ALBERT

Description / Table of Contents: 1. Translational Neuroscience of Speech and Language Disorders: State of the Art. -2. Translational Neuroscience of Aphasia and Adult Language Rehabilitation. -3. Treatment and intervention approaches for the improvement of language abilities in neurodegenerative diseases -- 4. Neural and Genetic Mechanisms of Dyslexia -- 5. The role of memory systems in neurodevelopmental disorders of language -- 6. Transcranial direct current stimulation (tDCS) and Language/Speech: Can patients benefit from a combined therapeutic approach? -- 7. Transcranial Magnetic Stimulation in Aphasia Rehabilitation -- 8. The Cerebellum: A Therapeutic Target in Treating Speech and Language Disorders -- 9. Navigated rTMS for Mapping the Language Network in Preoperative Settings: Current Status and Future Prospects -- 10. Presurgical Language fMRI in Epilepsy: An Introduction -- 11. Lesion-symptom mapping in speech and language disorders: a translational perspective.

Description / Table of Contents: Part I. Cancer -- Ubiquitin-Regulated Cell Proliferation and Cancer -- Ubiquitin, SUMO, and Nedd8 as Therapeutic Targets in Cancer -- The Proteasome System in Health and Disease -- Proteostasis Dysregulation in Pancreatic Cancer -- Divergent Modulation of Proteostasis in Prostate Cancer -- Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma -- Part II. Neurodegeneration -- Altered Proteostasis in Neurodegenerative Tauopathies -- The Ubiquitin System in Alzheimer’s Disease -- The Interplay Between Proteostasis Systems and Parkinson’s Disease -- Machado–Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides -- Part III. Infection, Inflammation and Developmental Disorders -- SUMO and Cytoplasmic RNA Viruses: From Enemies to Best Friends -- The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication -- By the Tips of Your Cilia: Ciliogenesis in the Retina and the Ubiquitin-Proteasome System -- TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders -- Part IV. Diet -- We Are What We Eat: Ubiquitin–Proteasome System (UPS) Modulation Through Dietary Products.

Description / Table of Contents: Photoperiodism and Circannual Timing: Introduction and Historical Perspective.-The Pars Tuberalis and Seasonal Timing -- Tanycytes and Their Pivotal Role in Seasonal Physiological Adaptations -- Epigenetic Mechanisms in Developmental and Seasonal Programs -- Plasticity of Neuroendocrine Mechanisms Regulating Seasonal Reproduction in Sheep -- Clocks and Calendrars in Birds -- Calendar Timing in Teleost Fish -- Action of Light on the Neuroendocrine Axis -- Seasons, Clocks, and Mood -- Photoperiodic Modulation of Clock Gene Expression in the SCN -- Circadian Timekeeping in the Suprachiasmatic Nucleus: Genes, Neurotransmitters, Neurons and Astrocytes. .

Description / Table of Contents: Foreword -- Preface -- Introduction -- 1. Physics and radiation dosage issues in neuroradiosurgical treatment of meningiomas -- 2. Imaging Approaches for radiosurgical treatment of Meningiomas -- 3. MEDICAL MANAGEMENT OF MENINGIOMAS -- 4. Systemic Treatments for Grade II and III Meningiomas (WHO) -- 5. Gamma Knife Radiosurgery for Posterior Cranial Fossa Meningioma -- 6. Stereotactic Radiosurgery for Cavernous Sinus Meningiomas -- 7. Hypofractionated radiosurgery for perioptic meningiomas: Current practice, principles and treatment quandary -- 8. Hypofractionation and normofractionation in Skull Base Meningiomas -- 9. Atypical and anaplastic meningiomas: is there a role for stereotactic radiosurgery? -- 10. CyberKnife Treatment of Atypical Meningiomas (GII) -- 11. SRS & Microsurgery: antagonistic or complementary in the treatment of meningiomas? -- 12. Combined microsurgical and radiosurgical treatment in intracranial meningiomas -- 13. SRS in Incidental Meningioma: Whether to Treat and When -- 14. Side-effects of SRS treatment of low-grade meningioma: types, frequency and management -- 15. Single- and Multiple-Session Radiosurgery for Spinal Meningioma: Radiosurgery for spinal meningioma -- 16. Guidelines and evidence-based recommendations for the radiosurgical treatment of CNS meningiomas.

