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  • 2020-2024  (15)
  • 1980-1984  (68)
  • 1960-1964  (23)
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  • 1
    Monograph available for loan
    Monograph available for loan
    New York [u.a.] : Wiley
    Call number: AWI G7-93-0181/1 ; AWI G7-93-0181/2
    Description / Table of Contents: Contents: Chapter 1 Late Weichselian lce Sheets in Eurasia and Greenland / Bjöm G. Andersen. - NORTHERN EUROPE. - Holland. - Germany. - Denmark. - Sweden. - Finland. - Poland. - Western USSR (including Baltic SSR). - Northwestern USSR. - Norway. - North Sea. - British Isles. - lceland. - SOUTHERN EUROPE. - BARENTS SEA AND ARCTIC ISLANDS. - ASIA. - GREENLAND. - REFERENCES CITED. - Chapter 2 Late Wisconsin Ice Sheets of North America / Paul A. Mayewski, George H. Denton, Terence J. Hughes. - INTRODUCTION. - LAURENTIDE ICE SHEET. - Eastern Sector. - Southern Sector. - Western Sector. - Northern Sector. - Northeastern Sector. - Interior Sector. - QUEEN ELIZABETH ISLANDS. - Late Wisconsin Maximum. - Late Wisconsin Recession. - CORDILLERAN ICE SHEET. - Late Wisconsin Maximum. - Late Wisconsin Recession. - NORTH AMERICAN ICE SHEETS: AN OVERVIEW . - Maximum and Minimum. - Reconstructions. - Fundamental Questions About Late Wisconsin Deglaciation. - Glaciological Speculations. - REFERENCES CITED. - APPENDIX. - Chapter 3 Late Wisconsin-Weichselian Mountain Glaciers and Small Ice Caps / John T. Hollin, David H. Schiling. - INTRODUCTION. - ALASKA. - WESTERN UNITED STATES. - MEXICO AND CENTRAL AMERICA. - SOUTH AMERICA. - Venezuela. - Colombia. - Ecuador. - Peru. - Bolivia. - Chile and Argentina to Lat 36°30'S. - Chile and Argentina South of Lat 36°30'S. - Islas Juan Fernandez. - Falkland Islands (Islas Malvinas). - Brazil. - Areas and Volumes. - NEWZEALAND. - AUSTRALIA, NEW GUINEA, AND SABAH. - The Australian Mainland. - Tasmania. - New Guinea and Sabah. - Conclusions. - AFRICA. - Northwest Africa and Atlantic Islands. - Mountains in Ethiopia. - Mountains Surrounding Lake Victoria. - South and West Africa. - SUBANTARCTIC ISLANDS. - CONCLUSIONS. - REFERENCES CITED. - Chapter 4 Numerical Reconstruction of Valley Glaciers and Small Ice Caps / David H. Schilling, John T. Hollin. - INTRODUCTION. - VALLEY GLACIERS AND PERFECT PLASTICITY. - The Iterative Scheme. - The Shape Factor. - Choice of the Yield Stress. - Choice of Step Length, [Delta x]. - The First Step and the Snout. - Steep and Mountainous Areas. - The VALLEY Program. - ICE CAPS, WITH SLIDING AND ABLATION. - Perfect Plasticity. - Law of Sliding and Iterative Scheme. - The ABLATE Program. - Various Models and the Flow Law. - An Application of the ABLATE Program. - Some Remaining Problems. - CONCLUSIONS. - REFERENCES CITED. - Chapter 5 Numerical Reconstruction of Paleo-Ice Sheets / Terence J. Hughes. - ICE-BED COUPLING AND SUBGLACIAL HYDROLOGY. - SUBGLACIAL HYDROLOGY AND EROSION-DEPOSITION PROCESSES. - TOPOGRAPHIC CRITERIA FOR RECONSTRUCTING FORMER ICE SHEETS. - Subglacial Landscapes. - Ice Domes. - Ice Saddles. - Melting Zone. - Equilibrium Zone. - Freezing Zone. - Ice Streams. - BASIC EQUATIONS FOR STEADY-STATE CREEP IN ICE SHEETS. - BASAL SHEAR STRESS AND TWO-DIMENSIONAL LAMINAR FLOW. - BASAL