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  • Molecular Sequence Data  (2)
  • *Zea mays/growth & development  (1)
  • 2005-2009  (3)
  • 1990-1994
  • 2009  (3)
  • 1
    Publication Date: 2009-06-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vitousek, P M -- Naylor, R -- Crews, T -- David, M B -- Drinkwater, L E -- Holland, E -- Johnes, P J -- Katzenberger, J -- Martinelli, L A -- Matson, P A -- Nziguheba, G -- Ojima, D -- Palm, C A -- Robertson, G P -- Sanchez, P A -- Townsend, A R -- Zhang, F S -- New York, N.Y. -- Science. 2009 Jun 19;324(5934):1519-20. doi: 10.1126/science.1170261.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Stanford University, Stanford, CA 94305, USA. vitousek@stanford.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19541981" target="_blank"〉PubMed〈/a〉
    Keywords: *Agriculture/methods ; China ; Environmental Pollution ; Fertilizers ; Kenya ; Nitrogen ; Phosphorus ; *Soil ; United States ; *Zea mays/growth & development
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2009-11-26
    Description: The Hedgehog (Hh) signaling pathway plays multiple essential roles during metazoan development, homeostasis, and disease. Although core protein components are highly conserved, the variations in Hh signal transduction mechanisms exhibited by existing model systems (Drosophila, fish, and mammals) are difficult to understand. We characterized the Hh pathway in planarians. Hh signaling is essential for establishing the anterior/posterior axis during regeneration by modulating wnt expression. Moreover, RNA interference methods to reduce signal transduction proteins Cos2/Kif27/Kif7, Fused, or Iguana do not result in detectable Hh signaling defects; however, these proteins are essential for planarian ciliogenesis. Our study expands the understanding of Hh signaling in the animal kingdom and suggests an ancestral mechanistic link between Hh signaling and the function of cilia.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861735/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861735/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rink, Jochen C -- Gurley, Kyle A -- Elliott, Sarah A -- Sanchez Alvarado, Alejandro -- F32GM082016/GM/NIGMS NIH HHS/ -- R0-1 GM57260/GM/NIGMS NIH HHS/ -- R37 GM057260/GM/NIGMS NIH HHS/ -- R37 GM057260-11/GM/NIGMS NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2009 Dec 4;326(5958):1406-10. doi: 10.1126/science.1178712. Epub 2009 Oct 22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurobiology and Anatomy, Howard Hughes Medical Institute, University of Utah School of Medicine, 401 MREB, 20 North 1900 East, Salt Lake City, UT 84103, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19933103" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; Body Patterning ; Cilia/*physiology ; Genes, Helminth ; Hedgehog Proteins/genetics/*metabolism ; Helminth Proteins/genetics/metabolism ; Molecular Sequence Data ; Planarians/genetics/metabolism/*physiology ; RNA Interference ; *Regeneration ; *Signal Transduction ; Wnt Proteins/metabolism ; beta Catenin/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2009-05-23
    Description: Integrons are found in the genome of hundreds of environmental bacteria but are mainly known for their role in the capture and spread of antibiotic resistance determinants among Gram-negative pathogens. We report a direct link between this system and the ubiquitous SOS response. We found that LexA controlled expression of most integron integrases and consequently regulated cassette recombination. This regulatory coupling enhanced the potential for cassette swapping and capture in cells under stress, while minimizing cassette rearrangements or loss in constant environments. This finding exposes integrons as integrated adaptive systems and has implications for antibiotic treatment policies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Guerin, Emilie -- Cambray, Guillaume -- Sanchez-Alberola, Neus -- Campoy, Susana -- Erill, Ivan -- Da Re, Sandra -- Gonzalez-Zorn, Bruno -- Barbe, Jordi -- Ploy, Marie-Cecile -- Mazel, Didier -- New York, N.Y. -- Science. 2009 May 22;324(5930):1034. doi: 10.1126/science.1172914.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Universite de Limoges, Faculte de Medecine, EA3175, INSERM, Equipe Avenir, 87000 Limoges, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19460999" target="_blank"〉PubMed〈/a〉
    Keywords: Bacterial Proteins/metabolism ; Base Sequence ; Binding Sites ; Drug Resistance, Bacterial/genetics ; Escherichia coli/*genetics/metabolism ; Gene Expression Regulation, Bacterial ; Integrases/genetics ; Integrons/*genetics ; Molecular Sequence Data ; Promoter Regions, Genetic ; *Recombination, Genetic ; *SOS Response (Genetics) ; Serine Endopeptidases/metabolism ; Vibrio cholerae/*genetics/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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