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  • 1
    Monograph available for loan
    Monograph available for loan
    Examples of improvements to clutter suppression in current operational weather radar systems (1994)
    Offenbach (Main) : DWD, Abt. Forschung
    Associated volumes
    Details Availability
    Call number: MOP Per 900(19)
    In: Arbeitsergebnisse
    Type of Medium: Monograph available for loan
    Pages: 7 Bl. : graph. Darst.
    Series Statement: Arbeitsergebnisse / Deutscher Wetterdienst, Abteilung Forschung 19
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 2
    Electronic Resource
    Electronic Resource
    Volume and heat capacity changes upon ionization of water, acetic acid, n-propylamine, and 4-methylimidazole in water and 8 M urea: consequences of ionization on properties of proteins (1984)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 88 (1984), S. 3348-3356 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j150659a043
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  • 3
    Electronic Resource
    Electronic Resource
    Regulation of mRNA Stability in Development (1994)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 28 (1994), S. 263-282 
    Details
    ISSN: 0066-4197
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ge.28.120194.001403
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  • 4
    Electronic Resource
    Electronic Resource
    Über die Struktur der Acrylnitril-Guanidin-Kondensate Über Heterocyclen, 78. Mitt. (1984)
    Springer
    Monatshefte für Chemie 115 (1984), S. 445-453 
    Details
    ISSN: 1434-4475
    Keywords: Guanidine ; N,N-bis(2-cyanoethyl) ; hydrochloride ; 2H-Pyrimido[1,2—a]pyrimidin-2,8(1H)-diimine ; 3,4,6,7-tetrahydro ; picrate and sulfate ; Pyrimidine-1-propionitrile ; 1,4,5,6-tetrahydro-2-amino-4-imino and -4-oxo ; picrates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Repetition of the work ofSugino andTamaka 1 showed that acrylonitrile and guanidine react inDMF to yield not only 3,4,6,7-tetrahydro-2H-pyrimido[1,2—a]pyrimidine-2,8(1H)-diimine (1), but a mixture (F) of1 (as a main product) and 2-amino-4-imino-1,4,5,6-tetrahydropyrimidine-1-propionitrile (7) besides one or two bases not identified so far.1 and7 were isolated as picrates. For the prove of their structures,1- and7-picrate were also prepared by an unequivocal synthesis starting from iminodipropionitrile hydrochloride8 · HCl: The latter on reaction with cyanamide gave9 which cyclized to afford a mixture of1,7 and 2-amino-4-oxo-1,4,5,6-tetrahydropyrimidine-1-propionitrile (10). The picrates of1 and7 were identical with those prepared from the acrylonitrileguanidine-condensateF. This result supports the prior proposed1 structures of pyrimidopyrimidine1 and of4,5 and6, obtained by hydrolysis of1. Nmr-, ir-and some of the mass spectra of1,4,7–10 (and their salts) are reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00810006
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  • 5
    Electronic Resource
    Electronic Resource
    Synthesis and ring transformation of novel tetracyclic fused as-triazines (1992)
    Springer
    Monatshefte für Chemie 123 (1992), S. 1181-1191 
    Details
    ISSN: 1434-4475
    Keywords: Ring transformation ; as-Triazines, fused ; Alkylation ; Regioselectivity ; Calculation, AM1 ; Annelation effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Acht neue tetracyclische kondensierte as-Triazine (4–6,8,11–13 und15) wurden durch Reaktion und nachfolgende Ringtransformierung von 1,2-Diaminoisochinolinium (2) bzw. -chinoliniumsalzen (9) mit 4-Benzoyl-5-phenylfuran-2,3-dion (1) dargestellt. Die selektiven Alkylierungen wiesen darauf hin, daß diese Reaktionen hauptsächlich sowohl durch die Elektronendichte der freien Elektronpaare als auch durch sterische Effekte beeinflußt werden.
    Notes: Summary Eight new tetracyclic fused as-triazines (4–6,8,11–13, and15) have been synthesized by conversion and subsequent ring transformation of 1,2-diaminoisoquinolinium (2) and -quinolinium salts (9) with 4-benzoyl-5-phenylfuran-2,3-dione (1). Selective alkylations of the new products revealed that these reactions are governed mainly by the electronic density of the lone pairs as well as by steric effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00808281
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  • 6
    Electronic Resource
    Electronic Resource
    Circadian control of oviposition in the codling moth, Laspeyresia pomonella, Lepidoptera: Olethreutidae (1980)
    Springer
    Entomologia experimentalis et applicata 27 (1980), S. 38-49 
    Details
    ISSN: 1570-7458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Der Eiablagerhythmus von Laspeyresia pomonella (L.) wird von Licht-Dunkel-Zyklen gesteuert und läuft frei im Dauerlicht mit einer Periode τ=25.9 St. und im Dauerdunkel mit τ=21.8 St. Im Labor sowie unter natürlichen Bedingungen lag der 50%-Punkt der täglichen Eiablage jeweils 2.5 St. vor dem Beginn der Dunkelheit. Der Apfelwickler kann sich rasch an ein verändertes Lichtregime anpassen. Nach mehreren Tagen Freilauf im Dauerlicht synchronisierte sich der Eiablagerhythmus innerhalb von 48 St. mit einem normalen Licht-Dunkel-Zyklus.