SHEAR STRESS AND BASAL SLIDING. - BASAL SHEAR STRESS AND CONSTRUCTING ICE-SHEET PROFILES. - BASAL SHEAR STRESS FOR FROZEN AND MELTED BEDS. - BASAL SHEAR STRESS FOR FREEZING AND MELTING BEDS. - BASAL SHEAR STRESS FOR ICE STREAMS AND ICE LOBES. - BASAL SHEAR STRESS FOR ICE DIVIDES. - EVALUATING TERMS IN THE FLOW AND SLIDING LAWS FOR GLACIAL ICE. - RADIAL FLOW AND SNOW ACCUMULATION FOR ICE DOMES. - LATERAL SHEAR AND DOWNDRAW FOR ICE STREAMS. - ISOSTATIC ADJUSTMENTS BENEATH ICE SHEETS. - SUMMARY. - REFERENCES CITED. - Chapter 6 The Last Great Ice Sheets: A Global View / Terence J. Hughes, George H. Denton, Björn G. Andersen, David H. Schilling, James L. Fastook, Craig S. Lingle. - AREAL EXTENT OF LATE WISCONSIN-WEICHSELIAN ICE SHEETS. - North America. - Greenland. - Eurasia. - Antarctica. - Minimum and Maximum. - Reconstructions of Late Wisconsin-Weichselian Ice Extent. - VERTICAL EXTENT OF LATE WISCONSIN-WEICHSELIAN ICE SHEETS. - The Critical Problem of Marine Ice Sheets. - Flowline Profiles for Variable Bed Topography. - Flowline Profiles for Variable Isostatic Compensation. - Flowline Profiles for Variable Basal Shear Stress. - Flowline Profiles for Present-day Ice Sheets. - Flowline Profiles for Late Wisconsin-Weichselian Ice Sheets. - Isostatic Conditions for Late Wisconsin-Weichselian Ice Sheets. - Basal Conditions for Late Wisconsin-Weichselian Ice Sheets. - Elevations and Volumes of Late Wisconsin-Weichselian Ice Sheets. - DISCUSSION. - REFERENCES CITED. - Chapter 7 History of the Marine Ice Sheet In West Antarctica During the Last Glaciation: A Working Hypothesis / Minze Stuiver, George H. Denton, Terence J. Hughes, James L. Fastook. - INTRODUCTION . - McMURDO SOUND AREA. - Ross Sea Drift: Description. - Ross Sea Drift: Interpretation. - Radiometric Dates and Ross Sea Drift. - Older Drift: Description and Interpretation. - Discussion. - TERRA NOVA BAY. - BEAUFORT AND FRANKLIN ISLANDS. - GLACIAL-MARINE SEDIMENTS IN THE ROSS SEA. - RECONSTRUCTION OF LATE WISCONSIN ANTARCTIC ICE SHEET. - Geologic Background. - Glaciological Background: Steady-State Model. - Conclusions. - DISINTEGRATION OF MARINE ICE SHEET IN WEST ANTARCTICA. - Disintegration Model. - Disintegration of Ice Shelves. - Late Wisconsin-Holocene Disintegration. - Disintegration during Super Interglacials. - SUMMARY. - REFERENCES CITED. - Chapter 8 The Arctic Ice Sheet: An Outrageous Hypothesis / George H. Denton, T erence J. Hughes. - ICE-SHELF ORIGIN OF NORTHERN HEMISPHERE ICE DOMES. - Growth Rates of Arctic Ice Domes. - Sites for lnitiating Arctic Ice Domes. - Thickening Rates of Arctic Sea Ice. - Sites for Grounding Arctic Sea Ice. - Forming Arctic Ice Shelves on Deep Oceans. - Assessing the lce-Shelf Hypothesis for Forming Marine Ice Domes. - LA TE WISCONSIN-WEICHSELIAN ARCTIC ICE SHEET. - Ice Domes. - Ice Streams. - Ice Shelves. - DISINTEGRATION OF LATE WISCONSIN-WEICHSELIAN ARCTIC ICE SHEET. - Initiation of Late Wisconsin-Weichselian Glacial Surges. - Maintenance of Late Wisconsin-Weichselian Glacial Surges. - Environmental Impact of Late Wisconsin-Weichselian Glacial Surges. - CONCLUSIONS. - REFERENCES CITED. - INDEX.
    Type of Medium: Monograph available for loan
    Pages: XVIII, 484 S. : Ill., Kt. ; 27 Kt.-Beil.
