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Digitale Medien

Recent Nuclear Structure Studies in Rapidly Rotating Nuclei (1986)

Garrett, J D ; Hagemann, G B ; Herskind, B

Palo Alto, Calif. : Annual Reviews

Annual Review of Nuclear and Particle Science 36 (1986), S. 419-473

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ISSN: 0163-8998

Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff

Thema: Physik

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1146/annurev.ns.36.120186.002223

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Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer (2016)

Khaled Ali; Dalya R. Soond; Roberto Piñeiro; Thorsten Hagemann; Wayne Pearce; Ee Lyn Lim; Hicham Bouabe; Cheryl L. Scudamore; Timothy Hancox; Heather Maecker; Lori Friedman; Martin Turner; Klaus Okkenhaug; Bart Vanhaesebroeck

Springer Nature

In: Nature

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Publikationsdatum: 2016-07-28

Beschreibung: Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer Nature 535, 7613 (2016). doi:10.1038/nature17641 Authors: Khaled Ali, Dalya R. Soond, Roberto Piñeiro, Thorsten Hagemann, Wayne Pearce, Ee Lyn Lim, Hicham Bouabe, Cheryl L. Scudamore, Timothy Hancox, Heather Maecker, Lori Friedman, Martin Turner, Klaus Okkenhaug & Bart Vanhaesebroeck Nature510, 407–411 (2014); doi:10.1038/nature13444Queen Mary University London notified Nature and University College London that there is reason to question the provenance of the data for Fig. 5b, d, e of this Letter (Fig. 5a, c

Print ISSN: 0028-0836

Digitale ISSN: 1476-4687

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von Springer Nature

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Impact of soil moisture-climate feedbacks on CMIP5 projections: First results from the GLACE-CMIP5 experiment (2013)

Sonia I. Seneviratne, Micah Wilhelm, Tanja Stanelle, Bart Hurk, Stefan Hagemann, Alexis Berg, Frederique Cheruy, Matthew E. Higgins, Arndt Meier, Victor Brovkin, Martin Claussen, Agnès Ducharne, Jean-Louis Dufresne, Kirsten L. Findell, Joséfine Ghattas, David M. Lawrence, Sergey Malyshev, Markku Rummukainen, Ben Smith

Wiley

In: Geophysical Research Letters

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Publikationsdatum: 2013-09-14

Beschreibung: [1] GLACE-CMIP5 is a multi-model experiment investigating the impact of soil moisture-climate feedbacks in CMIP5 projections. We present here first GLACE-CMIP5 results based on five Earth System Models, focusing on impacts of projected changes in regional soil moisture dryness (mostly increases) on late 21 st -century climate. Projected soil moisture changes substantially impact climate in several regions in both boreal and austral summer. Strong and consistent effects are found on temperature, especially for extremes (about 1–1.5 K for mean temperature and 2–2.5 K for extreme daytime temperature). In the Northern Hemisphere, effects on mean and heavy precipitation are also found in most models, but the results are less consistent than for temperature. A direct scaling between soil moisture-induced changes in evaporative cooling and resulting changes in temperature mean and extremes is found in the simulations. In the Mediterranean region, the projected soil moisture changes affect about 25% of the projected changes in extreme temperature.

Print ISSN: 0094-8276

Digitale ISSN: 1944-8007

Thema: Geologie und Paläontologie , Physik

Publiziert von Wiley im Namen von American Geophysical Union (AGU).

