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  • Articles  (174)
  • American Physical Society  (136)
  • Springer  (38)
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  • Physics  (174)
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  • Articles  (174)
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  • 1
    Publication Date: 2012-12-12
    Print ISSN: 0947-8396
    Electronic ISSN: 1432-0630
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Published by Springer
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  • 2
    ISSN: 1435-604X
    Keywords: Keywords: Adenocarcinoma; Aminolaevulinic acid; Barrett's oesophagus; Dysplasia; Photodynamic therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract . Photodynamic therapy (PDT) may have a role in the prevention of oesophageal cancer. Ten patients with Barrett's oesophagus, three with low-grade dysplasia (LGD), four with high-grade dysplasia (HGD), one with carcinoma in situ and two with invasive carcinoma, were treated with PDT. All received 30 mg/kg aminolaevulinic acid (ALA) followed 4 h later by laser endoscopy. Half were treated with red light (630 nm; 100 mW/cm2 for 1000 s) and half with green light (514 nm; 100 mW/cm2 for 500 s). Columnar epithelial regression was seen in all patients with dysplasia (mean area decrease 44%; range 10–100%), with apparent elimination of dysplasia in all cases. In patients with in situ or invasive carcinoma, no response was seen. ALA-induced PDT, using either red or green light, produces effective ablation of dysplastic Barrett's oesophagus, hence may have a role in the prevention of oesophageal carcinoma, but has little effect on in situ or invasive adenocarcinoma.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0630
    Keywords: PACS: 68.55; 72.20; 81.10
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0992-7689
    Keywords: Magnetospheric physics (auroral phenomena; storms and substorms)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Early auroral observations recorded in various oriental histories are examined in order to search for examples of strictly simultaneous and indisputably independent observations of the aurora borealis from spatially separated sites in East Asia. In the period up to AD 1700, only five examples have been found of two or more oriental auroral observations from separate sites on the same night. These occurred during the nights of AD 1101 January 31, AD 1138 October 6, AD 1363 July 30, AD 1582 March 8 and AD 1653 March 2. The independent historical evidence describing observations of mid-latitude auroral displays at more than one site in East Asia on the same night provides virtually incontrovertible proof that auroral displays actually occurred on these five special occasions. This conclusion is corroborated by the good level of agreement between the detailed auroral descriptions recorded in the different oriental histories, which furnish essentially compatible information on both the colour (or colours) of each auroral display and its approximate position in the sky. In addition, the occurrence of auroral displays in Europe within two days of auroral displays in East Asia, on two (possibly three) out of these five special occasions, suggests that a substantial number of the mid-latitude auroral displays recorded in the oriental histories are associated with intense geomagnetic storms.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Climate dynamics 11 (1995), S. 115-128 
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The Southern Oscillation (SO) is examined in three 10 year AMIP-type integrations of a 30-level GCM having prescribed monthly mean observed sea surface temperatures for the period January 1979 to December 1988. Three horizontal spectral resolutions of T21, T42 and T79 are investigated and the results are compared with the low-frequency variability, having periods longer than 8 months, in the observed Darwin and Tahiti sea level pressures (SLP) and in the T106 ECMWF analyses from May 1985 to April 1991. Both the ECMWF analyses and the GCM results give unrealistic SLP variability at Tahiti resulting in low Darwin-Tahiti SLP correlations and low S/N ratios for the Tahiti-Darwin SO index. The ECMWF analyses are in particularly poor agreement with the observations during 1987 with anomalously high SLP at Tahiti. Examination of the ECMWF assimilated SSTs, reveals that this may be related to the assimilated SSTs being too cold in the central and eastern equatorial Pacific during mid-1987. The GCM results show the familiar SLP dipole in the tropical Pacific albeit displaced eastwards compared to previous observational studies especially at T42 resolution, thus accounting for the problems at Tahiti which lies near strong gradients in the correlation pattern. Time-longitude diagrams of low-level convergence and correlation maps of upper-level streamfunction suggest that the model is reproducing the SO divergence anomalies although too weakly at T21 resolution and at different longitudinal locations at T42 and T79 resolutions. The time-mean low-level convergences in the GCM simulations give ITCZs and SPCZs in qualitative agreement with the observations with a tendency for increased convergence in the eastern Pacific ITCZ at higher resolution. Longitudinal shifts are not apparent in the time-mean convergence when comparing the GCM results at different resolutions.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Climate dynamics 11 (1995), S. 115-128 
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract. The Southern Oscillation (SO) is examined in three 10 year AMIP-type integrations of a 30-level GCM having prescribed monthly mean observed sea surface temperatures for the period January 1979 to December 1988. Three horizontal spectral resolutions of T21, T42 and T79 are investigated and the results are compared with the low-frequency variability, having periods longer than 8 months, in the observed Darwin and Tahiti sea level pressures (SLP) and in the T106 ECMWF analyses from May 1985 to April 1991. Both the ECMWF analyses and the GCM results give unrealistic SLP variability at Tahiti resulting in low Darwin-Tahiti SLP correlations and low S/N ratios for the Tahiti-Darwin SO index. The ECMWF analyses are in particularly poor agreement with the observations during 1987 with anomalously high SLP at Tahiti. Examination of the ECMWF assimilated SSTs, reveals that this may be related to the assimilated SSTs being too cold in the central and eastern equatorial Pacific during mid-1987. The GCM results show the familiar SLP dipole in the tropical Pacific albeit displaced eastwards compared to previous observational studies especially at T42 resolution, thus accounting for the problems at Tahiti which lies near strong gradients in the correlation pattern. Time-longitude diagrams of low-level convergence and correlation maps of upper-level streamfunction suggest that the model is reproducing the SO divergence anomalies although too weakly at T21 resolution and at different longitudinal locations at T42 and T79 resolutions. The time-mean low-level convergences in the GCM simulations give ITCZs and SPCZs in qualitative agreement with the observations with a tendency for increased convergence in the eastern Pacific ITCZ at higher resolution. Longitudinal shifts are not apparent in the time-mean convergence when comparing the GCM results at different resolutions.