    Notes: Abstract The oviposition rhythm in Laspeyresia pomonella (L.) is entrained by light-dark cycles and freeruns in continuous light with a period τ=25.9 hr and in continuous darkness with τ=21.8 hr. In the laboratory as well as in the field, the median of oviposition occurs on average 2.5 hr before the onset of darkness. The codling moth can adapt quickly to a new light regime. Oviposition was resynchronized with a normal light-dark cycle within 48 hr after freerunning for several days in continuous light.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00377238
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  • 7
    Electronic Resource
    Electronic Resource
    Das Studium der Überführung von Progesteron in Testololacton (1956)
    Springer
    Naturwissenschaften 43 (1956), S. 471-471 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00621928
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  • 8
    Electronic Resource
    Electronic Resource
    Evidence of forces produced by bilayers composed of long molecules (1980)
    Springer
    Naturwissenschaften 67 (1980), S. 416-417 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00405495
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  • 9
    Electronic Resource
    Electronic Resource
    Phase I clinical and pharmacokinetic trial of dextran conjugated doxorubicin (AD-70, DOX-OXD) (1993)
    Springer
    Investigational new drugs 11 (1993), S. 187-195 
    Details
    ISSN: 1573-0646
    Keywords: phase I ; dextran-conjugated doxorubicin ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Coupling of anthracyclines to high-molecular-weight carriers may alter drug disposition and improve antitumor effects. We have performed a clinical phase I trial of doxorubicin coupled to dextran (70000 m.w.). The drug was administered as single dose i.v. every 21–28 days. Thirteen patients have received a total of 24 courses (median 2; range 1–3). At the starting dose of 40 mg/m2 doxorubicin equivalent (DOXeq), WHO grade IV thrombocytopenia was noted in 2/2 patients. WHO grade IV hepatotoxicity and WHO grade III cardiotoxicity were noted in a patient with preexisting heart disease. Five patients were treated with 12.5 mg/m2 DOXeq. Maximal toxicity at this dose level was WHO grade III thrombocytopenia and local phlebitis (WHO grade II) in 1/5 patients, elevation of alkaline phosphatase (WHO grade III) and WHO grade III vomiting in another patient. Subsequently, five patients received 20 mg/m2 DOXeq. Hepatotoxicity was noted in 5/5 patients (1 × WHO grade IV, 1 × WHO grade III). Thrombocytopenia was noted in 3/5 patients (1 × WHO grade IV, 2 × WHO grade III). At 12.5 mg/m2 DOXeq, a patient diagnosed with a malignant fibrous histiocytoma had stable disease for 4 months. Pharmacokinetic analyses of total and free doxorubicin were performed in plasma and urine. The maximum peak plasma concentration (ppc) for total DOX was 12.3 μg/ml at 40 mg/m2 DOXeq. The area under the plasma concentration time curve (AUC) ranged from 28.83–80.21 μg/ml*h with dose-dependent elimination half lives (t1/2α: 0.02–0.87 h;1/2β: 2.69–11.58 h;1/2γ: 41.44–136.58 h). We conclude that the maximal tolerated dose (MTD) of AD-70 using this schedule is 40 mg/m2 DOXeq. The recommended dose for clinical phase II studies is 12.5 mg/m2 DOXeq.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00874153
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  • 10
    Electronic Resource
    Electronic Resource
    Push: An experimental facility for implementing distributed database services in operating systems (1993)
    Springer
    Journal of systems integration 3 (1993), S. 5-21 
    Details
    ISSN: 1573-8787
    Keywords: Operating Systems ; database ; communications ; extensible ; adaptable
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Distributed database systems need speciaal operating system support. Support routines can be implemented inside the kernel or at the user level. Kernel-level functions, while efficient, are hard to implement. User-level implementations are easier but suffer from poor performance and lack of security. This article proposes a new approach to supplement or modify kernel facilities for database transaction processing. Our experimental facility, called Push, is based on an extension language interpreted within the kernel. Our implementation provides the efficiency of kernel-resident code as well as the simplicity and safety of user-level programming. This facility enables experimentation that would be difficult and time-consuming in current environments. The overhead of the Push implementation can be factored out to give a good estimate of the performance of a native kernel implementation. We have used Push to implement several kernel-resident services. In the case of multi-RPC and commit protocols, Push implementations significantly improve performance and scalability over user-level implementations. The experiments show the benefits of Push both as an operational tool for improving transaction processing performance and as an experimental tool for investigating the benefits of operating systems extension without costly implementation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01974169
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