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Structure and properties of complex hydride perovskite materials (2014)

Pascal Schouwink; Morten B. Ley; Antoine Tissot; Hans Hagemann; Torben R. JensenĽubomír Smrčok; Radovan Černý

Springer Nature

In: Nature Communications

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Publikationsdatum: 2014-12-12

Beschreibung: Article Complex metal hydrides are of interest for applications such as hydrogen storage, solid-state phosphors and solid electrolytes. Here the authors present the synthesis and properties of 30 complex hydride compounds with a perovskite crystal structure, based on the BH4 − anion and new synthesis protocols involving rare-earth elements. Nature Communications doi: 10.1038/ncomms6706 Authors: Pascal Schouwink, Morten B. Ley, Antoine Tissot, Hans Hagemann, Torben R. Jensen, Ľubomír Smrčok, Radovan Černý

Digitale ISSN: 2041-1723

Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft , Physik

Publiziert von Springer Nature

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Asian Irrigation, African Rain: Remote Impacts of Irrigation (2016)

Philipp Vrese, Stefan Hagemann, Martin Claussen

Wiley

In: Geophysical Research Letters

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Publikationsdatum: 2016-03-10

Beschreibung: Irrigation is not only vital for global food security, but also constitutes an anthropogenic land-use change, known to have strong effects on local hydrological and energy cycles. Using the Max Planck Institute for Meteorology's Earth System Model we show that related impacts are not confined regionally, but that possibly as much as 40% of the present-day precipitation in some of the arid regions in Eastern Africa are related to irrigation-based agriculture in Asia. Irrigation in South Asia also substantially influences the climate throughout Southeast Asia and China via the advection of water vapor and by altering the Asian monsoon. The simulated impact of irrigation on remote regions is sensitive to the magnitude of the irrigation-induced moisture flux. Therefore, it is likely that a future extension or decline of irrigated areas due to increasing food demand or declining fresh water resources will also affect precipitation and temperatures in remote regions.

Print ISSN: 0094-8276

Digitale ISSN: 1944-8007

Thema: Geologie und Paläontologie , Physik

Publiziert von Wiley im Namen von American Geophysical Union (AGU).

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Genomic encoding of transcriptional burst kinetics (2019)

Anton J. M. Larsson, Per Johnsson, Michael Hagemann-Jensen, Leonard Hartmanis, Omid R. Faridani, Björn Reinius, Åsa Segerstolpe, Chloe M. Rivera, Bing Ren, Rickard Sandberg

Springer Nature

In: Nature

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Publikationsdatum: 2019

Print ISSN: 0028-0836

Digitale ISSN: 1476-4687

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von Springer Nature

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Influence of land-atmosphere feedbacks on temperature and precipitation extremes in the GLACE-CMIP5 ensemble (2015)

Ruth Lorenz, Daniel Argüeso, Markus G. Donat, Andrew J. Pitman, Bart van den Hurk, Alexis Berg, David M. Lawrence, Frédérique Chéruy, Agnès Ducharne, Stefan Hagemann, Arndt Meier, P. C. D. Milly, Sonia I. Seneviratne

Wiley

In: Journal of Geophysical Research JGR - Atmospheres

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Publikationsdatum: 2015-12-17

Beschreibung: We examine how soil moisture variability and trends affect the simulation of temperature and precipitation extremes in six global climate models using the experimental protocol of the Global Land-Atmosphere Coupling Experiment of the Coupled Model Intercomparison Project, Phase 5 (GLACE-CMIP5). This protocol enables separate examinations of the influences of soil moisture variability and trends on the intensity, frequency and duration of climate extremes through to the end of the 21 s t century under a business-as-usual (RCP8.5) emission scenario. Removing soil moisture variability significantly reduces temperature extremes over most continental surfaces while wet precipitation extremes are enhanced in the tropics. Projected drying trends in soil moisture lead to increases in intensity, frequency, and duration of temperature extremes by the end of the 21 s t century. Wet precipitation extremes are decreased in the tropics with soil moisture trends in the simulations while dry extremes are enhanced in some regions, in particular the Mediterranean and Australia. However, the ensemble results mask considerable differences in the soil moisture trends simulated by the six climate models. We find that the large differences between the models in soil moisture trends, which are related to an unknown combination of differences in atmospheric forcing (precipitation, net radiation), flux partitioning at the land surface, and how soil moisture is parameterized, imply considerable uncertainty in future changes in climate extremes.