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  • 7
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract  The total ozone column is well correlated with tropospheric fields such as the heights of the upper tropospheric geopotential surfaces and thus it can provide useful information on temporal variability in the troposphere. The global availability of long period satellite measurements of the total ozone column, taken by the TOMS instruments since 1978, provides a valuable and independent data set for use in studies of seasonal and interannual climate variability. In this study, the global low-frequency seasonal teleconnections in the observed TOMS data from 1979–91 have been investigated using seasonal teleconnectivity maps and empirical orthogonal function analysis. They have also been compared with the results from a simulation made with the atmospheric GCM at Météo-France, having prescribed observed sea surface temperatures for the same period. In the observed total ozone, strong ENSO-related wave number one longitudinal dipole patterns are seen in both the tropics and in the Southern Hemisphere extratropics. The model shows much weaker variability in total ozone yet appears to be able to capture similar teleconnection patterns in the tropics related to ENSO. In the SH extratropics, the model total ozone shows a strong wave number 3 response rather than the wave number one dipole seen in the observations. A wave number 3 response is also evident in the 200 hPa geopotential height simulated by the model and in the NCEP analysis, and is consistent with the response in a linearised barotropic model forced in the Indonesian region. The different responses in the modelled and observed total ozone, suggest that tropopause effect is not the major factor in the SH extratropics, and it is likely that horizontal ozone transport also plays a role in this region. Despite a generally poor simulation of the zonal mean total ozone, the model was able to capture the anomalous strengthening of the SH stationary waves during austral spring of 1988, related to an intense stratosphere sudden warming.
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  • 8
    ISSN: 1573-4994
    Keywords: Cytochrome b5 ; site-directed mutagenesis ; kinetics ; fluorescence ; membrane-binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Cytochrome b5 binds spontaneously to lipid vescles and also self-associates in aqueous solution. Two mutant proteins have been generated, one has a self-association constant which is less than that of the native protein, while the other has a larger self-association constant. All three proteins have Trp in the membrane-binding domain but as aqueous solutions of these proteins contain differing amounts of monomeric protein, the kinetics of fluorescence enhancement, when the proteins are mixed with lipid vesicles, are complex. Similar complex kinetics are seen when the Trp are quenched by the addition of bromolipid vesicles. The mutant which has Trp 108 and 112 both replaced by Leu does not self-associate and shows monoexponential stopped-flow fluorescence kinetics. Identical rate constants are seen with this mutant for fluorescence enhancement by POPC and fluorescence quenching by three bromolipids with bromines at the 6,7-, 9,10-, and 11,12-positions of thesn-2 acyl chain. This rate constant is only 1% of the calculated collisional rate constant and it is suggested that the reduced rate is caused by a reduction in the number of productive collisions rather than by a slow rate of penetration of the membrane-binding domain into the bilayer.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of statistical physics 58 (1990), S. 579-597 
    ISSN: 1572-9613
    Keywords: Logistic map ; Mandelbrot set
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Asymptotic expressions for the positions of the centres (along the real axis) of high-order cycle cardioids closest to the limit point −2 in the Mandelbrot set are obtained by a combination of numerical and analytical methods.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    International journal of thermophysics 14 (1993), S. 541-553 
    ISSN: 1572-9567
    Keywords: amorphous metals ; crystallization ; in situ measurements ; X-ray scattering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Time-resolved X-ray scattering has been used to study the kinetics of crystallization of amorphous metals on time scales varying from minutes to milliseconds. Measurements have been at the National Synchrotron Light Source, using a wide-bandpass monochomator and fast linear position-sensitive detector system at the IBM/MIT beamline X-20C. With this apparatus, scattering patterns from the transforming material can be acquired with 3-ms time resolution. A fast pyrometric temperature controller has been developed to change and regulate the sample temperature with microsecond response. In a typical measurement, two synchronized position-sensitive detectors provide complementaryin situ information about the transformation. The first is used for wide-angle scattering and allows us to determine which phases are present and to what extent. Changes in lattice parameter and particle size can also be deduced. The second detector measures small-angle scattering, yielding additional information about the microstructure, such as the spacing between lammellae in eutectic systems. At relatively slow transformation rates, quantitative measurements of crystal volume fractions as small as 10−4 are possible. In many systems, as the transformation rate is increased, the crystallization mechanism changes such that new metastable crystal phases are formed en route to the equilibrium structure.
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