Description / Table of Contents: Preface -- PART 1: To fear or not -- Disambiguating fear as an emotional state vs. threat detection. Molecular and Neural circuits of fear extinction. Psychological and theoretical elements on the concept of fear extinction. Neural circuit of fear extinction: psychophysiology -- PART 2: Individual differences in fear extinction -- The impact of sex differences and sex hormones on fear extinction. Impact of sleep on fear extinction. Impact of stress and exercise on fear extinction. Intersect between the intrinsic and extrinsic factors that modulate fear extinction -- PART 3: Psychopathology -- Fear extinction and its relevance to psychopathology. Developmental fear and its extinction imaging. Fear extinction and adult psychopathology -- Part 4: Therapeutics and neuromodulations of fear extinction -- Exposure therapy and other behavioral therapeutics targeting fear extinction circuits. Novel pharmacotherapeutics targeting fear extinction circuits. Reconsolidation and its link and impact on fear extinction. Technological advances in exposure therapy: virtual and augmented reality. Novel approaches using neurostimulation targeting fear extinction.

Description / Table of Contents: SECTION 1 Status of Observations and Satellite Programs: Chapter 1. The Global Precipitation Measurement (GPM) mission -- Chapter 2. Status of the CloudSat mission -- Chapter 3. The Megha-Tropiques mission after seven years in space -- Chapter 4. Microwave sensors, imagers and sounders -- Chapter 5. Microwave and sub-mm wave sensors: A European perspective -- Chapter 6. Plans for future missions -- SECTION 2 Retrieval Techniques, Algorithms and Sensors: Chapter 7. Introduction to passive microwave retrieval methods -- Chapter 8. The Goddard Profiling (GPROF) precipitation retrieval algorithm -- Chapter 9. Precipitation estimation from the Microwave Integrated Retrieval System (MiRS) -- Chapter 10. Introduction to radar rain retrieval methods -- Chapter 11. Dual-frequency Precipitation Radar (DPR) on the Global Precipitation Measurements (GPM) mission’s Core Observatory -- Chapter 12. DPR dual-frequency precipitation classification -- Chapter 13. Triple-frequency radar retrievals -- Chapter 14. Precipitation retrievals from satellite combined radar and radiometer observations -- Chapter 15. Scattering of hydrometeors -- Chapter 16. Radar snowfall measurement -- Chapter 17. A 1DVar-based snowfall rate algorithm for passive microwave radiometers -- Chapter 18. X-band synthetic aperture radar methods -- SECTION 3 Merged Precipitation Products: Chapter 19. Integrated Multi-satellitE Retrievals for the Global Precipitation Measurement (GPM) mission (IMERG) -- Chapter 20. Global Satellite Mapping of Precipitation (GSMaP) products in the GPM era -- Chapter 21. Improving PERSIANN-CCS using passive microwave rainfall estimation -- Chapter 22. TAMSAT -- Chapter 23. Algorithm and data improvements for version 2.1 of the Climate Hazards Center’s Infrared Precipitation with Stations Data Set -- Chapter 24. Merging the infrared fleet and the microwave constellation for tropical hydrometeorology (TAPEER) and global climate monitoring (GIRAFE) applications -- SECTION 4 Validation: Chapter 25. The IPWG satellite precipitation validation effort -- Chapter 26. The GPM Ground Validation Program -- Chapter 27. The GPM DPR Validation Program -- Chapter 28. Error and uncertainty characterization -- Chapter 29. Multiscale evaluation of satellite precipitation products: Effective resolution of IMERG -- Chapter 30. Remote sensing of orographic precipitation -- Chapter 31. Integrated multi-satellite evaluation for the Global Precipitation Measurement: Impact of precipitation types on spaceborne precipitation estimation -- Chapter 32. Hydrologic validation and flood analysis -- Chapter 33. Global-scale evaluation of 22 precipitation datasets using gauge observations and hydrological modeling -- Chapter 34. OceanRAIN – The global ocean surface-reference dataset for characterization, validation and evaluation of the water cycle -- SECTION 5 Observed Characteristics of Precipitation: Chapter 35. GPCP and the global characteristics of precipitation -- Chapter 36. Global snowfall detection and measurement -- Chapter 37. Snowfall detection by spaceborne radars -- Chapter 38. On the duration and lifecyle of precipitation systems in the tropics -- Chapter 39. Observational characteristics of warm-type heavy rainfall -- Chapter 40. Satellite precipitation measurement and extreme rainfall -- Chapter 41. Rainfall trends in East Africa from an ensemble of IR-based satellite products -- Chapter 42. Heavy precipitation systems in the Mediterranean area: The role of GPM -- Chapter 43. Dryland precipitation climatology from satellite observations -- Chapter 44. Haifall detection -- Chapter 45. Improving high-latitude and cold region precipitation analysis -- Chapter 46. Latent heating retrievals from satellite observations -- SECTION 6 Applications: Chapter 47. Operational applications of Global Precipitation Measurement observations -- Chapter 48. Assimilation of precipitation observations from space into numerical weather prediction (NWP) -- Chapter 49. Precipitation ensemble data assimilation in NWP models -- Chapter 50. PERSIANN-CDR for hydrology and hydro-climatic applications -- Chapter 51. Soil moisture and precipitation: The SM2RAIN algorithm for rainfall retrieval from satellite soil moisture -- Chapter 52. Drought risk management using satellite-based rainfall estimates -- Chapter 53. Two decades of urban hydroclimatological studies have yielded discovery and societal benefits -- Chapter 54. Validation of climate models -- Chapter 55. Extreme precipitation in the Himalayan landslide hotspot -- Chapter 56. The value of satellite rainfall estimates in agriculture and food security -- Chapter 57. Using satellite estimates of precipitation for fire danger rating -- Chapter 58. Variability of satellite sea surface salinity under rainfall.