Print ISSN: 0148-0227

Thema: Geologie und Paläontologie , Physik

Publiziert von Wiley im Namen von American Geophysical Union (AGU).

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ADAM8 as a drug target in pancreatic cancer (2015)

Uwe Schlomann; Garrit Koller; Catharina Conrad; Taheera Ferdous; Panagiota Golfi; Adolfo Molejon Garcia; Sabrina Höfling; Maddy Parsons; Patricia Costa; Robin Soper; Maud Bossard; Thorsten Hagemann; Rozita Roshani; Norbert Sewald; Randal R. Ketchem; Marcia L. Moss; Fred H. Rasmussen; Miles A. Miller; Douglas A. Lauffenburger; David A. Tuveson; Christopher Nimsky; Jörg W. Bartsch

Springer Nature

In: Nature Communications

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Publikationsdatum: 2015-01-30

Beschreibung: Article Expression of ADAM8, a metalloprotease disintegrin, correlates with worse prognosis in pancreatic adenocarcinoma (PDAC). Here Schlomann et al . show that ADAM8 promotes PDAC invasiveness, and develop a peptide inhibitor that blocks ADAM8 function and impedes PDAC progression in mouse models. Nature Communications doi: 10.1038/ncomms7175 Authors: Uwe Schlomann, Garrit Koller, Catharina Conrad, Taheera Ferdous, Panagiota Golfi, Adolfo Molejon Garcia, Sabrina Höfling, Maddy Parsons, Patricia Costa, Robin Soper, Maud Bossard, Thorsten Hagemann, Rozita Roshani, Norbert Sewald, Randal R. Ketchem, Marcia L. Moss, Fred H. Rasmussen, Miles A. Miller, Douglas A. Lauffenburger, David A. Tuveson, Christopher Nimsky, Jörg W. Bartsch

Digitale ISSN: 2041-1723

Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft , Physik

Publiziert von Springer Nature

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Nitric oxide mediates glial-induced neurodegeneration in Alexander disease (2015)

Liqun Wang; Tracy L. Hagemann; Hermann Kalwa; Thomas Michel; Albee Messing; Mel B. Feany

Springer Nature

In: Nature Communications

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Publikationsdatum: 2015-11-28

Beschreibung: Article Alexander disease is a rare neurological disorder caused by mutations in GFAP, yet it is unclear how glial disruptions lead to neural death. Here, Wang et al . identify a mechanism by which glial-derived nitric oxide leads to neuronal degeneration in fly and mouse models of the disease. Nature Communications doi: 10.1038/ncomms9966 Authors: Liqun Wang, Tracy L. Hagemann, Hermann Kalwa, Thomas Michel, Albee Messing, Mel B. Feany

Digitale ISSN: 2041-1723

Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft , Physik

Publiziert von Springer Nature

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On the contribution of statistical bias correction to the uncertainty in the projected hydrological cycle (2011)

Cui Chen, Jan O. Haerter, Stefan Hagemann and Claudio Piani

Wiley

In: Geophysical Research Letters

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Publikationsdatum: 2011-10-26

Beschreibung: Global hydrological modeling is affected by three sources of uncertainty: (i) the choice of the global climate model (GCM) used to provide meteorological forcing data; (ii) the choice of future greenhouse gas concentration scenario; and (iii) the choice of the decade used to derive the bias correction parameters. We present a comparative analysis of these uncertainties and compare them to the inter-annual variability. The analysis focuses on discharge, integrated runoff and total precipitation over ten large catchments, representative of different climatic areas of the globe. Results are similar for all catchments, all hydrological variables and throughout the year with few exceptions. We find that the choice of different decadal periods over which to derive the bias correction parameters is a source of comparatively minor uncertainty, while other sources play larger and similarly significant roles. This is true for both the means and the extremes of the studied hydrological variables.

Print ISSN: 0094-8276

Digitale ISSN: 1944-8007

Thema: Geologie und Paläontologie , Physik

Publiziert von Wiley im Namen von American Geophysical Union (AGU).

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