authors from some 40 self-assessments they have coached.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular modeling 3 (1997), S. 338-346 
    ISSN: 0948-5023
    Keywords: Keywords: Free-Wilson-analysis ; PLS ; genetic algorithm ; CoMFA ; piritrexim analogous
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Quantitative structure-activity relationships for piritrexim and analogues acting as inhibitors of tumour cell growth have been derived. First the Free-Wilson-method was used on a homologous training set of eight derivatives. The selection of variables important for the biological activity of the compounds was carried out with different multivariate methods as multiple linear regression, the partial least squares method und a genetic algorithm. The derivation of three-dimensional structure activity relationships started with a systematic conformational analysis of all compounds. For the conformations having minimal energy and being in agreement with the crystal structure of piritrexim charges were calculated with the AM1 hamiltonian. For the superimposition of the derivatives two methods were used: maximal similarity of the common substructure or of the molecular fields. A Comparative Molecular Field Analysis with steric and electrostastic fields identified regions important for the activity of the studied compounds independent of the chosen alignment and also correctly predicted the activity of two nonhomologous compounds.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    JETP letters 63 (1996), S. 43-49 
    ISSN: 1090-6487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Slight changes with temperature in the director orientation at the surface of a perfect planar cholesteric liquid crystal (CLC) layer, which are precursors of a jump in the pitch of the cholesteric helix, are observed by measuring the temperature dependence of the optical transmission spectra of the layer. The observed changes in the director orientation are described in the framework of the continuum theory of CLCs, supplemented with allowance for the surface anchoring forces. In particular, the angle of deviation of the director at the surface from the alignment direction at the exact temperature of the jump in pitch is expressed in terms of the anchoring potential. The relation obtained is use to find the anchoring potential in the samples.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of experimental and theoretical physics 85 (1997), S. 285-291 
    ISSN: 1090-6509
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Hysteresis of the temperature of jumps in the cholesteric pitch in planar layers of cholesteric liquid crystals (CLCs) has been observed in the temperature dependence of the optical transmission spectra measured in a 4.8 ¼m thick specimen of a 60% chiral racemic mixture of CE6. The temperature difference for the pitch jumps during heating and cooling was equal to about 0.1°C near 40.3°C. No difference in the temperature of the pitch jumps during heating and cooling was observed for an 18 µm thick specimen. A theoretical description of this hysteresis is presented on the basis of a continuum theory of elasticity of CLCs that also takes account of the surface anchoring of the CLC. Different possible mechanisms leading to a change in the director configuration in the layer during a pitch jump and their correspondence to the jump mechanism and hysteresis which occur in the experimental specimens are discussed.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A new approach is presented which allows the in vivo visualization of individual chromosome territories in the nuclei of living human cells. The fluorescent thymidine analog Cy3-AP3-dUTP was microinjected into the nuclei of cultured human cells, such as human diploid fibroblasts, HeLa cells and neuroblastoma cells. The fluorescent analog was incorporated during S-phase into the replicating genomic DNA. Labelled cells were further cultivated for several cell cycles in normal medium. This well-known scheme yielded sister chromatid labelling. Random segregation of labelled and unlabelled chromatids into daughter nuclei resulted in nuclei exhibiting individual in vivo detectable chromatid territories. The territories were composed of subcompartments with diameters ranging between approximately 400 and 800 nm which we refer to as subchromosomal foci. Time-resolved in vivo studies demonstrated changes of positioning and shape of territories and subchromosomal foci. The hypothesis that subchromosomal foci persist as functionally distinct entities was supported by double labelling of chromatin with CldU and IdU, respectively, at early and late S-phase and subsequent cultivation of corresponding cells for 5–10 cell cycles before fixation and immunocytochemical detection. This scheme yielded segregated chromatid territories with distinctly separated subchromosomal foci composed of either early- or late-replicating chromatin. The size range of subchromosomal foci was similar after shorter (2 h) and longer (16 h) labelling periods and was observed in nuclei of both living and fixed cells, suggesting their structural identity. A possible functional relevance of chromosome territory compartmentalization into subchromosomal foci is discussed in the context of present models of interphase chromosome and nuclear architecture.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 59 (1988), S. 257-263 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract The utility of the back-propagation method in establishing suitable weights in a distributed adaptive network has been demonstrated repeatedly. Unfortunately, in many applications, the number of iterations required before convergence can be large. Modifications to the back-propagation algorithm described by Rumelhart et al. (1986) can greatly accelerate convergence. The modifications consist of three changes:1) instead of updating the network weights after each pattern is presented to the network, the network is updated only after the entire repertoire of patterns to be learned has been presented to the network, at which time the algebraic sums of all the weight changes are applied:2) instead of keeping η, the “learning rate” (i.e., the multiplier on the step size) constant, it is varied dynamically so that the algorithm utilizes a near-optimum η, as determined by the local optimization topography; and3) the momentum factor α is set to zero when, as signified by a failure of a step to reduce the total error, the information inherent in prior steps is more likely to be misleading than beneficial. Only after the network takes a useful step, i.e., one that reduces the total error, does α again assume a non-zero value. Considering the selection of weights in neural nets as a problem in classical nonlinear optimization theory, the rationale for algorithms seeking only those weights that produce the globally minimum error is reviewed and rejected.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of sol gel science and technology 11 (1998), S. 241-250 
    ISSN: 1573-4846
    Keywords: copper phthalocyanine ; dimer ; monomer ; optical absorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Dimer formation in sol-gel matrices was studied using optical absorption spectroscopy of copper phthalocyanine tetrasulfonate dopants in silicate and aluminosilicate sol-gel matrices. Changes in the optical absorption spectra of dimers and monomers were correlated with various stages of the sol-gel process. Dimerization is strongly influenced by the chemistry of the pore liquid. The primary factors that control dimerization are the quantity of solvent remaining in the pores, pore solvent alcohol/water ratio, and presence of protons which can be either from the catalyst or from silanol groups on the silicate pore surfaces. Synthesis conditions which cause dye protonation invariably lead to dimerization during the latter stages of drying when the pore liquid becomes water-rich and there is a high dye concentration. These studies also identify chemical conditions which are able to avoid dye protonation and subsequently reduce dimer formation.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of sol gel science and technology 7 (1996), S. 109-116 
    ISSN: 1573-4846
    Keywords: ferritin ; sol-gel ; magnetism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A significant recent development in sol-gel science has been the encapsulation of biomolecules such as proteins and enzymes in optically transparent silica glasses. This paper reports on the encapsulation of an iron (Fe) storage protein, ferritin, to develop a magnetic silica glass. Native ferritin, which has a nanometer-sized microcrystalline Fe oxide core, was encapsulated in optically transparent silica glasses using the sol-gel process. Fe could be released from ferritin but could not be reconstituted into apoferritin when the protein was trapped in the pores of the glass. Transmission electron microscopy of ferritin-doped aged silica gels indicated that crystallinity of the Fe oxide core was retained upon sol-gel encapsulation. Magnetic measurements on ferritin-doped silica gels indicated the material to be paramagnetic, but not superparamagnetic.
    Type of Medium: Electronic Resource
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