Description / Table of Contents: Chapter 1 Embryology of the Pineal Gland -- Chapter 2 Anatomy of the Pineal Gland -- Chapter 3 Physiology of the Pineal Gland -- Chapter 4 Neuroimaging of the Pineal Gland -- Chapter 5 Tumors of the Pineal Gland -- Chapter 6 Non-tumorous Lesions of the Pineal Gland -- Chapter 7 Treatment and Approaches for the Pineal Gland Region -- Chapter 8 Interesting Cases of Pineal Gland Diseases and Surgery -- Chapter 9 Animal Based Surgical Training in Pineal Approaches -- Chapter 10 Evolutionary Retrace of the Third Eye.

Description / Table of Contents: High Resolution Imaging Mass Spectrometry of Human Donor Eye: Photoreceptor Cells and Basal Laminar Deposits of Age-related Macular Degeneration -- The non-canonical role of Complement Factor H in Retinal Pigment Epithelium (RPE) cells and implications for Age-related Macular Degeneration -- Macular Pigment Carotenoids and Bisretinoid A2E -- Disturbed matrix metalloproteinases activity in age-related macular degeneraton -- Current views on Chr10q26 contribuiton to age-related macular degeneration -- Untargeted lipidomic profiling of aged human retina with and without age-related macular degeneration (AMD) -- Decoding Race and Age-Relation Macular Degeneration: GPR 143 Activity is the Key -- Peroxisome proliferator-activated receptor gamma coactivator 1 alpha ( PGC-1x): a transcriptional regulator at the interface of aging and age-related macular degeneration? -- Regulation of ABCA1 by miR-33 and miR-34a in the aging eye -- The role of gene expression regulation on genetic risk of Age-related Macular Degeneration -- Elastin layer in Bruch's membrane as a target for immunizatio or tolerization to modulate patthology in the mouse model of somke-induced ocular injury -- Repuprosing drugs for treatment of age-relation macular degeneration -- Extracellular Vesicle RNA Contents as Biomarkers for Ocular Diseases -- Proteomics of retinal extracellular vesicles: a reviw inot an unexplored mechanism in retinal health and AMD pathogenesis -- Prime Editing Strategy to Instally the PRHP2 c.828+1G A mutations -- Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing -- Generation of an Avian Myeloblastosis Virus (AMV) Reverse Transcriptase Prime Editor -- Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy -- Optimization of Capillary-based Western Blotting for MYO7A -- AAV Serotypes and Their Suitability for Retinal Gene Therapy -- Gene Augmentation ofautosomal dominant CRX-associated retinopathies -- Txnip gene therapy of retinitis pigmentosa improves cone health Factors affecting readthrough of natural versus premature termination codons -- Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease -- Network biology and medcine to resuce: Applications for retinal disease mechanisms and therapy -- Non-sydromic Retinal Degeneration Caused by Pathogenic Variants in Joubert Syndrome Genes -- Exonic variants that affect splicing- an opportunity for "hidden" mutations causing inherited retinal diseases -- Enhanced S-cone Syndrome, a Mini-Review -- The role of microglia in Inherited Retinal Diseases -- CD68: potential contributor to inflammation and RPE cell dystrophy -- Gene Expression of Clusterin, Tissue Inhibitor of Metalloproteinase-1, and Their receptors in Retinal Pigment Epithelial Cells and Muller Glial Cells is Modulated by Inflammatory Stresses -- Axonal Transport Defects in Retinal Ganglion Cells -- Connexins biology in the pathophysiology of retinal diseases -- Role of Nuclear NAD +in Retinal Homeostasis -- Retinal pigmented epithelium-derived ectopic norrin does not promote intraretinal angiogenesis in transgenic mice -- Caveolin-1 Muller glia exist as heat-resistant,high