    ISBN: 0471060062
    Series Statement: A Wiley interscience publication
    Location: AWI Reading room
    Location: AWI Reading room
    Branch Library: AWI Library
    Branch Library: AWI Library
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  • 2
    Publication Date: 2024-04-20
    Description: This dataset contains the gridded correlation results from a study that sought to better understand the climatic footprint monitored by antipodal mid-latitude glacier populations. Understanding the links between glaciers and climate is critical for accurately interpreting contemporary cryosphere changes, and interrogating the causes of past glacier behavior. However, work is still needed to refine the extent to which they capture regional to hemisphere-scale atmospheric processes. A Pearson's correlation was performed between yearly summer seasonal data from the ERA5 gridded reconstructions of global temperature and wind changes on each available ERA5 pressure level and yearly glacier snowline/ELA elevations in the Southern Alps of New Zealand and in the European Alps. December-Febuary austral summer data was correlated with the Southern Alps records and June-August Northern Hemisphere summer data was correlated with the European Alps. The ERA5 input dataset was regridded onto a new monthly axis representing the true month lengths. Then the weighted seasonal average (December-February and June-August) was calculated. Individuals glaciers with Equilibrium Line Altitude (ELA; European Alps) and End of Summer Snowlines (EOSS; Southern Alps) were selected with respective records covering at least 80% of the 1979-2017/15 analysis period. The records from each glacier were then standardized and an EOF analysis was performed to obtain each location's First Principle Component for input into the Pearson's Correlation. A nearly identical set of analyses was performed using weather stations temperature data instead of glacier ELA/snowlines. The New Zealand station equivalent is from the National Institute of Water and Atmospheric Research (NIWA) New Zealand seven-station (NZ7S) series. The European Alps equivalent is from the HistAlp regional weather station syntheses. This companion analysis allows the glacier's ability to record the climate to be compared to that of meteorological instruments.
    Keywords: Alps; Binary Object; Binary Object (File Size); correlation; ERA5; European Alps; File content; glacier; New Zealand; Southern Hemisphere Westerly Winds; Westerlies
    Type: Dataset
    Format: text/tab-separated-values, 14 data points
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  • 3
    Publication Date: 2024-04-01
    Description: In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich, chemical entities that comply with the following criteria; MW ≤ 300, cLogP ≤ 3, H-Bond Acceptors ≤ 3, H-Bond Donors ≤ 3, Rotatable bonds (Flexibility Index) ≤ 3, Polar Surface Area ≤ 60 Å2 and aqueous solubility ≥ 1 mM using LogS and high purity (≥ 95%). Comparisons between two different screening methods, a coupled enzyme activity assay and differential scanning fluorimetry, has allowed identification of compounds that interact and inhibit the T. brucei choline kinase, several of which possess selective trypanocidal activity. Screening of a comparatively small fragment library by two different screening methods has allowed identification of several compounds that interact with and inhibit TbCK, a genetically validated drug target against African sleeping sickness. Some of the inhibitory fragments were also selectively trypanocidal, considering these are relatively simple molecules with no optimization, finding low μΜ inhibitors is very encouraging. Moreover some of the morphological phenotypes of these trypanocidal compounds include cell-cycle arrests similar to those observed for the TbCK conditional knockout grown under permissive conditions.
    Keywords: pharmacology ; toxicology ; pharmacology ; toxicology ; Assay ; Enzyme ; Molar concentration ; Protein ; Thermal shift assay ; Trypanosoma brucei ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
    Language: English
    Format: image/jpeg
    Format: image/jpeg
    Format: image/jpeg
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  • 4
    Publication Date: 2024-01-20
    Description: Automated bioacoustic analysis aids understanding and protection of both marine and terrestrial \nanimals and their habitats across extensive spatiotemporal scales, and typically involves analyzing \nvast collections of acoustic data. With the advent of deep learning models, classifcation of important \nsignals from these datasets has markedly improved. These models power critical data analyses for \nresearch and decision-making in biodiversity monitoring, animal behaviour studies, and natural \nresource management. However, deep learning models are often data-hungry and require a signifcant \namount of labeled training data to perform well. While sufcient training data is available for certain \ntaxonomic groups (e.g., common bird species), many classes (such as rare and endangered species, \nmany non-bird taxa, and call-type) lack enough data to train a robust model from scratch. This study \ninvestigates the utility of feature embeddings extracted from audio classifcation models to identify \nbioacoustic classes other than the ones these models were originally trained on. We evaluate models \non diverse datasets, including diferent bird calls and dialect types, bat calls, marine mammals calls, \nand amphibians calls. The embeddings extracted from the models trained on bird vocalization data \nconsistently allowed higher quality classifcation than the embeddings trained on general audio \ndatasets. The results of this study indicate that high-quality feature embeddings from large-scale \nacoustic bird classifers can be harnessed for few-shot transfer learning, enabling the learning of new \nclasses from a limited quantity of training data. Our fndings reveal the potential for efcient analyses \nof novel bioacoustic tasks, even in scenarios where available training data is limited to a few samples.
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 11 (1963), S. 22-26 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 106 (1963), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 54 (1982), S. 81-84 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 21 (1982), S. 5155-5163 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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