molecular weight complexes -- Role of VLC-PUFAs in Retinal and Macular Degeneration -- Ocular amyloid , condensates, and aggregates - higher order protein assemblies participate in both retinal degeneration and function -- Photoreceptor ion channels in signaling and disease -- The role of peripherin-2 /ROM1 complexes in photoreceptor outer segment disc morphogenesis -- Human mutations in Arl3, a small GTPase involved inlipidated cargo delibery to the cilia cause retinatl dystropthy -- Genotype-Phenotype Association in ABCA4-Associated Retinopathy -- Retinal pathoconnectomics: A Window into Neurodegeneration -- The role of Ceramide in Inherited Retinal Disease Pathology -- Extracelluar Matix: the Unexplored Aspects of Retinal Pathologies and Regeneration -- Role of TFEB in diseases assocaited with lysosomal dysfunction -- Retinoic acid receptor -related oprhan receptors (RORs) in eye development and disease -- A novel mouse model for Late-Onset Retinal Degeneration (L-ORD) devekios RPE abnormalities due to the loss of C1qtnf5/Ctrp5 -- Comparison of mouse models of autosomal dominant retinitis pigmentosa due to P23H muations of Rhodopsin -- Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analsyis -- Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Sress and Promotes ER Protein Degradation in Cyclic Nucleotide-gated Channel Deficiency -- Mouse choroid proteome revisited: foucs on aging -- Morphological and functional comparison of mice models for retinitis pigmentosa -- Current Advancements in Mouse Models of Retinal Disease -- Single-cell Itrnacriptomic Profiling of Muller Glia in the rd10 Retina -- Methods for in vivo characterization of proteostatis in the mouse retina -- Absence or PRCD leads to dysregulation in lipie Homeostatis resulting in disorganizationof photorecptor outer segment structure -- Expansion Microscopy of Mouse Photoreceptro Cilia -- Rod photorecptor specific ablation of Metformin target, AMPK, in preclinical model of autosomal recessvie retinitis pigmentosa -- TLR2 is highly overexpressed in retinal myeloid cells in the rd10 mouse model of retinitis pigmentosa -- Environmental light has an essentail effrect on the diseasae expression in a dominant RPE65 mutation -- Microglia Preserve Visual Function in A Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant -- Measuring the release of lactate from wild-type and rd1 mouse retina -- Aerobic glycolysis in photorecptors supports energy demand in the absence of mitochondrial coupling -- Redox Status in Retinitis Pigmentosa -- Perspectives on retinal dolichol metabolism and visual deficits in dolichol metalbolism-associated inherited disorders -- Retinal metabolic profile on IMPG2 deficiency mice with subretinal lesions -- Glutathione-coating of liposomes enhances the delivery of hydrophillic cargo to the inner nuclear layer in retinal cultures -- Modification of Mueller glial cell fate and proliferation with the use of small molecules -- A potential neuroprotective role for pyruvate kinase 2 in retinal degeneration -- Critical role of VEGF as a direct regulator of photorecptor function -- Lysine Ubiquitylation Drives Rhodopsin Protein Turnover -- In-silico prediction of MYO!C Rhodopsin Interactions and its Significance in Protein Localization and Visual Function -- A ciliary branched actin netowrk drives photoreceptor disc morphogenesis -- Revisiting the daily timing of POS phagocytosis -- Inhibition of Bacterial Peoptidoglycan Cytopahty by Retina Pigment Epithelial PGRP2 Amidase -- Understanding ischemic retinopathies: the role of Succinate and its recpto^T mutation -- Inducing neural regeneratio nfrom glia using proneural bHLH transcription factors.